Erich J Greene, PhD
Research Scientist in BiostatisticsDownloadHi-Res Photo
Cards
Publications Overview
- 48 Publications
- 2,229 Citations
- 21 Yale Co-Authors
Appointments
Biostatistics
Primary
Featured Publication
Estimation of ascertainment bias and its effect on power in clinical trials with time‐to‐event outcomes
Publications Overview
- 48 Publications
- 2,229 Citations
- 21 Yale Co-Authors
Appointments
Biostatistics
Primary
Featured Publication
Estimation of ascertainment bias and its effect on power in clinical trials with time‐to‐event outcomes
Publications Overview
- 48 Publications
- 2,229 Citations
- 21 Yale Co-Authors
Appointments
Biostatistics
Primary
Featured Publication
Estimation of ascertainment bias and its effect on power in clinical trials with time‐to‐event outcomes
About
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Titles
Research Scientist in Biostatistics
Biography
Erich Greene is a biostatistician and statistical programmer at the Yale Center for Analytical Sciences (YCAS) and the Yale Data Coordinating Center (YDCC), working primarily with clinical trial monitoring, analysis, and methodology in roles ranging from front-line biostatistician to DCC PI. He holds a master's in physics from Cornell, a doctorate in psychology from Princeton, and a fondness for the serial comma.
Last Updated on October 13, 2025.
Appointments
Biostatistics
Research ScientistPrimary
Other Departments & Organizations
Education & Training
- PhD
- Princeton University, Psychology (2003)
- MA
- Princeton University, Psychology (1997)
- MS
- Cornell University, Physics (1995)
- AB
- Princeton University, Physics (1991)
Research
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Overview
Medical Research Interests
Biostatistics; Clinical Trial; Data Interpretation, Statistical; Mathematical Computing; Models, Statistical; Pragmatic Clinical Trial; Statistics
Public Health Interests
Bioinformatics; Clinical Trials; Modeling; Randomized Trials; Statistical Computing; Survival Analysis
ORCID
0000-0002-9473-830X
Research at a Glance
Yale Co-Authors
Frequent collaborators of Erich J Greene's published research.
Publications Timeline
A big-picture view of Erich J Greene's research output by year.
Research Interests
Research topics Erich J Greene is interested in exploring.
James Dziura, MPH, PhD
Can Meng, MS, MPH
Thomas M. Gill, MD
David Ganz
Denise Esserman, PhD
Peter Peduzzi, PhD
48Publications
2,229Citations
Models, Statistical
Publications
Featured Publications
Estimation of ascertainment bias and its effect on power in clinical trials with time‐to‐event outcomes
Greene EJ, Peduzzi P, Dziura J, Meng C, Miller ME, Travison TG, Esserman D. Estimation of ascertainment bias and its effect on power in clinical trials with time‐to‐event outcomes. Statistics In Medicine 2020, 40: 1306-1320. PMID: 33316841, PMCID: PMC9007163, DOI: 10.1002/sim.8842.Peer-Reviewed Original ResearchCitationsA SAS Macro for Covariate-Constrained Randomization of General Cluster-Randomized and Unstratified Designs.
