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Qualitative Comparative Analysis: Applying to Research on Public Health Interventions

February 14, 2024
  • 00:01<v Presenter>I'm an Associate Professor of Epidemiology</v>
  • 00:04at the Yale School of Public Health,
  • 00:05as well as the school's Associate Dean
  • 00:07for Diversity, Equity and Inclusion.
  • 00:10It is my pleasure to step in
  • 00:12for Professor Donna Spiegelman today
  • 00:14to introduce our speaker, Dr. Lingrui Liu.
  • 00:18Before I do that though,
  • 00:20I'd like to acknowledge that today's seminar is sponsored
  • 00:22by both the Yale Center for Methods and Implementation
  • 00:25and Prevention Science, or CMIPS
  • 00:28and the Yale Center for Implementation Science.
  • 00:31Based at the Yale School of Health,
  • 00:33CMIPS develops and disseminates
  • 00:35innovative methodological approaches
  • 00:38to address implementation gaps
  • 00:40and improve public health worldwide,
  • 00:43strategically selecting the issues
  • 00:45that carry the greatest burden and hold the greatest promise
  • 00:48for amelioration right now.
  • 00:50If you would like to be informed
  • 00:52about future CMIPS seminars,
  • 00:54please let William Tutle know in the chat
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  • 01:00Based at the Yale School of Medicine,
  • 01:02YCIS accelerates the late stage translation
  • 01:06of evidence-based treatments, practices and policies
  • 01:09to improve the health
  • 01:10of the residents of New Haven and beyond.
  • 01:13Its Yale Scholars and Implementation Science,
  • 01:15or YSIS program is the training core of the center.
  • 01:19YCIS is funded by a five-year
  • 01:21National Heart, Lung and Blood Institute K-12 award
  • 01:24and is designed to train junior faculty
  • 01:27and postdoctoral fellows
  • 01:28in late stage dissemination and implementation science.
  • 01:33Turning to our speaker today,
  • 01:35Dr. Lingrui Liu is an associate research scientist
  • 01:38in the Department of Health Policy and Management at YSPH
  • 01:42as well as a K-12 EL Scholar Implementation Science
  • 01:45at the Yale Center for Implementation Science
  • 01:48and a fellow at CMIPS.
  • 01:51Her research focuses on healthcare management
  • 01:54and organizational studies, healthcare systems,
  • 01:57quality improvement, patient safety,
  • 02:00decision science and implementation science.
  • 02:03Dr. Liu received has received national recognition
  • 02:07for her work, including awards
  • 02:08from the Academy of Management and Academy Health.
  • 02:12Dr. Liu received her doctorate from Harvard University
  • 02:15in Health Systems, Economics and Decision Science.
  • 02:19The title of her talk today is,
  • 02:20"Qualitative Comparative Analysis:
  • 02:22Applying to Research on Public Health Interventions."
  • 02:26Welcome Ling, over to you.
  • 02:28<v Dr. Liu>Thank you Matt and thank you William,</v>
  • 02:30and also Donna for having me today,
  • 02:34have this opportunity to present
  • 02:38the qualitative comparative analysis,
  • 02:42relative new methodology to public health.
  • 02:46And I consider this opportunity
  • 02:48as a way to discuss with our scholars
  • 02:57and also broader the community,
  • 03:00to explore the utility of this method
  • 03:02in public health, in intervention, evaluative science.
  • 03:10And I am not expecting to use this opportunity
  • 03:14as an education of this method,
  • 03:19like within this 30 or 40 minutes.
  • 03:26And so today, I am going to introduce
  • 03:30this new method to you and also discuss about the literature
  • 03:36and the discussion of the utility of QCA methodology
  • 03:40in implementation sense.
  • 03:41And lastly, I will use empirical study from my work,
  • 03:48set as an example to show a little bit
  • 03:51about my experienced business method.
  • 03:55So what is QCA?
  • 03:59So in one short sentence, it uses Boolean logic
  • 04:03to identify all possible combinations
  • 04:06of variables, conditions.
  • 04:09It's a QCA terminology that influences the outcome,
  • 04:13and also as scholars and we are very curious
  • 04:17about the receptiveness of this matter
  • 04:20and what are the publication opportunities
  • 04:23of using this method.
  • 04:25And the good news,
  • 04:26that it welcomes for growing opportunities on conferences
  • 04:31and also the publications in journals
  • 04:35that have been majorly published in business,
  • 04:39management, political science,
  • 04:42and also is emerging in public health
  • 04:45and health services research journals.
  • 04:47But we also acknowledge the challenges exist,
  • 04:52that's mostly in how to visualize
  • 04:56the findings from the QCA and how to interpret
  • 04:59and how to communicate this non-QCA experts
  • 05:05in our scholarship.
  • 05:11And here, I cite a figure from the latest math book
  • 05:18from Melloo and he is based in Europe
  • 05:24and so his book has summarized
  • 05:29the recent journal articles published on QCA
  • 05:33and you can see that public health is emerging,
  • 05:37but it is still relatively new.
  • 05:42And here, I would like to summarize three main features
  • 05:48of the QC methodology
  • 05:50and I first consider it is a mixed method
  • 05:54that bridges the qualitative and quantitative analysis.
  • 05:58So it's a non-additive and nonlinear method
  • 06:02that is to identify all the combinations
  • 06:04of necessary and sufficient conditions,
  • 06:08the factors for an outcome.
