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Faculty and Staff

Peter Peduzzi, PhD

Peter Peduzzi PhD, Professor of Biostatistics in the School of Public Health is the Director of the DCC. He has more than 35 years of experience in designing, conducting and analyzing clinical trials. He is the former director of the VA Cooperative Studies Program Coordinating Center at West Haven Connecticut and the current director of the Yale Center for Analytical Sciences, which houses the Biostatistics Cores for the Yale CTSA and Cancer Center. He is also the former President of the Society of Clinical Trials and a fellow of the American Statistical Association, Society for Clinical Trials and Cardiovascular Epidemiology Section of the American Heart Association. He is a member of several FDA Advisory Committees, an NIH/NIA Clinical Trials Advisory Panel and several Data and Safety Monitoring Boards, for one of which he serves as the chair.

Jim Dziura, MPH, PhD

Jim Dziura is an Associate Professor in Emergency Medicine and Medicine (Endocrinology) and the Deputy Director of the Yale Center for Analytical Sciences. Dr. Dziura has been the lead biostatistician for federally funded trials including several trials for the Research Units on Pediatric Psychopharmacology (RUPP) Autism Network Trials, Phase II Trial of Teplizumab in Type 1 Diabetes, and the Bright Bodies Lifestyle Intervention Trial for Weight Management in Children. He’s currently the Principle Investigator for the Data Coordinating Center of the RUPP trial investigating the use of Guanfacine in PDD.

Peter Charpentier, Associate Director for Data Management

Pete Charpentier has been involved in data management for epidemiological and clinical studies for more than 35 years. He has been responsible for data management activities for the Claude D. Pepper Older Americans Independence Center at Yale since its inception in 1992, and since 2002 he has been the Director of its Data Management and Informatics Core (DMIC). In addition to his research support leadership role, he participates in database application development projects, working primarily in SAS, MySQL, SQL Server, PHP, JavaScript and MSAccess/VBA. He currently serves as lead designer and developer for three patient-oriented clinical guidance web applications based on research conducted by Program on Aging Faculty Drs. Terri Fried and Liana Fraenkel. He is the development team leader for a 70-site multicenter study, Risk Stratification in Older Adults with Acute Myocardial Infarction (SILVER-AMI; Dr. Sarwat Chaudhry).

Heather G. Allore, PhD

Heather Allore's research is focused on issues related to the design and analysis of studies of multi-component interventions and studies of multifactorial geriatric health conditions and multiple chronic conditions. She develops strategies for handling missing data or competing risks which result in the primary outcome not being observed that frequently occurs in studies of older persons. She is the founder of “Gerontologic Biostatistics” that focuses on statistical and epidemiologic methodology development in aging research. This discipline trains biostatisticians for conducting collaborative research with clinical investigators in geriatrics and gerontology and provides the basis for the development of new statistical methodologies. Methods include: longitudinal modeling of trajectories, extended Cox models for state transitions in geriatrics, such as frailty and disability that consist of multiple discrete states in which both onset and recovery are possible, and determining the mechanisms of action of an effective multi-component intervention. Most recently, the use of joint modeling to account for deaths in longitudinal studies of geriatric outcomes.

Cynthia Brandt, PhD

Prof. Cynthia Brandt has been involved in a wide range of clinical informatics activities at Yale, including working closely with clinical and translational researchers for many years and establishing a strong set of collaborations. She is Director of a postdoctoral training program in Medical Informatics at West Haven VA, and also plays a major mentoring and teaching role within Yale's NIH-supported Biomedical Informatics training activities (which are closely integrated with those at the VA). She is PI of several grants at the West Haven VA, is Co-Director of Yale's Clinical and Translational Award (CTSA) Biomedical Informatics activities at the Yale Center for Clinical Investigation (YCCI) and is Director of Biomedical Informatics at the Yale Cancer Center. She has collaborated with many investigators’ research projects, many of which are externally funded. She also plays a major national role in the field of Biomedical Informatics activities, with a particular focus on the national VA informatics community.