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Denise Esserman, PhD

Professor of Biostatistics
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Titles

Professor of Biostatistics

Biography

Denise Esserman joined the Yale School of Public Health faculty in 2014 as an associate professor of biostatistics. She is interested in methods related to clustered randomized trials and the impact of the ICC and other factors on calculating sample size. As a member of the Yale Center for Analytical Sciences, she collaborates with a number of departments at the Yale School of Medicine, including the Clinical and Translational Science Award Program, Patient-Centered Outcomes Research Institute, and the Cancer Center. She has reviewed articles for the American Journal of Epidemiology, Arteriosclerosis, Thrombosis and Vascular Biology; Statistics in Biopharmaceutical Research; Clinical Trials; and Obesity. Esserman earned her doctorate at Columbia University and has since taught at the University of North Carolina, Chapel Hill.

Last Updated on April 07, 2025.

Appointments

Other Departments & Organizations

Education & Training

PhD
Columbia University (2006)
MS
University of Georgia (2001)

Research

Overview

Medical Research Interests

Biostatistics; Longitudinal Studies; Public Health; Randomized Controlled Trial; Sampling Studies

Research Projects

Research at a Glance

Yale Co-Authors

Frequent collaborators of Denise Esserman's published research.

Publications

2026

  • The Veteran Affairs’ Whole Health Approach for Chronic Pain Management
    Seal K, Morasco B, Martin A, Reddy K, Van Iseghem T, Bolton R, Bokhour B, Murphy J, Denneson L, Esserman D, Buta E, Purcell N, Bertenthal D, Painter J, Abadjian L, Moore L, Chan A, McCamish N, Maguen S, Neylan T, Gibson C, Becker W, Adams M, Allen R, Ankawi B, Bailey D, Bay W, Beglane M, Berry-Hyatt T, Bess C, Blankenship A, Blankenship E, Borsari B, Burgo L, Burton C, Cagnina M, Chadwell R, Chun V, Cline B, Collins D, Cristoferi K, Dante G, Dayton-Keyhoe A, DeBar L, DeRonne B, Dougherty J, Edmond S, Eichelsdoerfer E, Etzel B, Fabian E, Feinberg T, Frank J, Gagnon T, Garvey C, George K, Greaves D, Greene C, Gregg E, Guo L, Hagedorn H, Hardaway A, Haywood C, Hildebrand C, Hill L, Hillgren K, Hixson J, Hokazano A, Horn J, Hubbard A, Hudson T, Huffer M, Ibarra J, Jacobson C, Jeffries J, Jenkins D, Jones M, Joseph J, Khanna M, Klayman J, Krebs E, Krishnaswamy A, Kuhn A, Lederer V, Lee T, Lisi A, Lucas L, Mack J, Majoris N, Makonnen R, Mathias M, Mazzone K, Miller E, Morgan C, Munusami M, Nguyen Y, Nieves Y, Noack A, Noonan K, Palyo S, Parker J, Parrilla D, Pierce W, Pitts S, Prasad L, Pyne J, Raciborski R, Ramirez T, Rankin S, Richards L, Roca H, Rodenkirch I, Rodriguez Y, Rudroff K, Saeed A, Seidel I, Sewell K, Shah R, Sivilich H, Suitter J, Torres R, Valenti A, Vannier R, Vassilieva S, Wells M, Wentross J, Wesolowicz D, Woodruff N, Yap E, Yeung C, Ying A, Zuniga S. The Veteran Affairs’ Whole Health Approach for Chronic Pain Management. JAMA: The Journal Of The American Medical Association 2026, 335: 1774-1786. PMID: 42054020, PMCID: PMC13130068, DOI: 10.1001/jama.2026.5006.
    Peer-Reviewed Original Research
  • A Cluster Randomized Trial of a Vaccination Communication Educational Intervention: Impact on COVID-19 Vaccine Uptake in Veterans
    Seal K, Kaplan A, Manuel J, Bertenthal D, Purcell N, DeRonne B, Oliver K, Esserman D, McCamish N, Mesidor M, Griffin B, Borsari B, Woodruff N, Usman H, Pyne J. A Cluster Randomized Trial of a Vaccination Communication Educational Intervention: Impact on COVID-19 Vaccine Uptake in Veterans. Journal Of General Internal Medicine 2026, 41: 2217-2226. PMID: 41680545, PMCID: PMC13241570, DOI: 10.1007/s11606-026-10209-9.
    Peer-Reviewed Original Research
  • A joint distribution for indexes of extremes with applications to climate change
    Yu C, Kane M, Blaha O, Wei W, Esserman D, Zelterman D. A joint distribution for indexes of extremes with applications to climate change. Statistics And Its Interface 2026, 19: 197-209. DOI: 10.4310/sii.260108021930.
    Peer-Reviewed Original Research
    This study investigates trends in extreme temperature records in Annapolis, Maryland, showing for the 365 calendar days, record highs occur more recently than record lows, indicating warming trends.
    Full Summary

2025

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Locations

  • 300 George Street

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    Ste 555

    New Haven, CT 06511

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