  • 06:11And so for using QCA, it requires the researchers
  • 06:17to have the familiarity of these cases
  • 06:20to have the in-depth knowledge of your cases,
  • 06:25but also it's enables the researchers
  • 06:28to examine the cross-case patterns.
  • 06:31So it acknowledges the diversity and also heterogeneity
  • 06:37of the research study,
  • 06:39with regard that it allows the researchers to identify
  • 06:44what are the different solutions
  • 06:47of different combinations of the conditions
  • 06:51for the occurrence of the outcome of your interest.
  • 06:55And second feature, I think is important to understand QCA
  • 07:00is to assess the sufficient and necessary conditions
  • 07:05for the success or failure of the outcome.
  • 07:08So it's very different
  • 07:09from our conventional statistic influence techniques.
  • 07:15And by looking at the sufficient and necessary conditions
  • 07:21for the success or failure of the outcomes,
  • 07:23it provides researchers or the practitioners the approach
  • 07:31to identify more than one solution
  • 07:33or we call recipe to an outcome.
  • 07:38And also the presence or the absence of these factors
  • 07:42in relation to the other conditions might be key.
  • 07:46And also in QCA study
  • 07:49and the specific factors explain the success
  • 07:53does not imply that their absence would lead to the failure.
  • 07:57And the third feature, I think is important,
  • 08:02is that QCA is ideal, given the nature of this
  • 08:06and the underlying logic of this matter.
  • 08:09It's very ideal
  • 08:11for the small to intermediate sample size research design.
  • 08:16And because it's within this range, like 10 to 15 cases,
  • 08:21there are often too many cases
  • 08:24for researchers to keep all the knowledge
  • 08:26about all the cases,
  • 08:28but too few cases
  • 08:30for most conventional statistical techniques.
  • 08:34And here I share a few important methodology references,
  • 08:40which may be helpful
  • 08:41if some of you are interested to read and explore more.
  • 08:47And so come to our interest,
  • 08:51what is the utility of this method
  • 08:54in implementation science?
  • 08:56And I found two literature
  • 08:58which I found they are very useful for me to understand
  • 09:03what has been done in this area.
  • 09:06And so one is the systematic review by Hanckel
  • 09:10and which is just published is out at BMC Public Health
  • 09:14and the other report paper
  • 09:19and it has been using, apply the QCA
  • 09:23to identify the features of the strategies
  • 09:28related to mental health care
  • 09:30for children and adolescents by the RTI
  • 09:34and it has been published as agency for healthcare
  • 09:39and quality research publication series.
  • 09:43So I think those two are very useful
  • 09:46if you want to read more.
  • 09:50So here, just to summarize,
  • 09:53and in existing literature
  • 09:57so the selection criteria have been used
  • 10:01as published in English and up to December 2019
  • 10:05and there are a total of 27 papers used QCA
  • 10:11in evaluating the public health interventions.
  • 10:15And here are a few domains I list out,
  • 10:20like nutrition, obesity, health equality,
  • 10:24community engagement and also chronic condition management.
  • 10:29And so here, I want to show you
  • 10:32the sample research questions
  • 10:34or rationale for using the QCA
  • 10:37that you may be interested to consider
  • 10:41whether QCA's potential approach for you to use
  • 10:45in your research or analyzing your data.
  • 10:47So the simple research questions,
  • 10:50you can see that QCA also answers questions,
  • 10:54"What combinations of the components
  • 10:57might serve as recipes for success."
  • 10:59Of the outcome or if you are interested to identify
  • 11:04the critical features or characteristics
  • 11:07of the implementation program
  • 11:10that leads to the successful implementation outcomes
  • 11:15or if you are interested to identify
  • 11:19what are the necessary or sufficient conditions or factors
  • 11:24that are key to the implementation
  • 11:28of this public health intervention.
  • 11:31And also I want to say the QCA is mostly used
  • 11:39in the description or explanation studies.
  • 11:43So in the description studies,
  • 11:46it's very straightforward QCA,
  • 11:49you can use QCA to summarize the patterns
  • 11:52across your cases
  • 11:56or used in explanation studies that help you test
  • 12:02your existing hypothesis and choose to test out
  • 12:07whether your empirical cases can be reflected
  • 12:10by some or any combinations of the factors
  • 12:16from this existing theory.
  • 12:19And here is the QCA research cycle.
  • 12:23So it starts to pose the research problem
  • 12:29and ask the research question
  • 12:31and to figure out the scope of your research question
  • 12:35and then use the existing theories
  • 12:40or like the empirical evidence,
  • 12:44to consider to select which cases into your study
  • 12:51and then you will need to select the conditions,
  • 12:54like conditions are the factors,
  • 12:56you can under consider those are the factors
  • 13:00and then the key steps are to calibrate the data
  • 13:06and to conduct the analysis
  • 13:14to identify the necessary conditions
  • 13:17and also the sufficient conditions.
  • 13:20And the full process is an iterative process
  • 13:25that you will need to come forth and back
  • 13:29and to adjust with the scope of your research question
  • 13:36and also the selection of cases and the thresholds
  • 13:42and the decision rules for calibrating your data sets.
  • 13:49And so the strengths and weakness
  • 13:51of the QCA implementation science has been discussed
  • 13:57in a way that it provides a systematic approach
  • 14:01for understanding the mechanisms that work
  • 14:03in implementation across the context.