Greene EJ. A SAS Macro for Covariate-Constrained Randomization of General Cluster-Randomized and Unstratified Designs. Journal Of Statistical Software 2017, 77 PMID: 28649186, PMCID: PMC5479642, DOI: 10.18637/jss.v077.c01.Peer-Reviewed Original ResearchCitationsAltmetricSimulating time-to-event data subject to competing risks and clustering: A review and synthesis
Meng C, Esserman D, Li F, Zhao Y, Blaha O, Lu W, Wang Y, Peduzzi P, Greene E. Simulating time-to-event data subject to competing risks and clustering: A review and synthesis. Statistical Methods In Medical Research 2022, 32: 305-333. PMID: 36412111, PMCID: PMC11654122, DOI: 10.1177/09622802221136067.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsHealth System, Community-Based, or Usual Dementia Care for Persons With Dementia and Caregivers
Reuben D, Gill T, Stevens A, Williamson J, Volpi E, Lichtenstein M, Jennings L, Galloway R, Summapund J, Araujo K, Bass D, Weitzman L, Tan Z, Evertson L, Yang M, Currie K, Green A, Godoy S, Abraham S, Reese J, Samper-Ternent R, Hirst R, Borek P, Charpentier P, Meng C, Dziura J, Xu Y, Skokos E, He Z, Aiudi S, Peduzzi P, Greene E, Serrano K, Unger E, Arruda L, Bautista L, Callahan C, Maslow K, Ling S, Bonner A, Pace D, Cherry D, Kremer I, Nicholson B, Stephens C, Hendler R, Carnie M, Shelton A, Mignosa B, Funaro B, Eisenmann K, Lu C, Chattopadhyay S, Rhoades D, Lakomski A, Maher D, McCurry D, Williamson S, Moyer S, Robertson L, Tilles A, Battle L, Walker W, Levine S, Knight G, Eaton A, Rose T, Weston E, Orr B, Lang S, Rinaldi S, Shore J, Garboczi L, Phoenix K, Mitchell M, Levan L, Layza M, Musgrave D, Silverman J, Martin A, Nienstedt J, Handoo R, Woolard N, Burcombe D, Hutchens C, Sanghi S, Ocloo A, Essiet S, Shah M, Bartosh H, Banda J, Birchfield T, Roznos T, Collins B, Parker D, Matlock M, Drew L, Jones T, Hill B, Walker J, Wills J, Andrews M, Kroloff S, Brown G, Franz C, Perez G, Castillo E, Flores C, Raji M, Martinez E, Skinkis P, Williams A, Minello S, Sherrod J, Odejimi A, Lockhart M, McDonald A, Gibson D, Tobias N, Spetter K, Finney G, Ladd I, Weaver K, Nicoletto P, Smith D, DeLucca R, Delmar N, Dopko J, Patel M, Berry P, Zimmerman K, Fasciana J, Hendricks L, Freedman K, Gudonis S, Drutarovsky H, Gurzynski A, Shillabeer M, Shipsky K, Cannon C, Rahm A, Sharf L, Kearney K, Liu J, Keeler E, Ruder T. Health System, Community-Based, or Usual Dementia Care for Persons With Dementia and Caregivers. JAMA 2025, 333: 950-961. PMID: 39878968, PMCID: PMC11780506, DOI: 10.1001/jama.2024.25056.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCommunity-based careModified Caregiver Strain IndexHealth system-basedCaregiver Strain IndexCaregiver self-efficacyUsual careDementia careHealth systemCommunity-BasedNPI-QPrimary outcomeApproaches to dementia careCommunity-based dementia careCommunity-based care interventionsSelf-EfficacyDementia care programDementia care specialistsSecondary outcomesStrain indexSystem-based careCommunity-dwelling personsNeuropsychiatric Inventory QuestionnairePatient behavioral symptomsNPI-Q scoresCaregiver outcomesA Randomized Trial of a Multifactorial Strategy to Prevent Serious Fall Injuries
Bhasin S, Gill TM, Reuben DB, Latham NK, Ganz DA, Greene EJ, Dziura J, Basaria S, Gurwitz JH, Dykes PC, McMahon S, Storer TW, Gazarian P, Miller ME, Travison TG, Esserman D, Carnie MB, Goehring L, Fagan M, Greenspan SL, Alexander N, Wiggins J, Ko F, Siu AL, Volpi E, Wu AW, Rich J, Waring SC, Wallace RB, Casteel C, Resnick NM, Magaziner J, Charpentier P, Lu C, Araujo K, Rajeevan H, Meng C, Allore H, Brawley BF, Eder R, McGloin JM, Skokos EA, Duncan PW, Baker D, Boult C, Correa-de-Araujo R, Peduzzi P. A Randomized Trial of a Multifactorial Strategy to Prevent Serious Fall Injuries. New England Journal Of Medicine 2020, 383: 129-140. PMID: 32640131, PMCID: PMC7421468, DOI: 10.1056/nejmoa2002183.