Fangyong Li, MS, MPH
Statistician 3Cards
About
Research
Publications
2026
Anopheles Mosquitoes Exposed to Long-Acting Antimalarials via Drug-Supplemented Bloodmeal Absorb Drug but Do Not Suffer Fitness Costs
Goheen M, Orfanó A, Dah S, Foy B, Brackney D, Li F, Ouédraogo J, Da D, Dabiré R, Somé A, Bei A, Parikh S. Anopheles Mosquitoes Exposed to Long-Acting Antimalarials via Drug-Supplemented Bloodmeal Absorb Drug but Do Not Suffer Fitness Costs. Journal Of Infectious Diseases 2026, jiag300. PMID: 42296192, DOI: 10.1093/infdis/jiag300.Peer-Reviewed Original ResearchLong-acting antimalarialsAnopheles mosquitoesWorld Health Organization recommendationsPhysiological levelsDrug resistance spreadDrug exposureCmax concentrationsDose-dependentlyActive metaboliteImpact of drugsAbsorbable drugsAntimalarialsDrug impactWhole mosquitoesAbsorption extentEndemic areasOrganization recommendationsDrugDesethylamodiaquineTreatment useDrug distributionAmodiaquineMosquito feedingInfected mosquitoesParasite developmentRacial and ethnic differences in breast-conserving surgery after neoadjuvant chemotherapy for HER2-positive and triple-negative breast cancer.
Hickey A, Sun F, Li F, Proussaloglou E, Berger E, Greenup R, Valero M. Racial and ethnic differences in breast-conserving surgery after neoadjuvant chemotherapy for HER2-positive and triple-negative breast cancer. Journal Of Clinical Oncology 2026, 44: e13724-e13724. DOI: 10.1200/jco.2026.44.16_suppl.e13724.Peer-Reviewed Original ResearchTriple-negative breast cancerBreast-conserving surgeryNon-Hispanic white womenNeoadjuvant chemotherapyStage II diseaseHER2-positiveBreast cancerHigher oddsII diseaseSurgical managementClinical stageReceipt of breast-conserving surgeryStage II-III breast cancerComorbidity scoreRace/ ethnicityWhite womenHER2-positive diseaseNational Cancer DatabaseEthnic differencesYear of diagnosisPacific Islander womenLow comorbidity scoreAssociated with significantly higher oddsMultivariate logistic regressionSignificantly higher oddsDiagnostic yield of high-sensitivity cardiac troponin T for identifying obstructive coronary artery disease in patients with NSTE-ACS
Khokhar A, Sohal S, Ambrosini A, Li F, Sangal R, Possick S, Cigarroa N, Odanovic N, Kim N, Shah S. Diagnostic yield of high-sensitivity cardiac troponin T for identifying obstructive coronary artery disease in patients with NSTE-ACS. Cardiovascular Revascularization Medicine 2026 PMID: 42230218, DOI: 10.1016/j.carrev.2026.05.007.Peer-Reviewed Original ResearchObstructive coronary artery diseaseInvasive coronary angiographyCoronary artery diseaseHs-cTnT valuesHigh-sensitivity cardiac troponin THs-cTnT levelsHs-cTnTNSTE-ACSCardiac troponin TElevated hs-cTnTArtery diseaseDiagnostic yieldRetrospective analysisTroponin TRetrospective analysis of consecutive patientsNon-obstructive coronary artery diseaseAssociated with obstructive coronary artery diseaseIdentification of obstructive coronary artery diseaseAnalysis of consecutive patientsNon-ST-elevation acute coronary syndromeRisk factorsReceiver-operating characteristic (ROC) analysisHs-cTnT measurementsHs-cTnT testingHs-cTnT change724. A Summer of rTMS in a Residential Treatment Center Offers Support for a Potential Breakthrough in Treating Substance Use Disorders
Steele V, Carr J, Kang D, Charpentier J, Trujillo S, Li F, Stevens M, Alex E, Allen J. 724. A Summer of rTMS in a Residential Treatment Center Offers Support for a Potential Breakthrough in Treating Substance Use Disorders. Biological Psychiatry 2026, 99: s408-s409. DOI: 10.1016/j.biopsych.2026.03.958.Peer-Reviewed Original ResearchERBB2 activating mutations and co-occurring genomic alterations contribute to disease heterogeneity in patients with ERBB2-mutant lung cancer
Stockhammer P, El Zarif T, Schillo J, Li F, Goldberg S, Politi K, Grant M. ERBB2 activating mutations and co-occurring genomic alterations contribute to disease heterogeneity in patients with ERBB2-mutant lung cancer. Journal Of Thoracic Oncology 2026, 103708. PMID: 41932614, DOI: 10.1016/j.jtho.2026.103708.Peer-Reviewed Original ResearchFirst-line chemoimmunotherapyERBB2 mutationsTyrosine kinase domainNSCLC tumorsFH cohortCo-mutationsMedian tumor mutation burdenTyrosine kinase domain mutationsMultivariate Cox regression modelERBB2 activating mutationProgression-free survivalTumor mutational burdenExtracellular domainCharacteristics of patientsCox regression modelsFood and Drug AdministrationTrastuzumab deruxtecanMutational burdenMale patientsHigher RatesClinical outcomesSmoking historyActivating mutationsLung cancerGenomic alterationsHeterotopic Ossification After Multiligament Knee Injury Is Associated With Knee-Spanning External Fixation and Central Nervous System Trauma