  • 14:07And the weakness however have been reported
  • 14:09related to the data availability limitation,
  • 14:12especially on ineffective interventions
  • 14:17And the software packages are evolving,
  • 14:23still in development,
  • 14:24but a few packages are major and ready for use
  • 14:30and you can go to this website for a full list,
  • 14:35but for the major softwares have been developed
  • 14:39as the FSQCA, QCA software
  • 14:43and also there are a few packages developed
  • 14:46on our environment that are for use.
  • 14:51And here I want to just show a few examples
  • 14:55of visualizing the QCA findings.
  • 14:58And so, in the existing literature
  • 15:02I found that the Venn diagram and also the chart table
  • 15:06have been mostly used and again it's evolving
  • 15:12and so scholars and researchers are still exploring
  • 15:18what are the most efficient ways to communicate
  • 15:24with our audience about the findings from the QCA study.
  • 15:30So here I want to use one example study from my work
  • 15:38that I collaborated with my colleagues
  • 15:43and we use data from primary care practices
  • 15:46to explore the system features of primary care practice
  • 15:50that promotes better provider experience.
  • 15:53And this work had been variously published
  • 15:57at Academy of Management
  • 15:59and also Healthcare Management Review.
  • 16:05So in this study
  • 16:08we focus on the providers in primary care practices
  • 16:12and we know that the primary care providers also experience
  • 16:16low rates of clinical work satisfaction
  • 16:19and high rates of burnout
  • 16:21and the poor satisfaction may adversely affect the quality
  • 16:26of care they deliver to their patients
  • 16:29and adversely related to patient outcomes
  • 16:33and patient experience.
  • 16:35And what have been not exams or studies much
  • 16:41is what are the system level features
  • 16:45affecting the provider's satisfaction
  • 16:47in their clinical work practice?
  • 16:51So in this study we asked a research question,
  • 16:55"Which system features and in what combinations
  • 16:58of this features can help to improve primary care provider's
  • 17:03clinical work satisfaction?"
  • 17:06And this study was conducted in collaboration
  • 17:11with 19 Harvard affiliate primary care practices
  • 17:15and we surveyed a total of 19 managers
  • 17:19and a total of 854 primary care providers
  • 17:25completed the survey.
  • 17:27And for the managers of the survey and interview,
  • 17:31one manager of each of these 19 primary care practice.
  • 17:38Our hypothesis is to look
  • 17:43at our automated outcome of increase, the system outcome,
  • 17:47providers clinical work satisfaction,
  • 17:51and this outcome is positively related,
  • 17:56as the system features of primary care practices
  • 18:00that include the team dynamics
  • 18:03and provider perceptions of safety culture
  • 18:06and also the care coordination among the providers
  • 18:10to their patient care.
  • 18:13And further, the hypothesis is that the enabling functions
  • 18:20of these primary care practices,
  • 18:22including operational functions,
  • 18:25that goes into eight domains,
  • 18:27and also the health information technology HIT functions
  • 18:33are positively related with each of our system features,
  • 18:39the overall team dynamics,
  • 18:42the provider perceptions of safety culture
  • 18:45and also the care coordination among providers.
  • 18:50And within the operational care process functionality
  • 18:54of the practices, we categorize into eight domains.
  • 18:59So including appointment and referral system
  • 19:03for high risk patients and also for routine patients,
  • 19:07abnormal test result management,
  • 19:10cancer screening for high risk patients
  • 19:12and also for routine patients,
  • 19:14patient center care, patient safety
  • 19:17and care transitions across the primary care practice
  • 19:22and emergency departments or the hospitals
  • 19:25or the other specialist departments
  • 19:29and the data, so we use the self-assessment service
  • 19:34for primary care providers variables,
  • 19:40including the clinical work satisfaction and team dynamics,
  • 19:45provider perceptions of safety culture and care coordination
  • 19:49among the providers towards patient care.
  • 19:52And for enabling functions,
  • 19:55they surveyed and interviewed the managers of the practice
  • 20:00on a total of eight domains
  • 20:02of the operational care process functions
  • 20:05and also 42 items of HIT functions.
  • 20:10And so, the method is we use the QCA
  • 20:14and again it's based on Boolean logic.
  • 20:17Here are just a few examples of the logic
  • 20:22and logic or, or negation knots
  • 20:25that is used in Boolean logic.
  • 20:28And so, we use QCA to compare the cases
  • 20:32to identify the combinations
  • 20:34of necessary and sufficient conditions,
  • 20:37the variables that trigger the outcome.
  • 20:41And in QCA the key step is to construct the Truth Table.
  • 20:47And here is an example from one hypothesis,
  • 20:50of testing one hypothesis in our study.
  • 20:55And so you can see that this is a table
  • 20:58that includes eight rows
  • 21:00and so the table is a two case power table
  • 21:05and we have three explanatory variables here
  • 21:08and one outcome.
  • 21:09So we have a total of eight rows
  • 21:12and each row we can consider as a recipe
  • 21:15that's a combination of the logically possible conditions.
  • 21:21And the one indicates the presence
  • 21:24of this factor in this recipe
  • 21:28and the zero indicates the absence of this factor
  • 21:32in this recipe.
  • 21:35Then the other main methodology
  • 21:39is to use the Quine-McCluskey algorithm
  • 21:44to reduce the roles of the Truth Tables to bring equations
  • 21:50and to minimize the combinations
  • 21:52which yields the prime recipes.
