2025
Retention and dropout from sublingual and extended-release buprenorphine treatment: A comparative analysis of data from a nationally representative sample of commercially-insured people with opiod use disorder in the United States
Ivasiy R, Madden L, Johnson K, Machavariani E, Ahmad B, Oliveros D, Tan J, Kil N, Altice F. Retention and dropout from sublingual and extended-release buprenorphine treatment: A comparative analysis of data from a nationally representative sample of commercially-insured people with opiod use disorder in the United States. International Journal Of Drug Policy 2025, 138: 104748. PMID: 40020306, DOI: 10.1016/j.drugpo.2025.104748.Peer-Reviewed Original ResearchConceptsOpioid use disorderSL-BUPXR-BUPUse disorderRetrospective cohort studyExtended-release buprenorphineReduce treatment discontinuationDays of supplyTreatment discontinuationSublingual buprenorphineReduce overdose riskBuprenorphine treatmentCohort studyHigh dosesPrimary outcomeImpact of dosagePatientsBuprenorphineMonthsMg/dayCommercially-insured individualsProportion of individualsOpioidOverdose riskImprove health outcomesPrescribing methadone in prison predicts linkage to HIV care after release from prison: A randomized and patient preference trial
Mobley A, Wegman M, Bazazi A, Shenoi S, Bromberg D, Ahmad A, Kamarulzaman A, Altice F. Prescribing methadone in prison predicts linkage to HIV care after release from prison: A randomized and patient preference trial. International Journal Of Drug Policy 2025, 137: 104733. PMID: 39923270, PMCID: PMC11875876, DOI: 10.1016/j.drugpo.2025.104733.Peer-Reviewed Original ResearchConceptsLinkage to HIV careHIV careIncrease linkage to HIV careTreatment-as-prevention strategiesHIV treatment cascadeHIV treatment outcomesOpen-label trialCox proportional hazards modelsPatient preference trialOpioid use disorderMalaysia’s largest prison.Impact of methadoneProportional hazards modelTreatment cascadeInverse probability weighted Cox proportional hazards modelAnalytic sampleStudy participantsCareTreatment outcomesPrescribed methadoneOpioidConfounding variablesHIVUse disorderHazards modelRationale and design of a randomized clinical trial of integrated eHealth for PrEP and medications for opioid use disorders for women in the criminal legal system. The Athena study
Meyer J, Brunson S, Price C, Mulrain M, Nguyen J, Altice F, Kyriakides T, Cropsey K, Eaton E. Rationale and design of a randomized clinical trial of integrated eHealth for PrEP and medications for opioid use disorders for women in the criminal legal system. The Athena study. Addiction Science & Clinical Practice 2025, 20: 4. PMID: 39825419, PMCID: PMC11742507, DOI: 10.1186/s13722-024-00534-x.Peer-Reviewed Original ResearchConceptsCriminal legal systemOpioid use disorderLegal systemStandard of careStructural barriersUse disorderEnhanced standard of careRates of opioid use disorderDelivery of PrEPPre-exposure prophylaxisWomen's abilityRandomized clinical trialsLife-saving interventionsRandomized controlled trialsHealth disparitiesImplementation outcomesPrEP initiationPreventive servicesClinical outcomesIntegrated deliveryFollow-upDelivery modelsClinical trialsDecision aidPrEP
2024
Decrease in provider stigma is associated with improved quality health indicators among individuals receiving methadone in primary care centers in Ukraine
Machavariani E, Bromberg D, Dumchev K, Esserman D, Earnshaw V, Pykalo I, Filippovich M, Ivasiy R, Ahmad B, Long J, Haddad M, Madden L, Oliveros D, Dvoriak S, Altice F. Decrease in provider stigma is associated with improved quality health indicators among individuals receiving methadone in primary care centers in Ukraine. International Journal Of Drug Policy 2024, 136: 104682. PMID: 39705875, PMCID: PMC11821433, DOI: 10.1016/j.drugpo.2024.104682.Peer-Reviewed Original ResearchConceptsPrimary care centersQuality health indicatorsProvider stigmaEvidence-based practiceGuideline-concordantPatient outcomesHealth indicatorsReduce provider stigmaCare centerInfluence healthcare utilizationSpecialty health servicesPatient-level outcomesTele-educationImprove patient outcomesProvider fearsImplementation trialHealthcare utilizationPreventive careHealth servicesPoor healthLinear mixed-effects modelsImprove attitudesStigmaIncrease accessMixed-effects modelsComparing the brief Holistic Health for HIV (3H+) to the Holistic Health Recovery Program (HHRP+) among people with HIV and opioid use disorder: Results from a randomized, controlled non-inferiority trial
