2025
Serum anti-mullerian hormone levels and age among Samoan women
O’Brien G, Lambert-Messerlian G, Hawley N, Fidow U, Naseri T, Reupena M, Kershaw E, Azar M, Pangburn M, McGarvey S. Serum anti-mullerian hormone levels and age among Samoan women. Reproductive Biology And Endocrinology 2025, 23: 45. PMID: 40108611, PMCID: PMC11921511, DOI: 10.1186/s12958-025-01379-y.Peer-Reviewed Original ResearchConceptsPCOS prevalencePolycystic ovary syndromeSerum anti-Mullerian hormoneAnti-Mullerian hormoneAnti-Mullerian hormone levelsSamoan womenAssociation of anti-Mullerian hormoneContraceptive useBody mass indexSerum anti-mullerian hormone levelsEthnic minority populationsHormonal contraceptive useAMH levelsAssociated with ageFree androgen indexMinority populationsSex hormone binding globulinReproductive healthAssociated with body mass indexSerum total testosteroneAndrogen indexPrevalence of obesityRelated declineTobacco useAdult womenBehavioral and sociodemographic correlates of sleep duration among children in Samoa
von Ash T, Choy C, Dunsiger S, Soti-Ulberg C, Wang D, Reupena M, Duckham R, Naseri T, Hawley N. Behavioral and sociodemographic correlates of sleep duration among children in Samoa. Sleep Health 2025, 11: 57-64. PMID: 39753399, PMCID: PMC11805616, DOI: 10.1016/j.sleh.2024.10.009.Peer-Reviewed Original ResearchConceptsSchool-aged childrenSociodemographic correlatesPrimary caregiversSleep durationSleep recommendationsAssociated with longer sleepCorrelates of sleepCorrelates of sleep durationLongitudinal cohort studyShort sleepDietary pattern adherenceAged 2Total carbohydrate intakeData collection wavesNighttime sleepSamoan childrenChildren aged 2Physical activityChild healthSociodemographic characteristicsAdequate sleepCarbohydrate intakeCollection wavesInsufficient sleepRisk factors
2024
Prediction of neonatal survival among Pacific Islander preterm births in the US
Wu B, Taylor S, Shabanova V, Hawley N. Prediction of neonatal survival among Pacific Islander preterm births in the US. PLOS ONE 2024, 19: e0316048. PMID: 39739767, PMCID: PMC11687717, DOI: 10.1371/journal.pone.0316048.Peer-Reviewed Original ResearchConceptsGestational ageNeonatal sexBirth weightNeonatal mortalityNeonatal survivalPreterm birthBorn large-for-gestational ageLarge-for-gestational ageObesity-related risk factorsPrediction of neonatal survivalPre-pregnancy obesityGroup of neonatesMortality rateNeonatal mortality rateUnited States National Center for Health StatisticsDeath data filesPacific Islander mothersPredicted survival ratesGestational weeksPre-pregnancyNeonatal deathCongenital anomaliesGestationSurvival rateRisk factorsA group prenatal care intervention reduces gestational weight gain and gestational diabetes in American Samoan women
Hawley N, Faasalele‐Savusa K, Faiai M, Suiaunoa‐Scanlan L, Loia M, Ickovics J, Kocher E, Piel C, Mahoney M, Suss R, Trocha M, Rosen R, Muasau‐Howard B. A group prenatal care intervention reduces gestational weight gain and gestational diabetes in American Samoan women. Obesity 2024, 32: 1833-1843. PMID: 39256170, PMCID: PMC11755376, DOI: 10.1002/oby.24102.Peer-Reviewed Original ResearchConceptsGestational weight gainPostpartum weight changeGestational diabetes screeningClinically important