  • 21:56And QCA uses two goodness-of-fit statistics
  • 22:00and what is consistency?
  • 22:03So it's range from zero to one
  • 22:07and it indicates the strength of association
  • 22:10between the conditions and outcome
  • 22:13and the coverage also ranges from zero to one
  • 22:17and it indicates the proportion of the cases
  • 22:22that are covered in a specific recipe.
  • 22:24So here in our study,
  • 22:26it indicates the proportion of the practice sites
  • 22:30that have a specific bundle.
  • 22:33Here is a example of the consistency and coverage scores
  • 22:38from testing this hypothesis in our study.
  • 22:43And here I want to talk again
  • 22:49about a few main features of QCA method.
  • 22:54So it identifies the combinations of the conditions,
  • 22:57capable of yielding the same outcome
  • 23:01and therefore it can be multiple pathways
  • 23:05and the outcome and non-outcome
  • 23:07may require different explanations.
  • 23:09So it is important that you define the outcome
  • 23:13in your testing,
  • 23:15for example in the example which I just presented,
  • 23:19is the outcome we define as grade level satisfaction
  • 23:25among the primary care providers.
  • 23:30So the non-outcome is the lower level satisfaction
  • 23:35among the primary care providers
  • 23:37and so it requests the researchers to test the separate sets
  • 23:43of the combinations of the factors,
  • 23:45leads to the outcome or the non-outcome.
  • 23:49So it contrasts with the next effects thinking
  • 23:54that usually have been applied
  • 23:56in conventional statistical techniques.
  • 24:00And in this study using the QCA,
  • 24:03the rationale for choosing QCA is that it enable us
  • 24:07to identify the system level characteristics
  • 24:10that influence the provider experience.
  • 24:16And the findings, so the first task,
  • 24:21the contribution of each system features
  • 24:25to our system outcomes.
  • 24:28The team dynamics provide a perception
  • 24:31of safety culture and peer coordination among providers.
  • 24:34Each of those three system features
  • 24:38with the outcome of increase,
  • 24:40the raised clinical work satisfaction
  • 24:43and we can see
  • 24:44that it's yields very high consistency and modus coverage.
  • 24:50And then we test the bundles of these system features,
  • 24:56like team dynamics and provider perceptions
  • 24:59of safety culture together,
  • 25:02you can see it yield very high consistency
  • 25:05and also high coverage
  • 25:08and also the provider perceptions of safety culture
  • 25:12and peer coordination among providers,
  • 25:15you can see the consistency remains very high
  • 25:18but the coverage drops
  • 25:21and also we test all of them together
  • 25:24like the set relations of the three system features
  • 25:28based the outcome.
  • 25:30And you can also see that the consistency remains high,
  • 25:34but the coverage is relatively low, it's only 0.32.
  • 25:41And so, we are expanding the analysis
  • 25:47to include our enabling functions
  • 25:50of the primary care practices
  • 25:53and in our argument, in our final results
  • 25:57and we identify there are three key components
  • 26:02of the operational care process functions.
  • 26:07One is the number three, abnormal test result management
  • 26:11and the number five,
  • 26:13cancel screening for high risk patients.
  • 26:16And number eight is the care transitions
  • 26:19across the primary care practice
  • 26:22and emergency departments or hospitals
  • 26:26and plus this HIT functions,
  • 26:30that they together are the core factors
  • 26:36consisting of the solutions which would yield to the outcome
  • 26:41of our interest, like the strong team dynamics
  • 26:47and also greater level provider perceptions
  • 26:52of safety culture.
  • 26:58So to interpret what we have found in the QCA analysis.
  • 27:08So, "Favorable team dynamics
  • 27:10combined with a strong safety culture contribute most
  • 27:14to the greater clinical work satisfaction."
  • 27:18And, "Provider-perceived safety culture
  • 27:21acts as a core sufficient condition
  • 27:23that presents in both recipes,
  • 27:26yielding for PCP's great clinical work satisfaction."
  • 27:30And, "For the most empirical appliances,"
  • 27:34that means from our empirical cases,
  • 27:38"A strong safety culture is not sufficient on its own
  • 27:44and practice also needs to to create and also implement
  • 27:52the highly functioning teams."
  • 27:54Like to encourage them to foster the strong team dynamics,
  • 28:00visiting the primary care practices.
  • 28:04And also our findings indicate the, "HIT functionality alone
  • 28:10is not sufficient to achieve the desired outcomes."
  • 28:15This is occurring a lot
  • 28:16with what we know from the literature,
  • 28:20because a lot of literature found
  • 28:23that HIT generates a few benefits,
  • 28:27but also to overly emphasize on the utility of HIT
  • 28:34may bring a few adverse effects,
  • 28:37like to increase the volume of the workloads to providers
  • 28:44and contribute to their burnout issues.
  • 28:48So from our analysis, QCA analysis,
  • 28:52it identifies that the HIT functionality
  • 28:56is a core component, but alone, it's not sufficient
  • 29:00to help our providers
  • 29:02to improve their clinical satisfaction.
  • 29:05And also look
  • 29:06at the operational care process functionalities
  • 29:09and we found that the common features of the three factors
  • 29:16which we identify,
  • 29:18they represent it's importance to enable the functions,
  • 29:24identify urgent or complex acute illness
  • 29:29and also request the collaborations
  • 29:32across institutional settings.
