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R3EDI HIV Implementation Science Hub

Rigorous, Rapid and Relevant Evidence aDaptation and Implementation (R3EDI) for Ending the HIV Epidemic (EHE)

Renewing the R3EDI commitment at Yale in supporting community-engaged research through advanced implementation science methods.

2025-2030

The R3EDI Hub at Yale is supported by the National Institute of Allergy and Infectious Diseases (NIAID) under a renewed, five year grant to advance implementation science methods and strengthen community-engaged research across all 57 Ending the HIV Epidemic (EHE) jurisdictions.

The R3EDI Hub is part of a nationwide resource and consultation network, the Capacity-building Hubs to Enhance the Science of HIV Implementation REsearch (CHESHIRE) network, that operates in collaboration with a single U.S. coordination, consultation, and data management center, the HIV Implementation Science Coordination Initiative (ISCI) at Northwestern University. Each of the eight hubs delivers technical assistance, webinars, workshops, and mentoring to assigned project teams proposing and conducting EHE-relevant research, as well as additional HIV researchers and implementing partners in multiple EHE regions.

The focus of the R3EDI at Yale is on:

1) Advanced quantitative and qualitative Implementation Science methods

2) Community-engaged research (CEnR)

These two focus areas draw on expertise at the Yale School of Public Health’s Center for Methods in Implementation and Prevention Science (CMIPS) and Center for Interdisciplinary Research on AIDS (CIRA) to advance implementation science and community-engaged approaches in EHE regions.

Based on needs identified through prior EHE support, we have assembled an exceptional team to provide technical assistance and technical resources in the following areas, including:

  • Community-Based Participatory Research (CBPR) Accelerator
  • Implementing Partners Community of Practice (CoP)
  • Social Determinants of Health database covering all 57 EHE jurisdictions
  • Community-facing dissemination templates
  • Multi-site research within the CHESHIRE Network
  • HIV Visiting Scholars Program

What we aim to achieve

  • 1. Tailored Technical Assistance

    Implementation Science...
    ...Study Designs
    ...Frameworks
    ...Strategies
    ...Measures
    ...Outcomes
    ...Mentoring
    ...Partnership Formation & Sustainment

    for designated EHE researchers and implementers.

  • 2. Technical Resources, Systemic Reviews, & Evaluations

    Implementation Science...
    ...Webinars
    ...Workshops
    ...Reference Materials
    ...Systemic Reviews
    ...Social Determinants of Health Database
    ...Evaluations of Technical Resources

  • 3. CHESHIRE Network & ISCI

    Implementation Science...

    ...Strategic & Technical Leadership Collaboration

2020-2025

R3EDI was established at the Yale School of Public Health and CIRA through an award from the National Institute of Mental Health (NIH) to Dr. Donna Spiegelman as one of five Implementation Science Technical Assistance hubs. Initially funded as one-year supplements, these hubs were designed to catalyze the Ending the HIV Epidemic: A Plan for America (EHE) by synthesizing knowledge across projects and strengthening implementation science research and collaborations. The EHE initiative sets a bold vision to end the HIV epidemic as a public health threat by ensuring that all Americans have access to innovative prevention and treatment tools, beginning in the 57 geographic areas where 80% of new HIV infections occur.

During this period, R3EDI supported 20 EHE projects across 11 states, including New York, New Jersey, Pennsylvania, Illinois, Florida, Georgia, Alabama, Mississippi, Texas, and California.

Developed to connect researchers and projects nationwide, offering expert support, shared tools, and streamlined data to drive impact.

Contact the R3EDI HIV Implementation Science Hub