Xiaoming Shi
Professor AdjunctCards
About
Research
Publications
2025
Vegetarian diet and likelihood of becoming centenarians in Chinese adults aged 80 years or older: a nested case-control study
Li Y, Wang K, Lv Y, Jigeer G, Huang Y, Shen X, Shi X, Gao X. Vegetarian diet and likelihood of becoming centenarians in Chinese adults aged 80 years or older: a nested case-control study. American Journal Of Clinical Nutrition 2025, 101136. PMID: 41391640, DOI: 10.1016/j.ajcnut.2025.101136.Peer-Reviewed Original ResearchChinese Longitudinal Healthy Longevity SurveyBody mass indexLt;18.5 kg/m2 (uNested Case-Control StudyCase-control studyInverse associationMultivariable unconditional logistic regression modelUnconditional logistic regression modelsProspective nested case-control studyAssociation of vegetarian dietVegetarian dietHigh-quality dietLogistic regression modelsLongevity SurveyOldest-oldChinese adultsPesco-vegetariansMass indexPrimary outcomeIndividuals of advanced ageNon-centenariansRegression modelsAssociation analysisCentenariansFollow-upClimate Change and Health Adaptation: Tailored Interventions are Needed
Bi P, Li T, Li Y, Ban J, Yao X, Shi X. Climate Change and Health Adaptation: Tailored Interventions are Needed. Biomedical And Environmental Sciences 2025, 38: 1351-1353. PMID: 41368958, DOI: 10.3967/bes2025.114.Peer-Reviewed Original ResearchAssociations of changes in social isolation and loneliness with all-cause mortality among older adults: a prospective cohort study
Huang Q, Wei S, Li Z, Lv Y, Shi X, Mao C. Associations of changes in social isolation and loneliness with all-cause mortality among older adults: a prospective cohort study. GeroScience 2025, 1-13. PMID: 41160315, DOI: 10.1007/s11357-025-01971-5.Peer-Reviewed Original ResearchOlder adultsAll-Cause MortalitySocial isolationMortality riskChinese Longitudinal Healthy Longevity SurveyCohort studyAssociated with all-cause mortalityPublic health initiativesPopulation life expectancyExperiences of social isolationAssociation of changesProspective cohort studyCox proportional hazards modelsLongevity SurveyPersistent lonelinessPublic health concernHealth initiativesProportional hazards modelLife expectancyHealth concernHazards modelLonelinessParticipantsAdultsVisit 0Sex-Specific Biological Aging-Related Lipidomic Profiles Mediate the Impact of Urinary Polycyclic Aromatic Hydrocarbon Exposures on Cognitive Function in Healthy Older Adults
Ren H, Shi W, Guo X, Ma X, Zhang J, Situ Y, Li C, Li C, Sun P, Xu Y, Cao K, Qian J, Lu Y, Tong S, Shi X, Tang S. Sex-Specific Biological Aging-Related Lipidomic Profiles Mediate the Impact of Urinary Polycyclic Aromatic Hydrocarbon Exposures on Cognitive Function in Healthy Older Adults. Environment & Health 2025 DOI: 10.1021/envhealth.5c00391.Peer-Reviewed Original ResearchMolecular Atlas of PM2.5 Chemical Constituents on Cardiac Conduction: A Multiomics Landscape in Older Adults
Shi W, Yan W, Wang M, Deng F, Ren H, Gao J, Zhang S, Liu J, Fang J, Wang J, Tong S, Tang S, Shi X. Molecular Atlas of PM2.5 Chemical Constituents on Cardiac Conduction: A Multiomics Landscape in Older Adults. Environmental Science And Technology 2025, 59: 22410-22422. PMID: 41098063, DOI: 10.1021/acs.est.5c05682.Peer-Reviewed Original ResearchConceptsAssociation of PM2.5 wiExposure to PM2.5Ambient fine particulate matterExposure modelPM2.5 chemical constituentsFine particulate matterParticulate matterPbEffect patternsChemical constituentsElemental constituentsS elementsExposureLandscapeEnvironmental originMediation analysisMatterSitesAccumulationIntegrated analysisMultiple pathwaysDMPConstituentsClinical treatment of cardiovascular diseasesReverse mediationCardiorespiratory benefits of reducing indoor particulate matter depend on immune improvements: Insights into individual heterogeneity from a randomized, double-blind crossover trial
Han A, Zhang W, Li L, Yang D, Zhao Y, Liu Q, Wang W, Liu S, Ji X, Shi X, Huang J, Wu S, Zhu T, Guo X, Deng F. Cardiorespiratory benefits of reducing indoor particulate matter depend on immune improvements: Insights into individual heterogeneity from a randomized, double-blind crossover trial. Journal Of Hazardous Materials 2025, 499: 140124. PMID: 41101164, DOI: 10.1016/j.jhazmat.2025.140124.Peer-Reviewed Original ResearchConceptsIndoor particulate matterParticulate matterIndoor PM concentrationsIndoor PM levelsIndoor PM pollutionIndoor air pollutionPM pollutionIndoor PMPM concentrationsPM levelsPM exposureAir pollutionLinear mixed-effects modelsDouble-blind crossover trialCardiorespiratory benefitsMixed-effects modelsPollutionIndividual heterogeneitySystemic immunityCardiovascular benefitsCrossover trialNasal mucosal lining fluidHealthy college studentsMatterMucosal lining fluid[Association of blood selenium exposure with sex hormones among men aged 18-79 years in China].