Zelenev A, Huedo-Medina T, Shrestha R, Mistler C, Altice F, Sibilio B, Copenhaver M. Comparing the brief Holistic Health for HIV (3H+) to the Holistic Health Recovery Program (HHRP+) among people with HIV and opioid use disorder: Results from a randomized, controlled non-inferiority trial. PLOS ONE 2024, 19: e0312165. PMID: 39509356, PMCID: PMC11542883, DOI: 10.1371/journal.pone.0312165.Peer-Reviewed Original ResearchConceptsHolistic Health Recovery ProgramEvidence-based interventionsHolistic healthHIV treatmentRisk behaviorsReduce HIV risk behaviorsDifference-in-differencesEnd-of-interventionControlled non-inferiority trialHIV Epidemic goalsDrug treatment settingsAttainment of viral suppressionNon-inferiority trialRecovery programViral suppressionHigh ART adherenceHIV risk behaviorsNon-inferiorityHHRP+ART adherenceBehavioral interventionsReal-world settingsNon-parametric bootstrappingCondom useOpioid-dependent peopleUsing nominal group technique with people who are incarcerated in Canadian federal prisons to identify barriers and solutions to improving Prison Needle Exchange Program uptake
Lafferty L, Altice F, Leone F, Stoové M, Lloyd A, Hajarizadeh B, Kronfli N. Using nominal group technique with people who are incarcerated in Canadian federal prisons to identify barriers and solutions to improving Prison Needle Exchange Program uptake. International Journal Of Drug Policy 2024, 131: 104549. PMID: 39141957, DOI: 10.1016/j.drugpo.2024.104549.Peer-Reviewed Original ResearchConceptsCanadian federal prisonsFederal prisonsPeer advocatesProgram participantsWrap-around servicesCorrectional authoritiesPrisonParticipant confidentialityFear of repercussionsHarm reductionLack of confidentialityPerceived repercussionsPriority barriersNeedle exchange programsParticipants' narrativesDrug useAdvocatesVotingAccess barriersIdentity processesImprove accessFocus groupsNominal group techniqueConfidentialityInterview transcriptsHigh rates of deferring antiretroviral treatment for patients with HIV and substance use disorders: Results from a national sample of HIV physicians in Ukraine
Ottesen T, Wickersham J, Lawrence J, Antoniak S, Zezuilin O, Polonsky M, Antonyak S, Rozanova J, Dvoriak S, Pykalo I, Filippovych M, Altice F. High rates of deferring antiretroviral treatment for patients with HIV and substance use disorders: Results from a national sample of HIV physicians in Ukraine. PLOS ONE 2024, 19: e0305086. PMID: 39028735, PMCID: PMC11259278, DOI: 10.1371/journal.pone.0305086.Peer-Reviewed Original ResearchConceptsAntiretroviral therapy prescriptionAntiretroviral therapyCD4 countSubstance use disordersIncreased levels of stigmaNational sampleLevel of stigmaIndependent of risk groupSuboptimal antiretroviral therapyInitiate antiretroviral therapyPopulation of peopleHIV expertsHIV incidenceHIV physiciansHIV treatmentKey populationsTransgender womenAntiretroviral treatmentFeeling thermometerDrinking alcoholSex workersPhysiciansSex partnersPWHRisk groupsInfluence of Stigma on Engagement in HIV Care and Adherence to Antiretroviral Therapy in Specialized HIV Clinics Targeting Men Who Have Sex with Men and Transgender Women in Lima, Peru
Oliveros Gómez D, Machavariani E, Altice F, Gálvez de León S, Earnshaw V, Montenegro-Idrogo J, Sánchez J, Seminario A. Influence of Stigma on Engagement in HIV Care and Adherence to Antiretroviral Therapy in Specialized HIV Clinics Targeting Men Who Have Sex with Men and Transgender Women in Lima, Peru. AIDS And Behavior 2024, 28: 2755-2768. PMID: 38878137, DOI: 10.1007/s10461-024-04401-3.Peer-Reviewed Original ResearchConceptsAdherence to antiretroviral therapyART adherenceTransgender womenHIV careSocial determinants of healthDeterminants of healthMultiple health outcomesInfluence of stigmaHIV-related outcomesViral suppression levelsGender minoritiesStigma subscaleAntiretroviral therapyHIV stigmaHealthcare engagementSocial determinantsHealth outcomesHIV clinicHIV epidemicStigmaVulnerable populationsCareOutcome variablesAssess factorsAdherenceHIV Activist Identity, Commitment, and Orientation Scale (HAICOS): Psychometric Evaluation to Assess Clinician’s Propensity Towards HIV Activism in Malaysia
