2023
Pulmonary Function and Quality of Life in Aging Men With and Without HIV from the Multicenter AIDS Cohort Study
Abdo M, Kunisaki K, Morris A, Stosor V, Chang D, D'Souza G, Crothers K, Abdel-Maksoud M, DiGuiseppi C, Brown T, Erlandson K, MaWhinney S. Pulmonary Function and Quality of Life in Aging Men With and Without HIV from the Multicenter AIDS Cohort Study. AIDS Research And Human Retroviruses 2023, 39: 621-632. PMID: 37276144, PMCID: PMC10712368, DOI: 10.1089/aid.2023.0001.Peer-Reviewed Original ResearchConceptsPulmonary impairmentPulmonary functionOdds ratioMedian age 57 yearsMulticenter AIDS Cohort StudyGreater respiratory impairmentPulmonary function impairmentImpaired pulmonary functionAge 57 yearsHealth-related qualityLower physical HRQoLRespiratory health statusAIDS Cohort StudyCohort study dataQuality of lifeHRQoL scoresCohort studyLower HRQoLPhysical HRQoLHIV serostatusAdjusted analysisFunction impairmentRespiratory impairmentMmHg decreaseRespiratory health
2022
Regional Differences in Risk of Recurrent Falls Among Older U.S. Women and Men with HIV in the HIV Infection, Aging, and Immune Function Long-Term Observational Study
Abdo M, Wu X, Sharma A, Tassiopoulos KK, Brown TT, Koletar SL, Yin MT, Erlandson KM. Regional Differences in Risk of Recurrent Falls Among Older U.S. Women and Men with HIV in the HIV Infection, Aging, and Immune Function Long-Term Observational Study. AIDS Research And Human Retroviruses 2022, 38: 530-537. PMID: 35018800, PMCID: PMC9297325, DOI: 10.1089/aid.2021.0162.Peer-Reviewed Original ResearchConceptsRecurrent fallsPhysical activityOlder PWHHigher oddsWomen's Interagency HIV StudyBody mass indexLong-term observational studyHigh physical activityOlder U.S. womenLogistic regression modelsSemiannual visitsMultinomial logistic regression modelsHIV infectionMedian ageStudy entryMultivariable analysisObese individualsHIV StudyEffect modificationObservational studyFall assessmentGeographic regionsU.S. womenGreater riskHIV
2021
A Unique Gut Microbiome–Physical Function Axis Exists in Older People with HIV: An Exploratory Study
Dillon SM, Abdo MH, Wilson MP, Liu J, Jankowski CM, Robertson CE, Tuncil Y, Hamaker B, Frank DN, MaWhinney S, Wilson CC, Erlandson KM. A Unique Gut Microbiome–Physical Function Axis Exists in Older People with HIV: An Exploratory Study. AIDS Research And Human Retroviruses 2021, 37: 542-550. PMID: 33787299, PMCID: PMC8260890, DOI: 10.1089/aid.2020.0283.Peer-Reviewed Original ResearchConceptsPhysical functionOlder PWHOlder personsMuscle functionLean massLower short physical performance battery scoresBody compositionShort Physical Performance Battery scoreLower extremity muscle functionPhysical Performance Battery scoreGut microbiomeStool SCFA levelsEffective antiretroviral therapyPhysical function measurementsBetter muscle functionFunction axisAntiretroviral therapySCFA levelsHIV serostatusSPPB scoreUninfected personsSCFA butyrateGrip strengthUninfected controlsPWH
2017
Frailty is strongly associated with increased risk of recurrent falls among older HIV-infected adults
Tassiopoulos K, Abdo M, Wu K, Koletar SL, Palella FJ, Kalayjian R, Taiwo B, Erlandson KM. Frailty is strongly associated with increased risk of recurrent falls among older HIV-infected adults. AIDS 2017, 31: 2287-2294. PMID: 28991026, PMCID: PMC5654616, DOI: 10.1097/qad.0000000000001613.Peer-Reviewed Original ResearchConceptsRecurrent fallsFrailty assessmentGrip strengthSelf-reported weight lossLogistic regressionContribution of frailtyMulticenter cohort studyLow physical activityRisk of fallsPotential target populationOlder HIVCohort studyBaseline frailtyPeripheral neuropathyEffect modificationFrail individualsMultivariable modelFrail personsPhysical activityClinical careMultinomial logistic regressionHIVNonfrail individualsPrefrailSignificant association