2011
A Latent Variable Approach to Study Gene–Environment Interactions in the Presence of Multiple Correlated Exposures
Sánchez B, Kang S, Mukherjee B. A Latent Variable Approach to Study Gene–Environment Interactions in the Presence of Multiple Correlated Exposures. Biometrics 2011, 68: 466-476. PMID: 21955029, PMCID: PMC4405908, DOI: 10.1111/j.1541-0420.2011.01677.x.Peer-Reviewed Original ResearchMeSH KeywordsAnalysis of VarianceBiasBiometryBirth WeightCase-Control StudiesComputer SimulationEnvironmental ExposureEpidemiologic FactorsFemaleGene-Environment InteractionHumansInfant, NewbornIronLead PoisoningModels, StatisticalPregnancyPrenatal Exposure Delayed EffectsPrincipal Component AnalysisConceptsGene-environment interactionsGene-environmentEnvironmental epidemiologyCohort studyGene-environment dependenceBurden of multiple testingStudy gene-environment interactionsEnvironmental exposuresExposure dataEarly life exposuresLV frameworkG x E effectsHealth StudyCorrelated exposuresG x EDisease riskLife exposureMultiple testingFunction of environmental exposureE studyGenotype categoriesStudy of lead exposureBirth weightIron metabolism genesAdaptive trade-off
2008
Tests for gene‐environment interaction from case‐control data: a novel study of type I error, power and designs
Mukherjee B, Ahn J, Gruber S, Rennert G, Moreno V, Chatterjee N. Tests for gene‐environment interaction from case‐control data: a novel study of type I error, power and designs. Genetic Epidemiology 2008, 32: 615-626. PMID: 18473390, DOI: 10.1002/gepi.20337.Peer-Reviewed Original ResearchConceptsGene-environment independence assumptionCase-control studyGene-environment interactionsGene-environment associationsCase-onlyCase-control study of colorectal cancerDetection of gene-environment interactionsType I errorGene-environment dependenceStudy of colorectal cancerGene-environment independenceEffect of genetic susceptibilityCase-only methodCase-only estimatorCase-control estimatorsCase-control dataGene-environment effectsCase-control designCase-control methodCase-control analysisGlutathione S-transferase M1Empirical-BayesEpidemiological researchCase-controlColorectal cancer