Chong N, Azwa I, Hassan A, Mousavi M, Wong P, Ng R, Saifi R, Basri S, Omar S, Walters S, Collier Z, Haddad M, Altice F, Kamarulzaman A, Earnshaw V. HIV Activist Identity, Commitment, and Orientation Scale (HAICOS): Psychometric Evaluation to Assess Clinician’s Propensity Towards HIV Activism in Malaysia. AIDS And Behavior 2024, 28: 2780-2792. PMID: 38806844, PMCID: PMC11827331, DOI: 10.1007/s10461-024-04381-4.Peer-Reviewed Original ResearchConceptsExploratory factor analysisHIV-related stigmaIntra-class correlation coefficientPrimary care physiciansTest-retest reliabilityCronbach's alpha valuesOrientation ScaleCare physiciansStigma-relatedPsychometric evaluationHIV treatmentHIV activityAlpha valuesPsychometric qualitiesActivist identitiesHIVClinical practiceFactor analysisCliniciansCorrelation coefficientDay-to-dayStructured activitiesCronbachStigmaPhysiciansImplementation of REDCap mobile app in an oral HIV clinical study
Seminario A, Karczewski A, Stanley S, Huamani J, Montenegro J, Tafur K, Julca A, Altice F. Implementation of REDCap mobile app in an oral HIV clinical study. BMC Public Health 2024, 24: 629. PMID: 38413910, PMCID: PMC10900554, DOI: 10.1186/s12889-024-17837-y.Peer-Reviewed Original ResearchConceptsAlcohol use disorderLow-middle income countriesOral healthAssociation of alcohol use disordersPerceived oral health statusAvailability of anti-retroviral therapyLevels of oral diseaseOral health statusAnti-retroviral therapyMobile appsElectronic data collection systemResultsThe mean ageHIV clinical studiesDietary supplement useClinical research staffHIV stigmaOral diseasesHIV clinicHIV casesHealth statusHIV statusMean ageClinical studiesParticipants' experiencesMedical history
2023
The Cooperative Re-Engagement Controlled Trial (CoRECT): Durable Viral Suppression Assessment
O'Shea J, Fanfair R, Williams T, Khalil G, Brady K, DeMaria A, Villanueva M, Randall L, Jenkins H, Altice F, Camp N, Lucas C, Buchelli M, Samandari T, Weidle P. The Cooperative Re-Engagement Controlled Trial (CoRECT): Durable Viral Suppression Assessment. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2023, 93: 134-142. PMID: 36812382, PMCID: PMC10962216, DOI: 10.1097/qai.0000000000003178.Peer-Reviewed Original ResearchConceptsDurable viral suppressionActive public health interventionProportion of PWHPublic health interventionsViral loadCare strategiesHealth interventionsLast viral loadCopies/mLStandard of careRace/ethnicityCare armHIV careViral suppressionAntiretroviral adherenceCD4 categoryExposure categoriesCare individualsPWHCareAge categoriesInterventionTrialsBirth sexRe-Engagement
2022
Rapid Deployment of a Mobile Medical Clinic During the COVID-19 Pandemic: Assessment of Dyadic Maternal-Child Care
Rosenberg J, Sude L, Budge M, León-Martínez D, Fenick A, Altice FL, Sharifi M. Rapid Deployment of a Mobile Medical Clinic During the COVID-19 Pandemic: Assessment of Dyadic Maternal-Child Care. Maternal And Child Health Journal 2022, 26: 1762-1778. PMID: 35900640, PMCID: PMC9330972, DOI: 10.1007/s10995-022-03483-6.Peer-Reviewed Original ResearchConceptsPeople of colorHealth-related social needsQualitative interviewsSocial needsMobile medical clinicCOVID-19 pandemicMother-infant careConstant comparative methodFood insecurityService deliveryMaternal child careMajor themesInterviewsMedical clinicsFamily-centered careInsecurityComparative methodMaternal-infant careMixed-methods observational studyOffice-based visitsAssessment of caregiversInnovative modelSurvey participantsMaternal hypertensionChart reviewPregnant Women and Opioid Use Disorder: Examining the Legal Landscape for Controlling Women's Reproductive Health.