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSerious fall injuriesFall injuriesIntervention groupControl groupUsual careMultifactorial interventionRate of hospitalizationPrimary care practicesCluster-randomized trialCommunity-dwelling adultsFirst-event analysisYears of ageHealth care systemRate of fallElectronic health recordsBaseline characteristicsPrimary outcomeRandomized trialsMean ageEfficacy trialsIndividualized planCare practicesInjuryMultifactorial strategyEvent ratesEffect of a Multifactorial Fall Injury Prevention Intervention on Patient Well‐Being: The STRIDE Study
Gill TM, Bhasin S, Reuben DB, Latham NK, Araujo K, Ganz DA, Boult C, Wu AW, Magaziner J, Alexander N, Wallace RB, Miller ME, Travison TG, Greenspan SL, Gurwitz JH, Rich J, Volpi E, Waring SC, Manini TM, Min LC, Teresi J, Dykes PC, McMahon S, McGloin JM, Skokos EA, Charpentier P, Basaria S, Duncan PW, Storer TW, Gazarian P, Allore HG, Dziura J, Esserman D, Carnie MB, Hanson C, Ko F, Resnick NM, Wiggins J, Lu C, Meng C, Goehring L, Fagan M, Correa‐de‐Araujo R, Casteel C, Peduzzi P, Greene EJ. Effect of a Multifactorial Fall Injury Prevention Intervention on Patient Well‐Being: The STRIDE Study. Journal Of The American Geriatrics Society 2020, 69: 173-179. PMID: 33037632, PMCID: PMC8178516, DOI: 10.1111/jgs.16854.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSerious fall injuriesFall injuriesMultifactorial interventionPhysical functionOutcomes Measurement Information System (PROMIS) AnxietyLeast square mean changePragmatic cluster-randomized trialMean scoreCommunity-living personsIntervention group's mean scoreInjury prevention interventionsPrimary care practicesFalls Efficacy ScaleCluster-randomized trialUsual careElders StudyDisability InstrumentSTRIDE studyDepression ScaleMean changePrevention interventionsHigh riskCare practicesControl groupMeaningful improvementsAssociation of Racial Disparities With Access to Kidney Transplant After the Implementation of the New Kidney Allocation System
Kulkarni S, Ladin K, Haakinson D, Greene E, Li L, Deng Y. Association of Racial Disparities With Access to Kidney Transplant After the Implementation of the New Kidney Allocation System. JAMA Surgery 2019, 154: 618-625. PMID: 30942882, PMCID: PMC6583835, DOI: 10.1001/jamasurg.2019.0512.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsDeceased donor transplantsKidney allocation systemDonor transplantsKidney transplantTransplant probabilityDeath/Race/ethnicityHispanic individualsWhite individualsOrgan procurementBlack individualsNew kidney allocation systemRetrospective cohort studyWait-listed patientsKidney transplant databaseStatus changesAntibody categoriesLevel of sensitizationInactive statusInactive patientsTransplant databaseTransplant outcomesCohort studyMedian ageAntibody groupSex Differences in Symptom Phenotypes Among Patients With Acute Myocardial Infarction
Brush JE, Krumholz HM, Greene EJ, Dreyer RP. Sex Differences in Symptom Phenotypes Among Patients With Acute Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2020, 13: e005948. PMID: 32063049, PMCID: PMC7041412, DOI: 10.1161/circoutcomes.119.005948.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsAdolescentAdultBiological Variation, IndividualFemaleHealth Status DisparitiesHumansInterviews as TopicMaleMiddle AgedMyocardial InfarctionPatient AdmissionPhenotypePredictive Value of TestsProspective StudiesRisk AssessmentRisk FactorsSex FactorsSpainSymptom AssessmentUnited StatesYoung AdultConceptsAcute myocardial infarctionMyocardial infarctionMedical recordsYoung womenDiagnosis of AMIObservational cohort studyMedical record abstractionSymptom phenotypeDiagnostic processAnalysis of symptomsVIRGO StudyCohort studyRecord abstractionIndividual patientsClinician's abilityDiagnosis rateStandardized interviewPhenotype subgroupsSymptomsSimilar findingsYoung adultsWomenMenInfarctionPatients
