2024
Temporal trends in population attributable fractions of modifiable risk factors for dementia: a time-series study of the English Longitudinal Study of Ageing (2004–2019)
Chen S, Underwood B, Cardinal R, Chen X, Chen S, Amin J, Jin H, Huang J, Mueller C, Yan L, Brayne C, Kuper H. Temporal trends in population attributable fractions of modifiable risk factors for dementia: a time-series study of the English Longitudinal Study of Ageing (2004–2019). BMC Medicine 2024, 22: 268. PMID: 38926751, PMCID: PMC11210022, DOI: 10.1186/s12916-024-03464-2.Peer-Reviewed Original ResearchConceptsPopulation attributable fractionModifiable risk factorsEnglish Longitudinal Study of AgeingOverall PAFLongitudinal Study of AgingEnglish Longitudinal StudyPhysical inactivitySocioeconomic statusStudy of AgingLower educationDementia riskSocial isolationAttributable fractionHearing lossRisk factorsTargeted public health strategiesTraumatic brain injuryProportion of dementiaDeterminants of dementiaSocioeconomic status categoriesEffective public health policiesDevelopment of evidence-basedPublic health strategiesPublic health policiesTime-series study
2022
Life course traumas and cardiovascular disease—the mediating role of accelerated aging
Cao X, Zhang J, Ma C, Li X, Kuo C, Levine ME, Hu G, Allore H, Chen X, Wu X, Liu Z. Life course traumas and cardiovascular disease—the mediating role of accelerated aging. Annals Of The New York Academy Of Sciences 2022, 1515: 208-218. PMID: 35725988, PMCID: PMC10145586, DOI: 10.1111/nyas.14843.Peer-Reviewed Original ResearchAmerican Older Adults in COVID-19 Times: Vulnerability Types, Aging Attitudes, and Emotional Responses
Fu M, Guo J, Chen X, Han B, Ahmed F, Shahid M, Zhang Q. American Older Adults in COVID-19 Times: Vulnerability Types, Aging Attitudes, and Emotional Responses. Frontiers In Public Health 2022, 9: 778084. PMID: 35211452, PMCID: PMC8860986, DOI: 10.3389/fpubh.2021.778084.Peer-Reviewed Original ResearchConceptsEmotional responsesNegative emotionsOlder adultsNegative Affect ScheduleLatent class analysisOlder adults' vulnerabilityAmerican Older AdultsPositive emotionsEmotional experienceInternational PositiveOwn agingAdult vulnerabilityVulnerability of individualsEmotionsDual vulnerabilityVulnerable older adultsAttitudesAdultsClass analysisPandemic contextIndividualsVulnerability typesBeingVulnerable counterpartsVulnerability
2020
Understanding Health and Social Challenges for Aging and Long-Term Care in China
Yang W, Wu B, Tan SY, Li B, Lou VWQ, Chen Z, Chen X, Fletcher JR, Carrino L, Hu B, Zhang A, Hu M, Wang Y. Understanding Health and Social Challenges for Aging and Long-Term Care in China. Research On Aging 2020, 43: 127-135. PMID: 32677535, PMCID: PMC7961665, DOI: 10.1177/0164027520938764.Peer-Reviewed Original Research
2019
Associations of genetics, behaviors, and life course circumstances with a novel aging and healthspan measure: Evidence from the Health and Retirement Study
Liu Z, Chen X, Gill TM, Ma C, Crimmins EM, Levine ME. Associations of genetics, behaviors, and life course circumstances with a novel aging and healthspan measure: Evidence from the Health and Retirement Study. PLOS Medicine 2019, 16: e1002827. PMID: 31211779, PMCID: PMC6581243, DOI: 10.1371/journal.pmed.1002827.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseArtery diseasePhenotypic agingUS older adultsSelf-reported circumstancesRetirement StudyLife course circumstancesAssociation of geneticMorbidity riskMultivariable associationsPotential policy targetsRetrospective natureAdulthood circumstancesPhenotypic AgeAdulthood adversityGenetic predispositionHealth behaviorsSocioenvironmental circumstancesUS populationOlder adultsPotential interventionsDisadvantaged subpopulationsGenetic riskGenetic scoreUS Health