  • 29:35And this served as the key factors
  • 29:38within the operational care process functionalities
  • 29:42that can enable our providers
  • 29:45to achieve better team dynamics
  • 29:47and also their perception of safety culture.
  • 29:54And now I want to discuss
  • 30:00a little bit more about the practice implications
  • 30:03of using the QCA in our study.
  • 30:06I see the most attractive part of using QCA
  • 30:12is that it helps to generate the message
  • 30:15that can be very useful and practical for our managers
  • 30:22or the practitioners, in-house systems, for them to use
  • 30:27because usually they are more interested
  • 30:31what are the solution pathways
  • 30:34that we can implement in our systems,
  • 30:37rather than increase on the net effects
  • 30:41of each individual factors, effect on the outcome.
  • 30:46So using QCA, it presents the multiple solution pathways
  • 30:55for our practitioners,
  • 30:59what are the most key factors you can focus
  • 31:03and, or prioritize, in order to achieve the outcome
  • 31:10of your implementation outcome or outcome interest.
  • 31:15So in our study,
  • 31:17because the real obstacles in primary care practices
  • 31:22is usually not possible to enable
  • 31:25or to invest the resource to improve all the conditions
  • 31:30or all the factors in our primary care delivery system.
  • 31:35And so to identify the bundles
  • 31:39can be the prioritized targets for our managers
  • 31:43to emphasize if they want to improve
  • 31:48their provider's work satisfaction.
  • 31:51And our study also highlights the human-centric nature
  • 31:55of the physician clinical work satisfaction,
  • 31:58like how HIT is important as a core components,
  • 32:03but it has to work, function,
  • 32:07with the other key factors together
  • 32:11and it informs the need for non-regulatory strategies.
  • 32:17And we also acknowledge there are a few limitations.
  • 32:21So by using QCA, we're not able to generate
  • 32:25the causal claims.
  • 32:26And also in QCA, one approach,
  • 32:30like to calibrate the data
  • 32:31actually is to refer to the existing empirical evidence,
  • 32:38but because the QCA is relatively new for public health,
  • 32:42evaluative science or health services research,
  • 32:47so external standards or empirical evidence that published
  • 32:53for data calibration are not yet available or established.
  • 33:02And also QCA method may be prone to the type one errors.
  • 33:07And I want to stop at here
  • 33:10and also welcome for a few questions
  • 33:13and if you have data sets
  • 33:16that you think may consider QCA as an approach
  • 33:22to analyze your data to answer the research question,
  • 33:28what QCA can help to work best.
  • 33:34And so welcome to Rachel and I'm very passionate
  • 33:41on exploring computer exploration of this method
  • 33:45in implementation science studies.
  • 33:48Thank you very much.
  • 34:01Any questions?
  • 34:05<v Donna>Yeah, hi Lingrui, this is Donna.</v>
  • 34:08<v Dr. Liu>Hi Donna.</v>
  • 34:08<v Donna>Hi, thank you for the excellent and clear talk.</v>
  • 34:11I really appreciate it.
  • 34:13I have a couple of questions.
  • 34:14So this one is sort of a point of information.
  • 34:17I came in a little late unfortunately
  • 34:19and I didn't catch those two measures.
  • 34:22What is consistency?
  • 34:23And there was something else,
  • 34:25another measure that was appearing
  • 34:27on a number of your slides?
  • 34:29<v Dr. Liu>Yeah, so one is consistency</v>
  • 34:32and one is coverage.
  • 34:33So consistency indicates the strength,
  • 34:36you can consider as the p value,
  • 34:42it's very like the p value in regressions
  • 34:47and it indicates the strengths of the association-
  • 34:52<v Donna>I'm sorry, the strength of the association</v>
  • 34:55of what with what?
  • 34:56<v Dr. Liu>Of explanatory.</v>
  • 34:58I'm trying to not use the terminology from our regression
  • 35:06or statistics to explain the QCA,
  • 35:09because they are definitely two different methods.
  • 35:14But because of my experience of presenting this method,
  • 35:19I know that usually it's helpful
  • 35:21to borrow some terminology
  • 35:24from the conventional statistic analysis
  • 35:28to interpret the terminology in QCA.
  • 35:33And so back to your question,
  • 35:39so consistency indicates the strength of the relationship
  • 35:44between the explanatory variables and the outcome.
  • 35:49So actually in QCA,
  • 35:50because it's based in Boolean logic,
  • 35:53it's actually not, variables is the conditions.
  • 35:57So it's identifying
  • 35:59what are the necessary and sufficient conditions
  • 36:03that would lead to the occurrence of the outcome.
  • 36:08And the other measure is the coverage,
  • 36:15it also ranges from zero to one.
  • 36:18It tells the proportion of, for example, in my studies,
  • 36:23the proportion of the practice sites
  • 36:26which have the specific bundle,
  • 36:30so it tells the empirical appliance.
  • 36:34Because in QCA, you first identify given your conditions
  • 36:39and also the case data, you could identify
  • 36:44what are all the logically possible solutions,
  • 36:48but logically possible solutions are not all applied
  • 36:53in your empirical cases.
  • 36:56So coverage tells within your empirical cases,
  • 37:01what the proportion of your cases have a specific bundle
  • 37:08or a specific solution, I hope it helps!
  • 37:14<v Donna>Sort of, well I had a couple of other questions,</v>
  • 37:17but let's see if other people have questions first.