2025
Patient and Caregiver Outcomes of Health System, Community-Based, and Usual Dementia Care
Reuben D, Stevens A, Gill T, Williamson J, Volpi E, Lichtenstein M, Jennings L, Galloway R, Summapund J, Araujo K, Bass D, Weitzman L, Tan Z, Evertson L, Yang M, Green A, Samper-Ternent R, Borek P, Xu Y, Peduzzi P, Greene E, Serrano K, Unger E, Arruda L, Bautista L, Callahan C, Maslow K, Ling S, Bonner A, Pace D, Cherry D, Kremer I, Nicholson B, Stephens C, Hendler R, Carnie M, Shelton A, Mignosa B, Funaro B, Eisenmann K, Lu C, Chattopadhyay S, Rhoades D, Lakomski A, Maher D, McCurry D, Williamson S, Moyer S, Robertson L, Tilles A, Battle L, Walker W, Levine S, Knight G, Eaton A, Rose T, Weston E, Orr B, Lang S, Rinaldi S, Shore J, Garboczi L, Phoenix K, Mitchell M, Levan L, Layza M, Musgrave D, Silverman J, Martin A, Nienstedt J, Handoo R, Woolard N, Burcombe D, Hutchens C, Sanghi S, Ocloo A, Essiet S, Shah M, Bartosh H, Banda J, Birchfield T, Roznos T, Collins B, Parker D, Matlock M, Drew L, Jones T, Hill B, Walker J, Wills J, Andrews M, Kroloff S, Brown G, Franz C, Perez G, Castillo E, Flores C, Raji M, Martinez E, Skinkis P, Williams A, Minello S, Sherrod J, Odejimi A, Lockhart M, McDonald A, Gibson D, Tobias N, Spetter K, Finney G, Ladd I, Weaver K, Nicoletto P, Smith D, DeLucca R, Delmar N, Dopko J, Patel M, Berry P, Zimmerman K, Fasciana J, Hendricks L, Freedman K, Gudonis S, Drutarovsky H, Gurzynski A, Shillabeer M, Shipsky K, Cannon C, Rahm A, Sharf L, Kearney K, Liu J, Keeler E, Ruder T, Ditch L. Patient and Caregiver Outcomes of Health System, Community-Based, and Usual Dementia Care. JAMA Internal Medicine 2025, 185: 1227-1236. PMID: 40892399, PMCID: PMC12406143, DOI: 10.1001/jamainternmed.2025.4247.Peer-Reviewed Original ResearchCitationsAltmetricConceptsCommunity-based dementia careDementia caregiving dyadsDementia careOverall caregiver burdenUsual careQuality of careCaregiver outcomesQuality of lifeCaregiver burdenCaregiver satisfactionCaregiver ratingsRatings of quality of careComprehensive dementia care programPositive Aspects of CaregivingFunctional statusDementia care programDementia care studiesSatisfaction with careAspects of caregivingRandomized clinical trialsPositive aspectsNurse practitionersCaregiver measuresPhysician assistantsCare programStatistical considerations for evaluating treatment effect under various non-proportional hazard scenarios
Zhang X, Greene E, Blaha O, Wei W. Statistical considerations for evaluating treatment effect under various non-proportional hazard scenarios. Statistical Methods In Medical Research 2025, 34: 986-1000. PMID: 39930911, DOI: 10.1177/09622802241313297.Peer-Reviewed Original ResearchAltmetricConceptsNon-proportional hazardsType I error rateAnalysis of time-to-event outcomesTime-to-event outcomesComparison of statistical methodsGeneralized gamma modelMaxCombo testGamma modelF modelOverall treatment effectTreatment effectsReal dataSurvival probabilityGeneralizationOncology trialsPublished oncology trials
Academic Achievements & Community Involvement
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activity BMC Medical Research Methodology
2023 - PresentJournal ServiceRevieweractivity BMJ Open
2022 - PresentJournal ServiceRevieweractivity Computer Methods and Programs in Biomedicine
2021 - PresentJournal ServiceRevieweractivity JACC: Advances
2024 - PresentJournal ServiceRevieweractivity Journal of Gerontology: Medical Science
2022 - PresentJournal ServiceReviewer
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