Madden L, Oliva J, Eller A, DiDomizio E, Roosa M, Blanchard L, Kil N, Altice F, Johnson K. Pregnant Women and Opioid Use Disorder: Examining the Legal Landscape for Controlling Women's Reproductive Health. American Journal Of Law & Medicine 2022, 48: 209-222. PMID: 36715261, DOI: 10.1017/amj.2022.26.Peer-Reviewed Original ResearchConceptsOpioid use disorderReproductive healthPregnant womenUse disordersPregnant women's useEvidence-based treatmentsReproductive health outcomesWomen's reproductive healthIntersection of HIVSystems of careHealth care choicesPostpartum womenChild healthTreatment policyUnintentional pregnancyHealth outcomesLarger studyWomenTransactional sexCare choicesMinority womenOutcomesOUDWomen's useDisordersA PrEP Demonstration Project Using eHealth and Community Outreach to Justice-Involved Cisgender Women and Their Risk Networks
Meyer JP, Price CR, Ye Y, Qin Y, Tracey D, Demidont AC, Melbourne K, Altice FL. A PrEP Demonstration Project Using eHealth and Community Outreach to Justice-Involved Cisgender Women and Their Risk Networks. AIDS And Behavior 2022, 26: 3807-3817. PMID: 35672552, DOI: 10.1007/s10461-022-03709-2.Peer-Reviewed Original ResearchConceptsTDF/FTCPrEP care continuumPre-exposure prophylaxisPrimary care providersPrEP demonstration projectRisk network membersNon-Hispanic whitesCisgender womenOutreach modelRespondent-driven samplingPrEP awarenessCommunity outreach modelEnrolled participantsMean ageClinical criteriaIndex participantsCare continuumHIV preventionSocial comorbiditiesCare providersKey populationsPrEPSubstance useMedical insuranceWomenViral Suppression Levels in Men Who Have Sex With Men and Transgender Women With Newly Diagnosed HIV and Alcohol Use Disorder in Peru: Results From a Randomized, Double-Blind, Placebo-Controlled Trial Using Oral Naltrexone
Gonzales P, Bachireddy C, Grieco A, Ding R, de Leon S, Ulrich A, Lama J, Duerr AC, Altice FL. Viral Suppression Levels in Men Who Have Sex With Men and Transgender Women With Newly Diagnosed HIV and Alcohol Use Disorder in Peru: Results From a Randomized, Double-Blind, Placebo-Controlled Trial Using Oral Naltrexone. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2022, 89: 462-471. PMID: 34897226, PMCID: PMC8881312, DOI: 10.1097/qai.0000000000002889.Peer-Reviewed Original ResearchConceptsMSM/transgender womenAlcohol use disorderOral naltrexoneTransgender womenViral suppressionUse disordersEFV/TDF/FTCTreatment of AUDMaximal viral suppressionSingle treatment regimenPlacebo-controlled trialTDF/FTCAntiretroviral therapy adherenceUse of naltrexoneEvidence-based treatmentsViral suppression levelsMVs levelsSecondary outcomesTherapy adherenceLow adherenceAdherence levelsNaltrexoneAUD treatmentHIVPlacebo
2021
Methadone within prison and linkage to and retention in treatment upon community release for people with opioid use disorder in Kyrgyzstan: Evaluation of a national program
Bachireddy C, Shrestha R, Bromberg DJ, Azbel L, Kurmanalieva A, Wegman M, Shumskaya N, Rozanova J, Meyer JP, Altice FL. Methadone within prison and linkage to and retention in treatment upon community release for people with opioid use disorder in Kyrgyzstan: Evaluation of a national program. International Journal Of Drug Policy 2021, 101: 103558. PMID: 34915426, PMCID: PMC9998103, DOI: 10.1016/j.drugpo.2021.103558.Peer-Reviewed Original ResearchConceptsHIV statusMean treatment durationOpioid use disorderPositive HIV statusDuration of treatmentMethadone doseHIV incidenceMethadone servicesMethadone treatmentIndependent correlatesHIV preventionUse disordersTreatment durationMethadoneNational programTreatmentHIVAdministrative dataCommunity releaseMonthsKyrgyz prisonsFirst evaluationIncarcerated peopleDurationReleaseIndividual and poly-substance use and condomless sex among HIV-uninfected adults reporting heterosexual sex in a multi-site cohort
