Kendra Plourde, PhD
Assistant Professor of BiostatisticsDownloadHi-Res Photo
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Appointments
Biostatistics
Primary
Contact Info
Education
PhD
Boston University, Biostatistics (2020)
Boston University, Biostatistics (2020)
MA
Boston University, Biostatistics (2014)
Boston University, Biostatistics (2014)
BA
Northwestern University, Mathematics (2010)
Northwestern University, Mathematics (2010)
Appointments
Biostatistics
Primary
Contact Info
Education
PhD
Boston University, Biostatistics (2020)
Boston University, Biostatistics (2020)
MA
Boston University, Biostatistics (2014)
Boston University, Biostatistics (2014)
BA
Northwestern University, Mathematics (2010)
Northwestern University, Mathematics (2010)
Appointments
Biostatistics
Primary
Contact Info
Education
PhD
Boston University, Biostatistics (2020)
Boston University, Biostatistics (2020)
MA
Boston University, Biostatistics (2014)
Boston University, Biostatistics (2014)
BA
Northwestern University, Mathematics (2010)
Northwestern University, Mathematics (2010)
About
Titles
Assistant Professor of Biostatistics
Biography
Kendra Plourde earned her PhD in Biostatistics at Boston University in 2020, and joined the Yale School of Public Health faculty in 2022 as an Assistant Professor of Biostatistics after completing a postdoc at Yale. Her methodological research interests are in the design and analysis of observational studies and randomized controlled trials with correlated data, for example, longitudinal studies, cluster randomized and stepped wedge designs with complex sources of clustering, and clinical trials with multivariate outcomes. Her collaborative research interests are in studies of Alzheimer's disease and related dementias and aging. Kendra is also a member of the Yale Center for Analytical Sciences and a collaborator with the Yale Program on Aging.
Appointments
Biostatistics
Assistant ProfessorPrimary
Other Departments & Organizations
Education & Training
- Postdoctoral Associate
- Yale University
- PhD
- Boston University, Biostatistics (2020)
- MA
- Boston University, Biostatistics (2014)
- BA
- Northwestern University, Mathematics (2010)
Research
Overview
Public Health Interests
Randomized Trials; Modeling; Epidemiology Methods; Aging; Clinical Trials
ORCID
0000-0001-6654-0710
Research at a Glance
Yale Co-Authors
Frequent collaborators of Kendra Plourde's published research.
Publications Timeline
A big-picture view of Kendra Plourde's research output by year.
Fan Li, PhD
Guangyu Tong, PhD
Robert Becher, MD, MS, FACS
Thomas M. Gill, MD
Brent Vander Wyk, PhD
Can Meng, MS, MPH
37Publications
1,442Citations
Publications
2025
Novel indices of state- and county-level social disadvantage in older Americans and disparities in mortality
Wang Y, Zang E, Davis-Plourde K, Gill T, Becher R. Novel indices of state- and county-level social disadvantage in older Americans and disparities in mortality. Health & Place 2025, 92: 103438. PMID: 40058245, DOI: 10.1016/j.healthplace.2025.103438.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsIncreased mortality riskContextual disadvantageOlder personsOlder AmericansCommunity-living older personsSocial disadvantageMortality riskIndices of social disadvantageReduce health disparitiesPopulation of older AmericansCounty-levelPublic health policiesNon-disadvantaged groupsMortality disparitiesHealth disparitiesHealth policyMortality existUnited StatesDisadvantaged countiesNegative binomial modelGeriatric populationComposite indexDisparitiesDisadvantaged statesMultidimensional factorsIncomplete Ascertainment of Mortality in a Nationally Representative Longitudinal Study of Community-Living Older Americans