Li Z, Qu Y, Li Y, Ji S, Song H, Sun Q, Zhang M, Zhang W, Cai J, Ding L, Zhu Y, Zhao F, Cao Z, Lyu Y, Wang L, Shi X. [Association of blood selenium exposure with sex hormones among men aged 18-79 years in China]. Chinese Preventive Medicine 2025, 59: 1632-1639. PMID: 41130758, DOI: 10.3760/cma.j.cn112150-20250420-00333.Peer-Reviewed Original ResearchConceptsMethods: DataTestosterone/estradiol ratioBlood selenium levelsLinear regression modelsResults:Testosterone levelsConfounding factorsSelenium levelsSoy product intakeRegression modelsGeneral demographic characteristicsFasting blood samplesMarital statusSmoking statusDietary frequencyEducation levelAlcohol consumptionEstradiol levelsProduct intakeSerum testosteroneObese menDiabetes statusSubgroup analysisHuman biomonitoring surveyPhysical examinationEvaluation of dried blood spot with inductively coupled plasma mass spectrometry for trace toxic elements measurement in human biomonitoring
Sun Q, Wang Y, Cui W, Yu X, Bai X, Qiu T, Lu Y, Shi X. Evaluation of dried blood spot with inductively coupled plasma mass spectrometry for trace toxic elements measurement in human biomonitoring. Microchemical Journal 2025, 217: 115100. DOI: 10.1016/j.microc.2025.115100.Peer-Reviewed Original ResearchMass spectrometryInductively coupled plasma mass spectrometryInter-batch precisionLow detection limitPlasma mass spectrometryMatrix-matched calibrationDried Blood SpotsICP-MSMatrix effectsSample extraction methodMatrix interferencesDetection limitSatisfactory intra-Excellent linearityInternal standardWorking curveHuman biomonitoringTrace element determinationHuman whole bloodSpectrometryBlood spotsNational human biomonitoring programElement determinationHuman biomonitoring programsField-deployable methodHow a healthy lifestyle mediates socioeconomic inequities in healthy ageing and life expectancies: a 20-year cohort of older adults
Zhou J, Li H, Xia C, Shi W, Wang J, Chen C, Kraus V, Ji J, Lv Y, Chen W, Shi X. How a healthy lifestyle mediates socioeconomic inequities in healthy ageing and life expectancies: a 20-year cohort of older adults. Fundamental Research 2025 DOI: 10.1016/j.fmre.2025.10.004.Peer-Reviewed Original ResearchLow socioeconomic statusHealthy lifestyleSocioeconomic statusOlder adultsSocioeconomic inequalitiesSocioeconomic disparitiesUnhealthy agingYears of healthy life expectancyHealthy agingLife expectancyCohort of older adultsHazard ratioHealthy lifestyle scoreHealthy lifestyle promotionLow-SES populationsTotal life expectancyAssociated with various adverse health outcomesConfidence intervalsHealthy life expectancyHigher socioeconomic statusAdverse health outcomesLifestyle scoreHealth inequalitiesLifestyle promotionHealth disparitiesUrinary Organophosphate Esters and Increased Oxidative Stress in Healthy Older Adults: The China BAPE Study
Li C, Guo X, Ren H, Xu Y, Fang J, Sun P, Ding E, Lu Y, Li C, Zhao X, Long K, Cao K, Qian J, Chen Y, Wang Y, Deng F, Hou M, Shi Y, Cai Y, Tong S, Shen T, Tang S, Shi X. Urinary Organophosphate Esters and Increased Oxidative Stress in Healthy Older Adults: The China BAPE Study. Environment & Health 2025 DOI: 10.1021/envhealth.5c00050.Peer-Reviewed Original ResearchOlder adultsHealthy older adultsOrganophosphate estersAdverse health outcomesGeriatric diseasesDiphenyl phosphateQuantile g-computationGeneralized Additive Mixed ModelsExposure to organophosphate estersBayesian kernel machine regressionHealth hazardsHealth outcomesOPE exposureKernel machine regressionAdditive mixed modelsG-computationDibutyl phosphateBis(1,3-dichloro-2-propyl) phosphate