  • 37:32<v Luke>Thanks for the great talk.</v>
  • 37:34I have a question about the early part
  • 37:36of the thematic analysis part.
  • 37:38Is that different in qualitative comparative analysis
  • 37:40than it would be,
  • 37:41maybe with other more traditional techniques
  • 37:43or does it sort of operate similarly?
  • 37:45Obviously you're applying these codes
  • 37:49to what you're learning from the sites.
  • 37:55<v Dr. Liu>Sorry, I missed the first part of your question.</v>
  • 38:01<v Luke>I'm asking a little bit</v>
  • 38:02about how you code these themes
  • 38:05from the data that you're getting from the participants,
  • 38:08is that different than you do
  • 38:09in traditional qualitative, say, thematic analysis
  • 38:12or does it operate according to similar rules?
  • 38:17<v Dr. Liu>This is a great question.</v>
  • 38:20Yeah, actually this touches up on the key part
  • 38:24of the QCA analysis.
  • 38:30Given my experience working with this method,
  • 38:33I consider, it's kind of a build up
  • 38:38on the conventional qualitative or quantitative analysis,
  • 38:44that you have a few cases
  • 38:48and then you will apply the conventional qualitative coding
  • 38:54to your data, for example you have interview data
  • 38:59and also then the additional steps,
  • 39:03you need to calibrate your data to re-skill your data
  • 39:11into membership range,
  • 39:15just the two in very simple words is from zero to one,
  • 39:19like rescale your data into zero to one.
  • 39:24And there are two approaches in QCA,
  • 39:27one is crisp QCA and one's fuzzy sets QCA.
  • 39:33So basically you set up, you need to discuss this,
  • 39:38the empirical experts
  • 39:40and also who has the knowledge about the cases
  • 39:45to decide what are the thresholds to be used
  • 39:50to rescale your data sets,
  • 39:53like the codes used to calibrate your data sets
  • 39:59into the range of zero to one.
  • 40:03So for example, you have to define
  • 40:08what are the three thresholds you need to use,
  • 40:14to calibrate the outcome of grades level satisfaction
  • 40:21among primary care providers.
  • 40:24So these surveys,
  • 40:27the original survey uses zero to five scores,
  • 40:31but in QCA there are a few decision rules
  • 40:39like consider the statistical characteristic of your data
  • 40:44and also refer to the existing empirical evidence
  • 40:51and also your knowledge,
  • 40:54the researcher's knowledge about your data, your cases.
  • 40:59And together you decide what are the decision rules
  • 41:03to set up the thresholds to rescale the data sets,
  • 41:10rescale the data on the outcome variable
  • 41:14into the zero to one.
  • 41:16So for each of your variable
  • 41:18you have the same principles of decision rules,
  • 41:28which would lead to yields into different thresholds,
  • 41:34for each of variables to be rescaled into that range,
  • 41:39like zero to one range.
  • 41:45Is that helpful?
  • 41:47<v Mona>I had a question,</v>
  • 41:48somewhat related to what Luke asked
  • 41:50and maybe my question will also kind of get into more depth
  • 41:53around this issue.
  • 41:53So it sounded like what you were just describing
  • 41:55was the process of defining your outcome
  • 41:58of sort of clinician satisfaction
  • 42:01and defining how you're gonna take something
  • 42:04that's more continuous score or continuous measure
  • 42:07into a binary outcome
  • 42:09where you could do something like QCA,
  • 42:11on the other side of the predictors or the factors
  • 42:15that you are associating with satisfaction,
  • 42:18it sounds like in this study you were using a survey,
  • 42:21potentially with some validated measures
  • 42:23of certain factors.
  • 42:25Related to Luke's question,
  • 42:26I feel like I've seen some presentations of QCA
  • 42:29where they've used qualitative interviews or focus groups
  • 42:33and they've sort of coded,
  • 42:36using standard qualitative methods,
  • 42:38coded the outcomes or the factors
  • 42:43and then kind of used that group consensus
  • 42:46to sort of translate that coding into quantitative,
  • 42:49I wondered if you could talk to us more about that,
  • 42:51'cause I feel like QCA
  • 42:53to me has a lot of potential in mixed methods approaches
  • 42:56as a way to formalize that hypothesis generation process
  • 43:01that you so nicely kind of displayed here.
  • 43:04So I'd love to have you talk a little bit more
  • 43:06about the different applications of QCA in surveys
  • 43:09versus more pure qualitative interviews
  • 43:12and open-ended responses.
  • 43:14<v Dr. Liu>Yeah, and this is a great question.</v>
  • 43:17So from my understanding of this matter,
  • 43:21I consider this is a mixed matter
  • 43:24and yeah it is true that it can be case oriented QCA
  • 43:32or variable oriented QCA,
  • 43:34but I understand in a way, that's the nature of the case
  • 43:39or variable is the same thing.
  • 43:45I mean, ideally you can design the data collection after,
  • 43:51as I show like in the reference,
  • 43:57like the research starts phase,
  • 43:59you have the research problem,
  • 44:00you have approximate research question you want to explore
  • 44:06and you refer to the existing theory
  • 44:09to guide you post the hypothesis
  • 44:13and to guide your data collection,
  • 44:17to help with your data design.
  • 44:20And you apply the QCA to analyze these data sets.