Gill T, Liang J, Vander Wyk B, Leo-Summers L, Wang Y, Becher R, Davis-Plourde K. Incomplete Ascertainment of Mortality in a Nationally Representative Longitudinal Study of Community-Living Older Americans. The Journals Of Gerontology Series A 2025, glaf014. PMID: 39823281, DOI: 10.1093/gerona/glaf014.Peer-Reviewed Original ResearchAltmetricConceptsNational Health and Aging Trends StudyAscertainment of mortalityIncomplete ascertainmentLongitudinal studies of older personsStudy of older personsNationally representative longitudinal studyIncidence rate ratiosLoss to follow-upMortality incidence ratesYear of deathLongitudinal studyRepresentative longitudinal studyCommunity-livingTrends StudyOlder personsRecommended strategiesMedicare dataRate ratiosCumulative mortality rateIncidence rateResults of longitudinal analysesAscertainmentEvaluate mortalityLongitudinal analysisDecedents
2024
A review of current practice in the design and analysis of extremely small stepped-wedge cluster randomized trials
Tong G, Nevins P, Ryan M, Davis-Plourde K, Ouyang Y, Macedo J, Meng C, Wang X, Caille A, Li F, Taljaard M. A review of current practice in the design and analysis of extremely small stepped-wedge cluster randomized trials. Clinical Trials 2024, 22: 45-56. PMID: 39377196, PMCID: PMC11810615, DOI: 10.1177/17407745241276137.Peer-Reviewed Original ResearchCitationsAltmetricConceptsSmall-sample correctionsStepped-wedge cluster randomized trialCluster randomized trialSample size calculation methodGeneralized linear mixed modelsLongitudinal correlation structureSize calculation methodLinear mixed modelsPermutation testSample sizeBayesian approachRandomized trialsCorrelation structureMixed modelsBayesian analysisGeneralized estimating equationsPermutationMedian sample sizeIntervention conditionRandomization methodEquationsNational Estimates of Short- and Longer-Term Hospital Readmissions After Major Surgery Among Community-Living Older Adults
Wang Y, Leo-Summers L, Vander Wyk B, Davis-Plourde K, Gill T, Becher R. National Estimates of Short- and Longer-Term Hospital Readmissions After Major Surgery Among Community-Living Older Adults. JAMA Network Open 2024, 7: e240028. PMID: 38416499, PMCID: PMC10902728, DOI: 10.1001/jamanetworkopen.2024.0028.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCenters for Medicare & Medicaid ServicesFee-for-serviceMedicare Advantage beneficiariesHospital readmissionUS residentsNational Health and Aging Trends Study dataCommunity-living older adultsProspective longitudinal cohort studyCommunity-living participantsRate of hospital readmissionLikelihood of hospital readmissionPopulation-based estimatesNationally representative estimatesSex-adjusted modelsCommunity-livingData linkageGeriatric conditionsMedicaid ServicesOlder personsOlder adultsMain OutcomesNational estimatesRepresentative estimatesData analysisCohort study
2023
Adherence to key recommendations for design and analysis of stepped-wedge cluster randomized trials: A review of trials published 2016–2022
Nevins P, Ryan M, Davis-Plourde K, Ouyang Y, Macedo J, Meng C, Tong G, Wang X, Ortiz-Reyes L, Caille A, Li F, Taljaard M. Adherence to key recommendations for design and analysis of stepped-wedge cluster randomized trials: A review of trials published 2016–2022. Clinical Trials 2023, 21: 199-210. PMID: 37990575, PMCID: PMC11003836, DOI: 10.1177/17407745231208397.Peer-Reviewed Original ResearchCitationsAltmetricAssessment of Regional Nursing Home Preparedness for and Regulatory Responsiveness to Wildfire Risk in the Western US
Festa N, Throgmorton K, Davis-Plourde K, Dosa D, Chen K, Zang E, Kelly J, Gill T. Assessment of Regional Nursing Home Preparedness for and Regulatory Responsiveness to Wildfire Risk in the Western US. JAMA Network Open 2023, 6: e2320207. PMID: 37358851, PMCID: PMC10293909, DOI: 10.1001/jamanetworkopen.2023.20207.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCross-sectional studyNursing homesNursing home characteristicsMean survival timeUS nursing homesGreater mean numberPrimary outcomeUS CentersExposure statusMAIN OUTCOMEElevated riskSurvival timeSurvival analysisPresence of deficienciesMore deficienciesRisk statusEmergency preparednessHome characteristicsMean numberRiskPreparedness standardsDeficiencyResponsivenessHigh percentageOutcomesA scoping review described diversity in methods of randomization and reporting of baseline balance in stepped-wedge cluster randomized trials