Ayhan E, Levitt S, Nair M, Park N, Moran J, Katz L, Wang A, Li F, Song Z, Islam W, Medvecky M. Heterotopic Ossification After Multiligament Knee Injury Is Associated With Knee-Spanning External Fixation and Central Nervous System Trauma. Orthopaedic Journal Of Sports Medicine 2026, 14: 23259671261416523. PMID: 41727788, PMCID: PMC12921146, DOI: 10.1177/23259671261416523.Peer-Reviewed Original ResearchThis study investigates heterotopic ossification after multiligament knee injuries, showing a 35% incidence linked to external fixation and central nervous system trauma, guiding risk management strategies.Changes in cannabis use following legalization: Effects in first-episode psychosis
Purushothaman D, Tayfur S, Song Z, Li F, Corbera S, Sykes L, Riley S, Terashima J, D'Souza D, Tek C, Srihari V. Changes in cannabis use following legalization: Effects in first-episode psychosis. Schizophrenia Research 2026, 290: 86-87. PMID: 41671766, DOI: 10.1016/j.schres.2026.02.001.Commentaries, Editorials and LettersThis study investigates how cannabis legalization in Connecticut increased moderate-to-severe cannabis use among first-episode psychosis patients, raising concerns about potential health risks.
2025
Effect of a lifestyle intervention during chemotherapy for breast cancer on quality of life
Puklin L, Li F, Ferrucci L, Cartmel B, Harrigan M, McGowan C, Zupa M, Ligibel J, Sanft T, Irwin M. Effect of a lifestyle intervention during chemotherapy for breast cancer on quality of life. JNCI Cancer Spectrum 2025, 10: pkaf125. PMID: 41452765, PMCID: PMC12803784, DOI: 10.1093/jncics/pkaf125.Peer-Reviewed Original ResearchThis study investigates whether a yearlong nutrition and exercise program during chemotherapy improves quality of life in breast cancer patients, finding no significant benefits compared to usual care.Body mass index and chemotherapy completion among patients with newly diagnosed ovarian cancer
Cao A, Cartmel B, Ratner E, Li F, Schlumbrecht M, Kumar A, Crane T, Esserman D, Irwin M, Ferrucci L. Body mass index and chemotherapy completion among patients with newly diagnosed ovarian cancer. JNCI Cancer Spectrum 2025, 10: pkaf121. PMID: 41442446, PMCID: PMC12854082, DOI: 10.1093/jncics/pkaf121.Peer-Reviewed Original ResearchConceptsBody mass indexRelative dose intensityDose intensityOvarian cancerMass indexChemotherapy completionDose modificationRetrospective cohortRetrospective cohort of patientsContemporary treatment eraChemotherapy dose intensityHigher body surface areaHigher Body Mass IndexCohort of patientsBody surface areaBody composition dataAverage RDIDose cappingHigher RDIHematologic toxicityOvarian Cancer StudyAssociated with lower complianceDose reductionTreatment eraChemotherapyClinical profile and long-term outcomes of chest pain patients with coronary microvascular dysfunction from the emergency department – results from the Yale-CMD registry
Safdar B, Zhou B, Li F, Camici P, Dziura J, Jastreboff A, Lansky A, Shah S, Sinusas A, Spatz E, D'Onofrio G. Clinical profile and long-term outcomes of chest pain patients with coronary microvascular dysfunction from the emergency department – results from the Yale-CMD registry. Microvascular Research 2025, 163: 104878. PMID: 41110546, PMCID: PMC13092347, DOI: 10.1016/j.mvr.2025.104878.Peer-Reviewed Original ResearchConceptsCMD patientsCoronary microvascular dysfunctionLong-term prognosisLong-term outcomesCoronary artery diseaseCoronary flow reserveEmergency departmentMicrovascular dysfunctionProspective cohortHeart failureHealthcare utilizationMedian follow-up timeHigh riskCohort of ED patientsMyocardial infarctionCardiac positron emission tomographyHigher adverse eventsChest pain patientsFollow-up timeAdverse cardiac eventsHigher MACE riskHigher healthcare utilizationAnnual follow-upSeattle Angina QuestionnaireProspective cohort of ED patients
News
News
- February 15, 2026
After Legalization: More Severe and Concerning Cannabis Use in First-Episode Psychosis
- August 07, 2023
New Yale Study Shows Aerobic Exercise Relieves Pain for Ovarian Cancer Survivors
- August 03, 2023
Lung Adenocarcinomas: New Findings About Resistance to Targeted Therapies
- February 15, 2023
Discoveries & Impact (February 2023)
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