between-group differenceDiabetes screeningGestational diabetesUsual care participantsPrenatal care interventionsMode of birthLow-risk pregnant womenPre-pregnancy obesityAmerican Samoan womenIncidence of gestational diabetesProportion of womenGestational diabetes incidenceInfant birth weightWeight gainBetween-group differencesCare interventionsCare participantsPreliminary effectivenessWeight changeRandom group assignmentDiabetes incidenceHigh-risk settingsAssociations between fasting glucose rate-of-change and the missense variant, rs373863828, in an adult Samoan cohort
Rivara A, Russell E, Carlson J, Pomer A, Naseri T, Reupena M, Manna S, Viali S, Minster R, Weeks D, DeLany J, Kershaw E, McGarvey S, Hawley N. Associations between fasting glucose rate-of-change and the missense variant, rs373863828, in an adult Samoan cohort. PLOS ONE 2024, 19: e0302643. PMID: 38829901, PMCID: PMC11146712, DOI: 10.1371/journal.pone.0302643.Peer-Reviewed Original ResearchConceptsType 2 diabetesAllele of rs373863828Body mass indexFasting glucoseAdult SamoansDevelopment of type 2 diabetesOdds of type 2 diabetesReduction of modifiable risk factorsRs373863828 genotypeAssociated with higher body mass indexType 2 diabetes developmentGlucose rate of changeMass indexHousehold asset scoreUrbanization of residenceHigher body mass indexRisk factorsModifiable risk factorsRate of changeBaseline variablesMultivariate linear regressionPhysical activityDiabetes preventionType 2 diabetes mellitusSmoking statusThe milk study protocol: A longitudinal, prospective cohort study of the relationship between human milk metabolic hormone concentration, maternal body composition, and early growth and satiety development in Samoan infants aged 1–4 months
Harries V, Abraham J, Vesi L, Reupena A, Faaselele-Savusa K, Duckham R, Bribiescas R, Hawley N. The milk study protocol: A longitudinal, prospective cohort study of the relationship between human milk metabolic hormone concentration, maternal body composition, and early growth and satiety development in Samoan infants aged 1–4 months. PLOS ONE 2024, 19: e0292997. PMID: 38728264, PMCID: PMC11086876, DOI: 10.1371/journal.pone.0292997.Peer-Reviewed Original ResearchConceptsMaternal body compositionEarly infant growthBody compositionInfant growthProspective longitudinal cohortMother-infant dyadsBreastfeeding mother-infant dyadsHuman milkFingerpick blood sampleInfants aged 1Longitudinal cohortBody composition measurementsProspective cohort studyInfant feeding patternsSatiety developmentUndernourished womenSatiety responsivenessInfant satietyInfant hungerHormone leptinCohort studyHigh-income settingsMultivariate analysisEating patternsHormone transferScreening for Hypertension in adolescents living with HIV: Protocol for a cluster randomized trial to improve guideline adherence