Nevins P, Davis-Plourde K, Pereira Macedo J, Ouyang Y, Ryan M, Tong G, Wang X, Meng C, Ortiz-Reyes L, Li F, Caille A, Taljaard M. A scoping review described diversity in methods of randomization and reporting of baseline balance in stepped-wedge cluster randomized trials. Journal Of Clinical Epidemiology 2023, 157: 134-145. PMID: 36931478, PMCID: PMC10546924, DOI: 10.1016/j.jclinepi.2023.03.010.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsStepped-wedge clusterIndividual-level characteristicsMethod of randomizationCross-sectional designControl armBaseline imbalancesCohort designMedian numberElectronic searchPrimary analysisBaseline balanceStudy designPrimary reportsBaselineTrialsIntervention conditionSW-CRTsRandomizationReporting
2022
Power analyses for stepped wedge designs with multivariate continuous outcomes
Davis‐Plourde K, Taljaard M, Li F. Power analyses for stepped wedge designs with multivariate continuous outcomes. Statistics In Medicine 2022, 42: 559-578. PMID: 36565050, PMCID: PMC9985483, DOI: 10.1002/sim.9632.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMultivariate outcomesMultivariate linear mixed modelIntracluster correlation coefficientSample size proceduresClosed cohort designRigorous justificationSample size calculation procedureTreatment effect estimatorJoint distributionSize proceduresTest statisticLinear mixed modelsEfficient treatment effect estimatorsCommon treatment effectMixed modelsCalculation procedureExtensive simulationsEffects estimatorIntersection-union testPower analysisEstimatorWedge designEfficient powerModelContinuous outcomesNon-Alcoholic Fatty Liver Disease, Liver Fibrosis, and Regional Amyloid-β and Tau Pathology in Middle-Aged Adults: The Framingham Study
Weinstein G, O’Donnell A, Davis-Plourde K, Zelber-Sagi S, Ghosh S, DeCarli CS, Thibault EG, Sperling RA, Johnson KA, Beiser AS, Seshadri S. Non-Alcoholic Fatty Liver Disease, Liver Fibrosis, and Regional Amyloid-β and Tau Pathology in Middle-Aged Adults: The Framingham Study. Journal Of Alzheimer's Disease 2022, 86: 1371-1383. PMID: 35213373, PMCID: PMC11323287, DOI: 10.3233/jad-215409.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsNon-alcoholic fatty liver diseasePrevalent non-alcoholic fatty liver diseaseFIB-4 indexFatty liver diseaseAlzheimer's disease pathologyFIB-4Liver fibrosisDisease pathologyAdvanced fibrosisLiver diseaseTau pathologyRisk factorsRelationship of NAFLDTau positron emission tomography (PET) imagingEarly Alzheimer's disease pathologyCardio-metabolic risk factorsAlcoholic fatty liver diseaseThird Generation cohortsFramingham Study participantsNon-invasive indexPositron emission tomography (PET) imagingEmission Tomography ImagingMiddle-aged adultsRegional tauLiver steatosisJoint Models for Estimating Determinants of Cognitive Decline in the Presence of Survival Bias
Davis-Plourde KL, Mayeda ER, Lodi S, Filshtein T, Beiser A, Gross AL, Seshadri S, Glymour MM, Tripodis Y. Joint Models for Estimating Determinants of Cognitive Decline in the Presence of Survival Bias. Epidemiology 2022, 33: 362-371. PMID: 35383644, DOI: 10.1097/ede.0000000000001472.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCognitive declineSurvival biasCox proportional hazards modelHazard of mortalityProportional hazards modelExposure of interestEffect of educationEffects of exposureHazards modelDementia diagnosisAlzheimer's diseaseMixed-effects modelsGEE modelMortalitySurvivalInconsistent resultsDiseaseInformative attritionStudy dataAttrition weightsExposure