2023
Associations Between Repeated Measures of Urinary Phthalate Metabolites With Hormones and Timing of Natural Menopause
Ding N, Zheutlin E, Harlow S, Randolph J, Mukherjee B, Park S. Associations Between Repeated Measures of Urinary Phthalate Metabolites With Hormones and Timing of Natural Menopause. Journal Of The Endocrine Society 2023, 7: bvad024. PMID: 36846211, PMCID: PMC9945847, DOI: 10.1210/jendso/bvad024.Peer-Reviewed Original ResearchSex hormone-binding globulinFollicle-stimulating hormoneAnti-Mullerian hormoneUrinary phthalate metabolitesTiming of natural menopausePhthalate metabolitesNatural menopauseExposure to phthalatesMeasures of urinary phthalate metabolitesAssociations of phthalate metabolitesHazard ratioAssociations of urinary phthalate metabolitesSerum concentrations of estradiolHormone-binding globulinCox proportional-hazards modelStudy of Women's HealthConcentrations of estradiolCalculate hazard ratiosProportional-hazards modelStatistically significant associationCirculating levels of testosteroneLevels of testosteroneHormone therapyOvarian reserveMidlife women
2022
Exposure to heavy metals and hormone levels in midlife women: The Study of Women's Health Across the Nation (SWAN)
Wang X, Ding N, Harlow S, Randolph J, Mukherjee B, Gold E, Park S. Exposure to heavy metals and hormone levels in midlife women: The Study of Women's Health Across the Nation (SWAN). Environmental Pollution 2022, 317: 120740. PMID: 36436662, PMCID: PMC9897061, DOI: 10.1016/j.envpol.2022.120740.Peer-Reviewed Original ResearchConceptsUrinary metal concentrationsExposure to heavy metalsHeavy metalsMetal concentrationsStudy of Women's HealthAssociation of heavy metalsEnvironmental heavy metal exposureHeavy metal exposureSex hormone-binding globulinFollicle-stimulating hormoneWomen's HealthBayesian kernel machine regressionAssociated with E<sub>2</sub>, TMidlife womenKernel machine regressionMetal exposureSerum hormone levelsMetal mixturesHealth-related factorsNation Multi-Pollutant StudyCalculate percent changesCadmiumHormone levelsProspective cohort studyLinear mixed effects modelsPerfluoroalkyl Substances and Incident Natural Menopause in Midlife Women: The Mediating Role of Sex Hormones
Ding N, Harlow S, Randolph J, Mukherjee B, Batterman S, Gold E, Park S. Perfluoroalkyl Substances and Incident Natural Menopause in Midlife Women: The Mediating Role of Sex Hormones. American Journal Of Epidemiology 2022, 191: 1212-1223. PMID: 35292812, PMCID: PMC9393069, DOI: 10.1093/aje/kwac052.Peer-Reviewed Original Research
2021
Per- and Polyfluoroalkyl Substances and Hormone Levels During the Menopausal Transition
Harlow S, Hood M, Ding N, Mukherjee B, Calafat A, Randolph J, Gold E, Park S. Per- and Polyfluoroalkyl Substances and Hormone Levels During the Menopausal Transition. The Journal Of Clinical Endocrinology & Metabolism 2021, 106: e4427-e4437. PMID: 34181018, PMCID: PMC8677593, DOI: 10.1210/clinem/dgab476.Peer-Reviewed Original ResearchConceptsMidlife womenSex hormone-binding globulinFollicle-stimulating hormoneInverse associationStudy of Women's HealthPositive associationMenopausal transitionBody mass indexReproductive ageWomen's HealthSignificant linear trendNo significant associationNulliparous womenLinear mixed modelsSmoking statusYears of ageMass indexHormone-binding globulinMenopausal statusLongitudinal serum concentrationsSignificant associationSerum PFAS concentrationsMidlifeWomenPolyfluoroalkyl substances
2020
The Mediating Role of Follicle-Stimulating Hormone in the Associations between Exposure to Perfluoroalkyl Substances and Incident Natural Menopause
Ding N, Harlow S, Randolph J, Mukherjee B, Batterman S, Gold E, Park S. The Mediating Role of Follicle-Stimulating Hormone in the Associations between Exposure to Perfluoroalkyl Substances and Incident Natural Menopause. ISEE Conference Abstracts 2020, 2020 DOI: 10.1289/isee.2020.virtual.p-0867.Peer-Reviewed Original ResearchFollicle-stimulating hormone