# Read ME ge-int

Thank you for your interest in our work. Please find the Fortran program and a brief explanatory text attached to this message. To compile the program, if you are in a unix environment, and have Fortran 77, type "f77 ge_int.f -o ge_int". You can then call the program by "ge_int". Please report any problems you experience with the program to me. For notations and assumptions, please refer to "ge_int.txt", as well as to Foppa I, Spiegelman D. AJE 1997; 146:596-604. I also include the non-interactive version of the program ("ge_intn.f"). If you are on unix, the program can be run (after having been compiled as described above) by ge_intn < data > out where data is the name of the input file and out is the output file. For power calculations, for example, the input file has the form: p 3 5 .2 2 200 1.5 1.5 2 5 .3 2 200 1.5 1.5 2 5 .4 2 200 1.5 1.5 2 "p" stands for power calculation and 3 is the number of lines (i.e. calculations). The numbers of the follwoing lines correspond to: number of quantiles, gene prevalence, control-case ratio, number of cases, OR(E|G=0)^(k-1) (top-to-bottom contrast), OR(G|E=0), (OR(E|G=1)/OR(E|G=0))^(k-1) (to-to-bottom contrast). If you want to do sample size calculations, use the form s 3 .9 5 .2 2 1.5 1.5 2 .8 5 .3 2 1.5 1.5 2 .7 5 .4 2 1.5 1.5 2 where "s" refers to sample size calculations, and the following lines correspond to: power to be achieved, number of quantiles, gene prevalence, control-case ratio, OR(E|G=0)^(k-1) (top-to-bottom contrast), OR(G|E=0), (OR(E|G=1)/OR(E|G=0))^(k-1) (to-to-bottom contrast). If you wish to receive a compiled version of the program for dos, please let me know. If you have any further questions, don't hesitate to contact me. Sincerely, Ivo Foppa