Fredericksen RJ, Whitney BM, Trejo E, Nance RM, Fitzsimmons E, Altice FL, Carrico AW, Cleland CM, Del Rio C, Duerr A, El-Sadr WM, Kahana S, Kuo I, Mayer K, Mehta S, Ouellet LJ, Quan VM, Rich J, Seal DW, Springer S, Taxman F, Wechsberg W, Crane HM, Delaney JAC. Individual and poly-substance use and condomless sex among HIV-uninfected adults reporting heterosexual sex in a multi-site cohort. BMC Public Health 2021, 21: 2002. PMID: 34736425, PMCID: PMC8567631, DOI: 10.1186/s12889-021-12026-7.Peer-Reviewed Original ResearchConceptsLikelihood of CSRecent substance useHIV-negative partnersVaginal sexAnal sexSubstance useHIV-status unknown partnersMultivariable relative risk regressionExposure classificationType of sexHIV-negative adultsPooled effect estimatesPartner's HIV statusMulti-site cohortHigher likelihoodHeterosexual sexRelative risk regressionSingle substance usePoly-substance useHIV-negativeHIV statusRisk regressionPolysubstance useCannabis useSU exposureHIV care continuum among cisgender and transgender women sex workers in Greater Kuala Lumpur, Malaysia
Ranjit YS, Gibson BA, Altice FL, Kamarulzaman A, Azwa I, Wickersham JA. HIV care continuum among cisgender and transgender women sex workers in Greater Kuala Lumpur, Malaysia. AIDS Care 2021, 35: 784-790. PMID: 34723714, PMCID: PMC9056582, DOI: 10.1080/09540121.2021.1995839.Peer-Reviewed Original ResearchConceptsTransgender women sex workersHIV care continuumAntiretroviral treatmentSex workersCare continuumWomen sex workersTransgender womenImportant key populationProportion of womenRespondent-driven sampling studyEvidence-based strategiesAntiretroviral therapyHIV careHIV prevalenceHIV epidemicHIVKey populationsWomenKuala LumpurCisgender womenCount testUnique needsSmall proportionTherapyPopulationAn expanding HIV epidemic among older adults in Ukraine: Implications for patient-centered care
Rozanova J, Zeziulin O, Rich KM, Altice FL, Kiriazova T, Zaviryukha I, Sosidko T, Gulati K, Carroll C, Shenoi SV. An expanding HIV epidemic among older adults in Ukraine: Implications for patient-centered care. PLOS ONE 2021, 16: e0256627. PMID: 34591848, PMCID: PMC8483339, DOI: 10.1371/journal.pone.0256627.Peer-Reviewed Original ResearchConceptsStandardized mortality ratioMortality rateCause standardized mortality ratioTime of diagnosisGeneral population ratesLate-stage HIVAge-matched groupHigh mortality ratePatient-centered careIncident HIVHIV diagnosisHIV testingHIV incidenceHIV treatmentHIV epidemicMortality ratioTreatment strategiesGeneral populationHIVMortality trendsAge groupsEECA countriesTreatment programSame calendar yearOlder peopleSuccessful transfer of stable patients on opioid agonist therapies from specialty addiction treatment to primary care settings in Ukraine: A pilot study
Meteliuk A, Galvez S, Fomenko T, Kalandiia H, Iaryi V, Farnum SO, Islam Z, Altice FL, Madden LM. Successful transfer of stable patients on opioid agonist therapies from specialty addiction treatment to primary care settings in Ukraine: A pilot study. Journal Of Substance Use And Addiction Treatment 2021, 134: 108619. PMID: 34579978, DOI: 10.1016/j.jsat.2021.108619.Peer-Reviewed Original ResearchConceptsOpioid agonist therapyPrimary care clinicsPrimary care settingOAT coverageAgonist therapyStable patientsCare clinicsSubstance useCare settingsNegative urine drug testsSpecialty addictions treatmentUrine drug testsSymptom Identification ScaleMental health symptomsAddiction treatment clinicsHIV transmissionPrimary careTreatment clinicsOAT patientsBASIS-24PatientsHealth symptomsEmotional labilityAddiction treatmentPilot study
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply