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Heping Zhang, PhD

Susan Dwight Bliss Professor of Biostatistics, Professor in the Child Study Center and Professor of Statistics and Data Science; Affiliated Faculty, Yale Institute for Global Health

Contact Information

Heping Zhang, PhD

Office Location

Mailing Address

  • Biostatistics

    PO Box 208034, 60 College Street

    New Haven, CT 06520-8034

    United States



Dr. Zhang published over 360 research articles and monographs in theory and applications of statistical methods and in several areas of biomedical research including epidemiology, genetics, child and women health, mental health, substance use, and reproductive medicine. He directed a training program in mental health research that was funded by the NIMH. He directs the Collaborative Center for Statistics in Science that coordinates the Reproductive Medicine Network to evaluate treatment effectiveness for infertility. He is a fellow of the American Statistical Association and a fellow of the Institute of Mathematical Statistics. He was named the 2008 Myrto Lefokopoulou distinguished lecturer by Harvard School of Public Health and a Medallion Lecturer by the Institute of Mathematical Statistics. In 2011, he received the Royan International Award on Reproductive Health. Dr. Zhang was the president of the International Chinese Statistical Association in 2019. He is a former-editor of the Journal of the American Statistical Association - Applications and Case Studies. He was the recipient of the 2022 Neyman Award and Lecture by the Institute of Mathematical Statistics.

Education & Training

  • Postdoctoral Fellow
    Mathematical Science Research Institute (1991)
  • PhD
    Stanford University (1991)


  • Live Birth After Fresh Embryo Transfer Vs Frozen-thawed Embryo Transfer in Women With Polycystic Ovary Syndrome (FreFro-PCOS)
    Jinan, China (2012-2014)
    From Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of childbearing age. However, the optimal infertility treatment for PCOS patients is still a matter of controversy. Despite producing more follicles and more oocytes than other women undergoing controlled ovarian hyperstimulation during an IVF cycle, women with PCOS have comparable or lower pregnancy rates. Additionally women with PCOS patients undergoing IVF have a higher risk of developing ovarian hyperstimulation syndrome (OHSS), which may be aggravated by pregnancy after an embryo transfer in a fresh cycle. Further women with PCOS are thought to have higher rates of later pregnancy complications including spontaneous abortion, pre-eclampsia, and preterm labor that may be related to impaired implantation in the superovulated endometrium. We propose a randomized clinical trial of elective embryo cryopreservation followed by a programmed cycle of endometrial preparation and frozen embryo transfer (FET) compared to fresh embryo transfer in women with PCOS undergoing in vitro fertilization (IVF).

Honors & Recognition

AwardAwarding OrganizationDate
Neyman Award and LectureInstitute of Mathematical Statistics2022
Royan International Research AwardRoyan Institute2011
Medallion LecturerInstitute of Mathematical Statistics2011
Myrto Lefokopoulou Distinguished LecturerHarvard School of Public Health2008
Fellow, Institute of Mathematical Statistics2006
Independent Scientist Award, NIH/National Institute on Drug Abuse (NIDA)2004
Fellow, American Statistical Association2000
Elected Member, International Statistical Institute1995
FIRST Award, National Institute of Child Health and Human Development1994

Departments & Organizations