Yong Kong, PhD
Senior Research ScientistDownloadHi-Res Photo
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Biostatistics
Primary
Additional Titles
Associate Director, Bioinformatics Resource at W.M. Keck Foundation Biotechnology Laboratory
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Appointments
Biostatistics
Primary
Additional Titles
Associate Director, Bioinformatics Resource at W.M. Keck Foundation Biotechnology Laboratory
Contact Info
Appointments
Biostatistics
Primary
Additional Titles
Associate Director, Bioinformatics Resource at W.M. Keck Foundation Biotechnology Laboratory
Contact Info
About
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Titles
Senior Research Scientist
Associate Director, Bioinformatics Resource at W.M. Keck Foundation Biotechnology Laboratory
Appointments
Biostatistics
Senior Research ScientistPrimary
Other Departments & Organizations
Education & Training
- PhD
- Washington University School of Medicine (1997)
Research
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Overview
Medical Research Interests
Information Science; Mathematical Computing
Public Health Interests
Infectious Diseases
ORCID
0000-0002-2881-5274
Research at a Glance
Yale Co-Authors
Frequent collaborators of Yong Kong's published research.
Publications Timeline
A big-picture view of Yong Kong's research output by year.
Melinda Pettigrew, PhD
Akiko Iwasaki, PhD
Hongyu Zhao, PhD
Jiye Kwon, MPH
Martina Wade
Alexej Abyzov, PhD
89Publications
6,384Citations
Publications
2026
Rhinovirus triggers distinct host responses through differential engagement of epithelial innate immune signaling
Wang B, Amat J, Mihaylova V, Kong Y, Wang G, Foxman E. Rhinovirus triggers distinct host responses through differential engagement of epithelial innate immune signaling. 2026, 1: 100001. DOI: 10.1016/j.cpblue.2025.100001.Peer-Reviewed Original ResearchThis study investigates how rhinoviruses, common cold viruses, trigger distinct immune responses in nasal cells, identifying interferons as protective and NLRP1 as a target for reducing harmful inflammation.
2025
Promotion of a new gap junction gene Cx46 (GJA3) expression in the cochlea after Cx26 (GJB2) deficiency
Zhai T, Chen J, Kong Y, Liang C, Zhao H. Promotion of a new gap junction gene Cx46 (GJA3) expression in the cochlea after Cx26 (GJB2) deficiency. Hearing Research 2025, 468: 109454. PMID: 41115329, PMCID: PMC12645451, DOI: 10.1016/j.heares.2025.109454.Peer-Reviewed Original ResearchCitationsAltmetricMicrobiome signatures of Clostridioides difficile toxin production and toxin gene presence: a shotgun metagenomic approach
Kwon J, Correa M, Kong Y, Pelletiers W, Wade M, Olson D, Pettigrew M. Microbiome signatures of Clostridioides difficile toxin production and toxin gene presence: a shotgun metagenomic approach. MSphere 2025, 10: e00435-25. PMID: 40996044, PMCID: PMC12570482, DOI: 10.1128/msphere.00435-25.Peer-Reviewed Original ResearchCitationsHigh MGMT expression identifies aggressive colorectal cancer with distinct genomic features and immune evasion properties
Zhang J, Rajendran B, Desai S, Gibson J, DiPalermo J, LoRusso P, Kong Y, Zhao H, Cecchini M, Schalper K. High MGMT expression identifies aggressive colorectal cancer with distinct genomic features and immune evasion properties. Journal For ImmunoTherapy Of Cancer 2025, 13: e011653. PMID: 40935566, PMCID: PMC12506448, DOI: 10.1136/jitc-2025-011653.Peer-Reviewed Original ResearchThis study shows that high MGMT expression in colorectal cancer is linked to aggressive behavior, distinct genomic features, immune evasion, and shorter survival, highlighting its potential as a biomarker for prognosis and therapeutic targeting.On the Joint Distributions of Increasing and Decreasing Successions of Arbitrary Multisets
Kong Y. On the Joint Distributions of Increasing and Decreasing Successions of Arbitrary Multisets. Methodology And Computing In Applied Probability 2025, 27: 57. DOI: 10.1007/s11009-025-10186-2.Peer-Reviewed Original ResearchHost-pathogen interaction profiling of nontypeable Haemophilus influenzae and Moraxella catarrhalis coinfection of bronchial epithelial cells
D’Mello A, Murphy T, Wade M, Kirkham C, Kong Y, Tettelin H, Pettigrew M. Host-pathogen interaction profiling of nontypeable Haemophilus influenzae and Moraxella catarrhalis coinfection of bronchial epithelial cells. MSphere 2025, 10: e00242-25. PMID: 40492732, PMCID: PMC12306180, DOI: 10.1128/msphere.00242-25.Peer-Reviewed Original ResearchCitationsCutaneous Lupus Features Specialized Stromal Niches and Altered Retroelement Expression
Gehlhausen J, Kong Y, Baker E, Ramachandran S, Koumpouras F, Ko C, Vesely M, Little A, Damsky W, King B, Iwasaki A. Cutaneous Lupus Features Specialized Stromal Niches and Altered Retroelement Expression. Journal Of Investigative Dermatology 2025, 145: 3011-3024.e11. PMID: 40409678, PMCID: PMC12354343, DOI: 10.1016/j.jid.2025.04.033.Peer-Reviewed Original ResearchCitationsAltmetricProspective comparison of the digestive tract resistome and microbiota in cattle raised in grass-fed versus grain-fed production systems
Kwon J, Tanner W, Kong Y, Wade M, Bitler C, Chiavegato M, Pettigrew M. Prospective comparison of the digestive tract resistome and microbiota in cattle raised in grass-fed versus grain-fed production systems. MSphere 2025, 10: e00738-24. PMID: 39950811, PMCID: PMC11934311, DOI: 10.1128/msphere.00738-24.Peer-Reviewed Original ResearchCitations
2024
Recurrence solution of monomer-polymer models on two-dimensional rectangular lattices
Kong Y. Recurrence solution of monomer-polymer models on two-dimensional rectangular lattices. Physical Review E 2024, 110: 054135. PMID: 39690661, DOI: 10.1103/physreve.110.054135.Peer-Reviewed Original ResearchAltmetricThe amalgam of naive CD4+ T cell transcriptional states is reconfigured by helminth infection to dampen the amplitude of the immune response
Even Z, Meli A, Tyagi A, Vidyarthi A, Briggs N, de Kouchkovsky D, Kong Y, Wang Y, Waizman D, Rice T, De Kumar B, Wang X, Palm N, Craft J, Basu M, Ghosh S, Rothlin C. The amalgam of naive CD4+ T cell transcriptional states is reconfigured by helminth infection to dampen the amplitude of the immune response. Immunity 2024, 57: 1893-1907.e6. PMID: 39096910, PMCID: PMC11421571, DOI: 10.1016/j.immuni.2024.07.006.Peer-Reviewed Original ResearchCitationsAltmetric
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News
- January 23, 2026Source: BBC Radio The Naked Scientists Podcast
BBC Radio: Nose-in-a-dish: Scientists recreate common cold in culture
- January 20, 2026Source: Yale News
Why the Same Cold Can Be a Sniffle for Some and a Crisis for Others
- January 08, 2025Source: Yale News
Say Hello to Emo and Punk From the Ancient Seas
- June 08, 2016
Constipated? Study finds surprising cause
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