  • 44:26But in practice, like for example in our study,
  • 44:30and we first have the service completed in the whole program
  • 44:39and then we figure out our research question,
  • 44:44it's more interesting at the system level,
  • 44:47at the primary care practice level.
  • 44:50And we were very curious
  • 44:53to explore how QCA can help us to answer this question.
  • 44:59So we have our data already completed
  • 45:05and the compliments with the interviews,
  • 45:07like the small size interview,
  • 45:11the qualitative interview for the manager
  • 45:15of each primary care practices,
  • 45:18but ideally, if you can apply the QCA,
  • 45:26consider to use this method
  • 45:28at the stage of asking your research question
  • 45:31and write your proposal and to combine the implements,
  • 45:42the way how to design your data collection,
  • 45:48either the service or qualitative interviews
  • 45:52in your data collection,
  • 45:55in the way that the QCA would need,
  • 45:58like the qualitative data or quantitative data.
  • 46:04So that's one limitation of our study
  • 46:09that we were not able to confirm that we want to use the QCA
  • 46:17and then we use the QCA framework
  • 46:21to guide our data collection.
  • 46:23And so now I have a project
  • 46:27that I work with my here and Donna
  • 46:32and also our colleagues in China
  • 46:34that we now already proposed the research questions
  • 46:38as the hospital level or like the organizational level
  • 46:43and we will use the QCA frameworks
  • 46:47to help guide our data collection.
  • 46:50So that will solve a few issues that may come out
  • 46:56as the limitations of the study.
  • 46:59And also another thought related to your question
  • 47:03about using qualitative and quantitative data
  • 47:07in the QCA analysis,
  • 47:12so in my study, the majority of my data is the survey data.
  • 47:18But from my study of this method,
  • 47:21is that for working with QCA in the qualitative data
  • 47:28is that after using the traditional qualitative coding
  • 47:34you will needs to take additional steps,
  • 47:39to calibrate the data into scale of zero to one
  • 47:44to indicate the extent to which of your variable,
  • 47:51from the lower membership to higher membership,
  • 47:56you can understand the way the lower performance
  • 47:58of this variable to the higher performance
  • 48:01of this variable in this study.
  • 48:07Yeah, did I answer your question?
  • 48:11<v Mona>I think so.</v>
  • 48:12Somehow getting group consensus, in terms of quantifying,
  • 48:19almost like labeling of a variable.
  • 48:21So for example, I'm really thinking about
  • 48:24how much this might be of relevance to Leslie,
  • 48:27the work you've done in positive deviant studies,
  • 48:29sort of identifying sites or organizations
  • 48:33that are really excelling,
  • 48:34or individuals that are really excelling
  • 48:36and the sites that maybe are not.
  • 48:38And then using QCA to sort of label
  • 48:41some of the factors that might be potential drivers.
  • 48:44And I think Ling what I'm hearing you say
  • 48:46is that you would have to assign some numerical scale
  • 48:50to those factors, in terms of their presence or absence
  • 48:55and then maybe ranges along that scale.
  • 48:59<v Dr. Liu>Yeah, yeah.</v>
  • 49:01<v Donna>Yeah, I am still mystified by this</v>
  • 49:03and I've heard Ling talk about it,
  • 49:05maybe a half a dozen times.
  • 49:06I really wanna learn and understand, I really do
  • 49:10and, you know, each time I get a little closer,
  • 49:12but in this instance,
  • 49:13the calibration to me feels really daunting.
  • 49:17Like as the analog and a qualitative data set,
  • 49:20if we imagine, those of us,
  • 49:21there's a bunch on the panel here who do qualitative work.
  • 49:24You know, if you're in a large group of coders,
  • 49:28getting consensus on a construct can be really hard.
  • 49:31Just even what is this thing?
  • 49:34And so then to have to parse that even further
  • 49:38to say like, yes, no, it exists.
  • 49:42If you're imagining, I don't know, some intangible quality,
  • 49:46if in our work, if we're looking at organizations
  • 49:48and the way they behave and dimension of culture.
  • 49:52So I think how this might work in these small case studies,
  • 49:56these positive deviant studies
  • 49:58where you may have 10 or 12 organizations
  • 50:00or units of analysis,
  • 50:02would be having to move
  • 50:04from not only consensus around coding,
  • 50:07so how do you interpret
  • 50:08a particular piece of qualitative data,
  • 50:11but then this fuzzy piece, like where's the boundary?
  • 50:16Is it a yes or no?
  • 50:17Is it a leadership engagement?
  • 50:21Is it there, yes or no?
  • 50:23So that to me feels daunting.
  • 50:25But if one could accomplish that
  • 50:27in the coding of the narrative textual data,
  • 50:31it seems like there's huge potential to look differently
  • 50:33at combinations of patterns,
  • 50:35which to me, continues to be the takeaway here,
  • 50:38trying to distill
  • 50:40through many, many, many combinations of variables,
  • 50:42if we look at organizational culture measures,
  • 50:45a hundred variables,
  • 50:47how do you find the right combination of the six
  • 50:51that are gonna get you the farthest,
  • 50:52if you're somebody who needs to intervene,
  • 50:55if you're trying to intervene organizationally.
  • 50:57But yeah, I'm on a learning curve, that's for sure.
  • 51:01But I could see Mona, how it might help
  • 51:02in those kinds of designs.
  • 51:05But there's a lot of work
  • 51:06on the qualitative interpretation side, I think.