Adu-Gyamfi R, Enos J, Yeboah K, Shabanova V, Hawley N, Ogum D, Nkansah A, Paintsil E, Torpey K. Screening for Hypertension in adolescents living with HIV: Protocol for a cluster randomized trial to improve guideline adherence. PLOS ONE 2024, 19: e0302016. PMID: 38701070, PMCID: PMC11068165, DOI: 10.1371/journal.pone.0302016.Peer-Reviewed Original ResearchConceptsTheory-based interventionsImplementation of clinical practice guidelinesClinic visitsProvision of job aidsHealthcare workers' adherenceCluster randomized trialAvailability of guidelinesClinical practice guidelinesBehavior-based interventionsCluster-randomized studyAntiretroviral therapy sitesCardiovascular disease-related morbidityBlood pressureAIDS-related deathsIntervention facilitiesGreater Accra Region of GhanaAccra Region of GhanaGuideline adherenceHypertension screeningAntiretroviral careWorker adherenceIncidence of hypertensionHypertension riskGreater Accra RegionJob aidsChild routines moderate a brief behavioral intervention to enhance sleep in school-aged children
Gebre A, Hawley N, Carskadon M, Raynor H, Jelalian E, Owens J, Wing R, Hart C. Child routines moderate a brief behavioral intervention to enhance sleep in school-aged children. Journal Of Pediatric Psychology 2024, 49: 365-371. PMID: 38553029, PMCID: PMC11098045, DOI: 10.1093/jpepsy/jsae015.Peer-Reviewed Original ResearchConceptsMonths post-randomizationSchool-aged childrenBehavioral sleep interventionsPost-randomizationBehavioral interventionsSleep interventionsChild routinesChild Routines InventoryEnhance sleepIntervention groupRoutine behaviorSecondary analysisSleep periodIntervention responseInterventionShort sleepWrist actigraphyModeration analysisRoutines InventoryPROCESS macroBehavior modificationChildrenBaselineTreatment conditionsSleep
2023
Identifying patient preferences for diabetes care: A protocol for implementing a discrete choice experiment in Samoa
Rivara A, Galárraga O, Selu M, Arorae M, Wang R, Faasalele-Savusa K, Rosen R, Hawley N, Viali S. Identifying patient preferences for diabetes care: A protocol for implementing a discrete choice experiment in Samoa. PLOS ONE 2023, 18: e0295845. PMID: 38134044, PMCID: PMC10745180, DOI: 10.1371/journal.pone.0295845.Peer-Reviewed Original Research“There are still broken or fragmented systems”: Qualitative assessment of needs to strengthen adolescent mental health services in American Samoa
Mew E, Blas V, Winschel J, Hunt L, Soliai‐Lemusu S, Johansson A, Lowe S, Faiai M, Naseri J, Toelupe R, Ipou F, Seui M, Ledoux‐Sunia T, Sunia F, Galea’i A, Poulin R, Hawley N, McCutchan‐Tofaeono J. “There are still broken or fragmented systems”: Qualitative assessment of needs to strengthen adolescent mental health services in American Samoa. International Journal Of Mental Health Nursing 2023, 33: 85-92. PMID: 37691318, PMCID: PMC10872981, DOI: 10.1111/inm.13223.Peer-Reviewed Original ResearchConceptsHealth needsAdolescent mental healthMental healthAdolescent mental health servicesCommon mental health problemsMental health servicesAdolescent health needsPost-traumatic stress disorderMental health needsMental health systemMental health problemsAdolescent mental health needsRegion of residenceHealth burdenHigh burdenMental health challengesTreatment accessHealth problemsHealth servicesHealth challengesHealth systemStress disorderAssociation between age at menarche and cardiometabolic risk among Samoan adults
Oyama S, Duckham R, Pomer A, Rivara A, Kershaw E, Wood A, Fidow U, Naseri T, Reupena M, Viali S, McGarvey S, Hawley N. Association between age at menarche and cardiometabolic risk among Samoan adults. American Journal Of Human Biology 2023, 36: e23982. PMID: 37668413, PMCID: PMC10845161, DOI: 10.1002/ajhb.23982.Peer-Reviewed Original ResearchConceptsCardiometabolic riskOne-year increaseSubsequent cardiometabolic riskOdds of hypertensionHigher total cholesterolOdds of diabetesOdds of obesityEarly life exposureFat-free massCardiometabolic morbiditySerum lipidsBlood pressureMedian ageMetabolic syndromeTotal cholesterolProspective studyChildhood adiposityInsulin resistanceObesity prevalenceLife exposureSamoan adultsLean massEarly menarcheLogistic regressionMenarcheEpigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma
Recto K, Kachroo P, Huan T, Van Den Berg D, Lee G, Bui H, Lee D, Gereige J, Yao C, Hwang S, Joehanes R, Weiss S, Consortium N, Abe N, Abecasis G, Aguet F, Albert C, Almasy L, Alonso A, Ament S, Anderson P, Anugu P, Applebaum-Bowden D, Ardlie K, Arking D, Arnett D, Ashley-Koch A, Aslibekyan S, Assimes T, Auer P, Avramopoulos D, Ayas N, Balasubramanian A, Barnard J, Barnes K, Barr R, Barron-Casella E, Barwick L, Beaty T, Beck G, Becker D, Becker L, Beer R, Beitelshees A, Benjamin E, Benos T, Bezerra M, Bielak L, Bis J, Blackwell T, Blangero J, Blue N, Boerwinkle E, Bowden D, Bowler R, Brody J, Broeckel U, Broome J, Brown D, Bunting K, Burchard E, Bustamante C, Buth E, Cade B, Cardwell J, Carey V, Carrier J, Carson A, Carty C, Casaburi R, Romero J, Casella J, Castaldi P, Chaffin M, Chang C, Chang Y, Chasman D, Chavan S, Chen B, Chen W, Chen Y, Cho M, Choi S, Chuang L, Chung M, Chung R, Clish C, Comhair S, Conomos M, Cornell E, Correa A, Crandall C, Crapo J, Cupples L, Curran J, Curtis J, Custer B, Damcott C, Darbar D, David S, Davis C, Daya M, de Andrade M, de las Fuentes L, de Vries P, DeBaun M, Deka R, DeMeo D, Devine S, Dinh H, Doddapaneni H, Duan Q, Dugan-Perez S, Duggirala R, Durda J, Dutcher S, Eaton C, Ekunwe L, Boueiz A, Ellinor P, Emery L, Erzurum S, Farber C, Farek J, Fingerlin T, Flickinger M, Fornage M, Franceschini N, Frazar C, Fu M, Fullerton S, Fulton L, Gabriel S, Gan W, Gao S, Gao Y, Gass M, Geiger H, Gelb B, Geraci M, Germer S, Gerszten R, Ghosh A, Gibbs R, Gignoux C, Gladwin M, Glahn D, Gogarten S, Gong D, Goring H, Graw S, Gray K, Grine D, Gross C, Gu C, Guan Y, Guo X, Gupta N, Haessler J, Hall M, Han Y, Hanly P, Harris D, Hawley N, He J, Heavner B, Heckbert S, Hernandez R, Herrington D, Hersh C, Hidalgo B, Hixson J, Hobbs B, Hokanson J, Hong E, Hoth K, Hsiung C, Hu J, Hung Y, Huston H, Hwu C, Irvin M, Jackson R, Jain D, Jaquish C, Johnsen J, Johnson A, Johnson C, Johnston R, Jones K, Kang H, Kaplan R, Kardia S, Kelly S, Kenny E, Kessler M, Khan A, Khan Z, Kim W, Kimoff J, Kinney G, Konkle B, Kooperberg C, Kramer H, Lange C, Lange E, Lange L, Laurie C, Laurie C, LeBoff M, Lee J, Lee S, Lee W, LeFaive J, Levine D, Levy D, Lewis J, Li X, Li Y, Lin H, Lin H, Lin X, Liu S, Liu Y, Liu Y, Loos R, Lubitz S, Lunetta K, Luo J, Magalang U, Mahaney M, Make B, Manichaikul A, Manning A, Manson J, Martin L, Marton M, Mathai S, Mathias R, May S, McArdle P, McDonald M, McFarland S, McGarvey S, McGoldrick D, McHugh C, McNeil B, Mei H, Meigs J, Menon V, Mestroni L, Metcalf G, Meyers D, Mignot E, Mikulla J, Min N, Minear M, Minster R, Mitchell B, Moll M, Momin Z, Montasser M, Montgomery C, Muzny D, Mychaleckyj J, Nadkarni G, Naik R, Naseri T, Natarajan P, Nekhai S, Nelson S, Neltner B, Nessner C, Nickerson D, Nkechinyere O, North K, O'Connell J, O'Connor T, Ochs-Balcom H, Okwuonu G, Pack A, Paik D, Palmer N, Pankow J, Papanicolaou G, Parker C, Peloso G, Peralta J, Perez M, Perry J, Peters U, Peyser P, Phillips L, Pleiness J, Pollin T, Post W, Becker J, Boorgula M, Preuss M, Psaty B, Qasba P, Qiao D, Qin Z, Rafaels N, Raffield L, Rajendran M, Ramachandran V, Rao D, Rasmussen-Torvik L, Ratan A, Redline S, Reed R, Reeves C, Regan E, Reiner A, Reupena M, Rice K, Rich S, Robillard R, Robine N, Roden D, Roselli C, Rotter J, Ruczinski I, Runnels A, Russell P, Ruuska S, Ryan K, Sabino E, Saleheen D, Salimi S, Salvi S, Salzberg S, Sandow K, Sankaran V, Santibanez J, Schwander K, Schwartz D, Sciurba F, Seidman C, Seidman J, Sériès F, Sheehan V, Sherman S, Shetty A, Shetty A, Sheu W, Shoemaker M, Silver B, Silverman E, Skomro R, Smith A, Smith J, Smith J, Smith N, Smith T, Smoller S, Snively B, Snyder M, Sofer T, Sotoodehnia N, Stilp A, Storm G, Streeten E, Su J, Sung Y, Sylvia J, Szpiro A, Taliun D, Tang H, Taub M, Taylor K, Taylor M, Taylor S, Telen M, Thornton T, Threlkeld M, Tinker L, Tirschwell D, Tishkoff S, Tiwari H, Tong C, Tracy R, Tsai M, Vaidya D, Van Den Berg D, VandeHaar P, Vrieze S, Walker T, Wallace R, Walts A, Wang F, Wang H, Wang J, Watson K, Watt J, Weeks D, Weinstock J, Weir B, Weiss S, Weng L, Wessel J, Willer C, Williams K, Williams L, Williams S, Wilson C, Wilson J, Winterkorn L, Wong Q, Wu B, Wu J, Xu H, Yanek L, Yang I, Yu K, Zekavat S, Zhang Y, Zhao S, Zhao W, Zhu X, Ziv E, Zody M, Zoellner S, O’Connor G, Levy D, DeMeo D. Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma. EBioMedicine 2023, 95: 104758. PMID: 37598461, PMCID: PMC10462855, DOI: 10.1016/j.ebiom.2023.104758.Peer-Reviewed Original ResearchConceptsMethylation quantitative trait lociAssociation studiesNovel epigenetic signatureIdentifies novel targetsQuantitative trait lociTranscription factor bindingEpigenome-wide association studiesGene ontology analysisWide association studyClosest genesTrait lociCausal regulatorsDrug target analysisTranscription patternsOntology analysisDNA methylationEpigenetic signaturesFactor bindingGene expressionMolecular mechanismsMendelian randomizationCosta Rica StudyPotential therapeutic targetNovel targetGenetic epidemiologyBirth-Based vs Fetuses-at-Risk Approaches for Assessing Neonatal Mortality Rate by Race
Wu B, Taylor S, Shabanova V, Hawley N. Birth-Based vs Fetuses-at-Risk Approaches for Assessing Neonatal Mortality Rate by Race. JAMA Pediatrics 2023, 177: 633-635. PMID: 37093613, PMCID: PMC10126942, DOI: 10.1001/jamapediatrics.2023.0333.Commentaries, Editorials and LettersA Polynesian-specific missense CETP variant alters the lipid profile
Moors J, Krishnan M, Sumpter N, Takei R, Bixley M, Cadzow M, Major T, Phipps-Green A, Topless R, Merriman M, Rutledge M, Morgan B, Carlson J, Zhang J, Russell E, Sun G, Cheng H, Weeks D, Naseri T, Reupena M, Viali S, Tuitele J, Hawley N, Deka R, McGarvey S, de Zoysa J, Murphy R, Dalbeth N, Stamp L, Taumoepeau M, King F, Wilcox P, Rapana N, McCormick S, Minster R, Merriman T, Leask M. A Polynesian-specific missense CETP variant alters the lipid profile. Human Genetics And Genomics Advances 2023, 4: 100204. PMID: 37250494, PMCID: PMC10209881, DOI: 10.1016/j.xhgg.2023.100204.Peer-Reviewed Original ResearchConceptsPopulation-specific genetic variantsGenomic studiesGenetic analysisFunction mutationsVariant altersGenetic determinantsGenetic variantsMinor alleleCETP deficiencyGenomicsHigher HDLLipid profileTraitsSequencingLow LDL-C levelsMutationsAllelesLDL-C levelsSerum lipid profileCopiesPolymorphismAssociatesLower LDLCardiovascular diseaseVariantsPreterm birth among Pacific Islanders in the United States and the US‐affiliated Pacific Islands: A systematic review and meta‐analysis
Wu B, Arslanian K, Nyhan K, Suss R, Mahoney M, McElfish P, Muasau‐Howard B, Ekeroma A, Hawley N. Preterm birth among Pacific Islanders in the United States and the US‐affiliated Pacific Islands: A systematic review and meta‐analysis. Birth 2023, 50: 287-299. PMID: 37060205, PMCID: PMC10577805, DOI: 10.1111/birt.12713.Peer-Reviewed Original ResearchConceptsPreterm birthPooled prevalencePacific Islander subgroupsWhite womenRisk factorsPacific IslandersPre-pregnancy body mass indexUS-Affiliated Pacific IslandsBody mass indexHighest pooled prevalencePerinatal health disparitiesPreterm birth prevalencePreterm birth outcomesOutcomes of interestRandom-effects modelPacific Islander womenBirth outcomesMass indexObservational studyPooled estimatesBirth prevalenceHigher oddsSystematic reviewMarshallese womenHealth disparitiesCross-sectional and prospective associations between household socioeconomic resources, appetite traits, and body size among Samoan infants
Oyama S, Arslanian K, Fidow U, Naseri T, Soti-Ulberg C, Hawley N. Cross-sectional and prospective associations between household socioeconomic resources, appetite traits, and body size among Samoan infants. Appetite 2023, 185: 106519. PMID: 36870391, DOI: 10.1016/j.appet.2023.106519.Peer-Reviewed Original ResearchAssociation of rs9939609 in FTO with BMI among Polynesian peoples living in Aotearoa New Zealand and other Pacific nations
Krishnan M, Phipps-Green A, Russell E, Major T, Cadzow M, Stamp L, Dalbeth N, Hindmarsh J, Qasim M, Watson H, Liu S, Carlson J, Minster R, Hawley N, Naseri T, Reupena M, Deka R, McGarvey S, Merriman T, Murphy R, Weeks D. Association of rs9939609 in FTO with BMI among Polynesian peoples living in Aotearoa New Zealand and other Pacific nations. Journal Of Human Genetics 2023, 68: 463-468. PMID: 36864286, PMCID: PMC10313811, DOI: 10.1038/s10038-023-01141-5.Peer-Reviewed Original ResearchConceptsBody mass indexMean body mass indexHigher body mass indexPrevious smaller studiesAssociation of rs9939609New Zealand PolynesiansMass indexFat massSmall studySignificant associationPolynesian ancestryFTO variantsRs9939609Effect size estimatesAssociationSimilar effectsMean effect size estimateProtocol: Implementation and evaluation of an adolescent-mediated intervention to improve glycemic control and diabetes self-management among Samoan adults