  • 51:10<v Dr. Liu>Thank you for your insights and comments Mona.</v>
  • 51:15Yeah, at the beginning I said
  • 51:17this is not a educational workshop about the method
  • 51:21and I consider this a forum where we can discuss
  • 51:26and to explore further
  • 51:30as I present, display, methods relatively new
  • 51:35to probably health and evaluative science.
  • 51:40And so I consider this an opportunity,
  • 51:42I can introduce the method to our broader audience
  • 51:46and if you have more data set,
  • 51:48or you have a similar research question
  • 51:51that you think are similar to this
  • 51:54and you may consider to use the QCA
  • 51:58to help with your analysis.
  • 51:59And as you see the years, like they're pretty new,
  • 52:02like recent, three or four years
  • 52:07and also have been most conducted
  • 52:09in high income country settings.
  • 52:12So I see there is a huge room
  • 52:16for implementation science scholars
  • 52:19and practitioners to explore.
  • 52:25And I'm also on the learning curve!
  • 52:27(Dr. Liu Laughing)
  • 52:28And back to one point, lastly mentioned
  • 52:32about how to select the case
  • 52:35and also select the variables,
  • 52:37from my experience and the study of the method
  • 52:40is like, now I think it's important
  • 52:44you have the hypothesis from existing theory,
  • 52:51to guide you.
  • 52:52So it's not possible to include all the factors
  • 52:56of relevance in your analysis,
  • 53:05like one key step is you use the calibrated data
  • 53:10to construct the Truth Table, the two two case power table.
  • 53:15So for example, you have three conditions
  • 53:19or three explanatory variables,
  • 53:21you will have eight rows.
  • 53:23Think about this way,
  • 53:24you have eight explanatory variables,
  • 53:27you will have over 200 rows,
  • 53:31it's eight multiplied by eight.
  • 53:38So you have to limit, what are the key variables
  • 53:45extracting from existing empirical knowledge
  • 53:50or the theory to guide you,
  • 53:54select the case and also variables.
  • 53:56And I think it's important to also keep in mind the outcome.
  • 54:08I think yeah, definition of your variables
  • 54:11and also calibrating your data are very important,
  • 54:17because I consider it's a way to help you to summarize
  • 54:23or describe the patterns of the relations
  • 54:28between your condition variables
  • 54:31and your outcome variable, yeah.
  • 54:34(Dr. Liu Laughing)
  • 54:35<v Donna>So Ling let me ask</v>
  • 54:36what might be the last question
  • 54:38or it shouldn't even be asked,
  • 54:40'cause people probably have to wrap up and go.
  • 54:42But to me, like the two to the K table
  • 54:46that's I don't wanna say just,
  • 54:48but that seems to be very similar if not identical
  • 54:51to what happens in a full factorial design.
  • 54:55And then once you have the factorial design
  • 54:58and you have all the factors,
  • 55:00there are different approaches to kind of using regression
  • 55:03and variable selection, even machine learning
  • 55:06to try to pick what main effects there might be
  • 55:10and combinations and whole packages and so forth.
  • 55:14That might be the most effective with respect to an outcome.
  • 55:18So I'm not sure how this is different from that,
  • 55:21once you get to the quantitative side,
  • 55:23there probably isn't time to say
  • 55:25and maybe we just need to look more carefully
  • 55:27and maybe it is very similar
  • 55:29and people get to similar spots
  • 55:34from different starting points.
  • 55:37But I'm wondering if this analysis is done
  • 55:40after an intervention is conducted
  • 55:43or is this observational research
  • 55:45to try to develop the intervention
  • 55:48and figure out which two to the K combinations
  • 55:51are the best ones to test now in a randomized trial?
  • 55:55'Cause all of this is also very close
  • 55:57to the MOST design of Linda Collins.
  • 56:01But I don't know, maybe it's just some comments
  • 56:04or food for thought
  • 56:05and we probably should let people go
  • 56:07and maybe Ling, we can talk about it some other time?
  • 56:10<v Dr. Liu>Yeah, and I just agree with your comment.</v>
  • 56:14I'd say now the QCA scholarship,
  • 56:17they are discussing about applying this method
  • 56:20to longitudinal, like large sample sets
  • 56:23and also combine with the techniques
  • 56:30from the conventional statistics,
  • 56:32like the machine learning, like that's what you mentioned.
  • 56:35But that is like too new.
  • 56:38I think that probably, at this point,
  • 56:44probably we want to start from the beginning
  • 56:47to understand this method
  • 56:48and also encourage some exploration
  • 56:51of the utility of this matter
  • 56:54in our implementation science projects.
  • 56:58But yeah, a lot of insights
  • 57:02and comments are very helpful today
  • 57:05from our audience, yeah, thank you.
  • 57:11I'm reading the message on charts.
  • 57:14(Dr. Liu Laughing)
  • 57:16<v Donna>Well, I don't know if mayor, maybe he has left,</v>
  • 57:20but I can as sort of a-co convener thank Ling
  • 57:23for this very interesting presentation
  • 57:26and thank everybody for participating.
  • 57:28And yeah, we'll look forward to further discussions
  • 57:31about this and looking at the relationship
  • 57:33between these different approaches in implementation science
  • 57:37to building complex multilevel interventions
  • 57:40that are effective and cost effective.
  • 57:43So thanks everyone and bye-bye.
  • 57:45<v Dr. Liu>Thank you, bye!</v>