Hawley N, Rivara A, Naseri J, Faumuina K, Potoa’e-Solaita N, Iopu F, Faiai M, Naveno E, Tasele S, Lefale T, Lantini R, Carlson J, Rabin T, Semaia P, Mugadza P, Rosen R. Protocol: Implementation and evaluation of an adolescent-mediated intervention to improve glycemic control and diabetes self-management among Samoan adults. PLOS ONE 2023, 18: e0279084. PMID: 36795707, PMCID: PMC9934313, DOI: 10.1371/journal.pone.0279084.Peer-Reviewed Original ResearchConceptsGlycemic controlPrimary efficacy outcomeCardiovascular risk factorsChronic disease riskType 2 diabetesSelf-care strategiesSelf-care practicesHealth behavior changeBehavior changeEfficacy outcomesUsual careDiabetes InterventionsAdult family membersRisk factorsDiabetes knowledgeSamoan adultsIntervention acceptabilityFamily-centered culturePositive behavior changeDisease riskHealth disparitiesActive interventionDisproportionate riskInterventionEthnic minority groupsMulti-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing
Chen F, Wang X, Jang S, Quach B, Weissenkampen J, Khunsriraksakul C, Yang L, Sauteraud R, Albert C, Allred N, Arnett D, Ashley-Koch A, Barnes K, Barr R, Becker D, Bielak L, Bis J, Blangero J, Boorgula M, Chasman D, Chavan S, Chen Y, Chuang L, Correa A, Curran J, David S, Fuentes L, Deka R, Duggirala R, Faul J, Garrett M, Gharib S, Guo X, Hall M, Hawley N, He J, Hobbs B, Hokanson J, Hsiung C, Hwang S, Hyde T, Irvin M, Jaffe A, Johnson E, Kaplan R, Kardia S, Kaufman J, Kelly T, Kleinman J, Kooperberg C, Lee I, Levy D, Lutz S, Manichaikul A, Martin L, Marx O, McGarvey S, Minster R, Moll M, Moussa K, Naseri T, North K, Oelsner E, Peralta J, Peyser P, Psaty B, Rafaels N, Raffield L, Reupena M, Rich S, Rotter J, Schwartz D, Shadyab A, Sheu W, Sims M, Smith J, Sun X, Taylor K, Telen M, Watson H, Weeks D, Weir D, Yanek L, Young K, Young K, Zhao W, Hancock D, Jiang B, Vrieze S, Liu D. Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing. Nature Genetics 2023, 55: 291-300. PMID: 36702996, PMCID: PMC9925385, DOI: 10.1038/s41588-022-01282-x.Peer-Reviewed Original ResearchConceptsTWAS methodsExpression quantitative trait loci (eQTL) dataQuantitative trait loci dataTranscriptome-wide associationWide association studyGenome-wide association study summary statisticsWhole genome sequencesSubsequent fine mappingEQTL datasetNew genesLoci dataFine mappingPhenotypic effectsTobacco use phenotypesDiverse ancestryAssociation studiesBiological relevanceEuropean ancestryGenesAncestryGWASSummary statisticsBiologyDrug repurposingDiversityScoping review protocol of multicomponent interventions to address cardiometabolic disease risk among Pacific Islander children
Choy C, Nyhan K, Savusa K, Soti-Ulberg C, Rosen R, Naseri T, Hawley N, Sharifi M. Scoping review protocol of multicomponent interventions to address cardiometabolic disease risk among Pacific Islander children. PLOS ONE 2023, 18: e0280888. PMID: 36689458, PMCID: PMC9870166, DOI: 10.1371/journal.pone.0280888.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPacific Islander childrenCMD risk factorsMulticomponent interventionRisk factorsCardiometabolic disease risk factorsDisease risk factorsCardiometabolic disease riskClinical trial registrationPreferred Reporting ItemsJoanna Briggs Institute ManualFormal ethical approvalTRIAL REGISTRATIONCochrane LibraryHigh prevalenceEligible interventionsStudy populationEthical approvalReporting ItemsCMD riskDisease riskIntervention componentsProQuest DissertationsReview protocolEvidence mappingEvidence synthesis
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