2024
Temporal trends in population attributable fractions of modifiable risk factors for dementia: a time-series study of the English Longitudinal Study of Ageing (2004–2019)
Chen S, Underwood B, Cardinal R, Chen X, Chen S, Amin J, Jin H, Huang J, Mueller C, Yan L, Brayne C, Kuper H. Temporal trends in population attributable fractions of modifiable risk factors for dementia: a time-series study of the English Longitudinal Study of Ageing (2004–2019). BMC Medicine 2024, 22: 268. PMID: 38926751, PMCID: PMC11210022, DOI: 10.1186/s12916-024-03464-2.Peer-Reviewed Original ResearchConceptsPopulation attributable fractionModifiable risk factorsEnglish Longitudinal Study of AgeingOverall PAFLongitudinal Study of AgingEnglish Longitudinal StudyPhysical inactivitySocioeconomic statusStudy of AgingLower educationDementia riskSocial isolationAttributable fractionHearing lossRisk factorsTargeted public health strategiesTraumatic brain injuryProportion of dementiaDeterminants of dementiaSocioeconomic status categoriesEffective public health policiesDevelopment of evidence-basedPublic health strategiesPublic health policiesTime-series study
2022
The whole-of-society approach of mass COVID-19 vaccination in China: a qualitative study
Wang Q, Qu Z, Tu S, Chen X, Hou Z. The whole-of-society approach of mass COVID-19 vaccination in China: a qualitative study. Health Research Policy And Systems 2022, 20: 142. PMID: 36585666, PMCID: PMC9802023, DOI: 10.1186/s12961-022-00947-7.Peer-Reviewed Original ResearchConceptsSociety approachNon-health sectorsKey informant interviewsSemi-structured interviewsGovernment engagementThematic analysis approachPolicy documentsGovernance perspectiveHealth systems frameworkCOVID-19 vaccinationInformant interviewsService deliveryVaccination coverageQualitative studySystem strengtheningHealth workforceBackgroundMany countriesFinancing channelsCOVID-19 pandemicVaccination service deliveryCountriesVaccination systemDigital information systemsOlder adultsImplementation experienceProjecting Long-Term Care Costs for Home and Community-Based Services in China from 2005 to 2050
Jin H, Su Y, Ping Y, Pickersgill S, Chen X, Liu X, Watkins D, Li Y, Liu H, Wu C. Projecting Long-Term Care Costs for Home and Community-Based Services in China from 2005 to 2050. Journal Of The American Medical Directors Association 2022, 24: 228-234. PMID: 36502859, PMCID: PMC10134410, DOI: 10.1016/j.jamda.2022.11.005.Peer-Reviewed Original ResearchAssociation of Unhealthy Lifestyle and Childhood Adversity With Acceleration of Aging Among UK Biobank Participants
Yang G, Cao X, Li X, Zhang J, Ma C, Zhang N, Lu Q, Crimmins EM, Gill TM, Chen X, Liu Z. Association of Unhealthy Lifestyle and Childhood Adversity With Acceleration of Aging Among UK Biobank Participants. JAMA Network Open 2022, 5: e2230690. PMID: 36066889, PMCID: PMC9449787, DOI: 10.1001/jamanetworkopen.2022.30690.Peer-Reviewed Original ResearchConceptsOnline mental health surveyMental Health SurveyUnhealthy lifestyleChildhood adversityHealth SurveyAge accelerationChildhood adversity scoreUnhealthy lifestyle scoreRetrospective cohort studyRetrospective cohort analysisBody mass indexUK Biobank participantsCohort studyLifestyle interventionLifestyle scoreSmoking statusMass indexChronic diseasesCohort analysisMAIN OUTCOMEPhysical activityAlcohol consumptionAdversity scoreFormal mediation analysisBiobank participantsDifficulty and help with activities of daily living among older adults living alone during the COVID-19 pandemic: a multi-country population-based study
Chen S, Jones LA, Jiang S, Jin H, Dong D, Chen X, Wang D, Zhang Y, Xiang L, Zhu A, Cardinal RN. Difficulty and help with activities of daily living among older adults living alone during the COVID-19 pandemic: a multi-country population-based study. BMC Geriatrics 2022, 22: 181. PMID: 35246064, PMCID: PMC8894568, DOI: 10.1186/s12877-022-02799-w.Peer-Reviewed Original ResearchConceptsHealth system factorsADL assistanceOlder adultsCOVID-19 pandemicPopulation-based studyLongitudinal cohort studyHealth service expendituresSystem factorsCOVID-19Wealth-related inequalitiesHealth-related indicatorsPandemic-related changesCohort studyADL difficultyEligible peopleBackgroundOlder adultsDaily livingAdultsInternational variationConcentration indexService expendituresPandemicDifficulty statusSex gapUnequal responseAmerican Older Adults in COVID-19 Times: Vulnerability Types, Aging Attitudes, and Emotional Responses
Fu M, Guo J, Chen X, Han B, Ahmed F, Shahid M, Zhang Q. American Older Adults in COVID-19 Times: Vulnerability Types, Aging Attitudes, and Emotional Responses. Frontiers In Public Health 2022, 9: 778084. PMID: 35211452, PMCID: PMC8860986, DOI: 10.3389/fpubh.2021.778084.Peer-Reviewed Original ResearchConceptsEmotional responsesNegative emotionsOlder adultsNegative Affect ScheduleLatent class analysisOlder adults' vulnerabilityAmerican Older AdultsPositive emotionsEmotional experienceInternational PositiveOwn agingAdult vulnerabilityVulnerability of individualsEmotionsDual vulnerabilityVulnerable older adultsAttitudesAdultsClass analysisPandemic contextIndividualsVulnerability typesBeingVulnerable counterpartsVulnerability
2021
Prevalence of Memory-Related Diagnoses Among U.S. Older Adults With Early Symptoms of Cognitive Impairment
Qian Y, Chen X, Tang D, Kelley AS, Li J. Prevalence of Memory-Related Diagnoses Among U.S. Older Adults With Early Symptoms of Cognitive Impairment. The Journals Of Gerontology Series A 2021, 76: 1846-1853. PMID: 33575783, PMCID: PMC8436977, DOI: 10.1093/gerona/glab043.Peer-Reviewed Original Research
2020
How and to what extent can pensions facilitate increased use of health services by older people: evidence from social pension expansion in rural China
Chen S, Chen X, Law S, Lucas H, Tang S, Long Q, Xue L, Wang Z. How and to what extent can pensions facilitate increased use of health services by older people: evidence from social pension expansion in rural China. BMC Health Services Research 2020, 20: 1008. PMID: 33148248, PMCID: PMC7640495, DOI: 10.1186/s12913-020-05831-0.Peer-Reviewed Original ResearchConceptsHealth service utilizationService utilizationHealth servicesOlder peopleFrequency of outpatientInpatient service useHealthcare-seeking behaviorRetirement Longitudinal StudyProportion of peopleTraditional Chinese medicineHealthcare utilisationService useEconomic burdenInpatient servicesAge groupsAdditional economic burdenChina HealthOlder adultsChinese medicineMethodsUsing dataLongitudinal studyOutpatientsRegression analysisState of healthFuzzy regression discontinuity designAttributable risk and economic cost of hospital admissions for mental disorders due to PM2.5 in Beijing
Wu Z, Chen X, Li G, Tian L, Wang Z, Xiong X, Yang C, Zhou Z, Pan X. Attributable risk and economic cost of hospital admissions for mental disorders due to PM2.5 in Beijing. The Science Of The Total Environment 2020, 718: 137274. PMID: 32109812, PMCID: PMC9429815, DOI: 10.1016/j.scitotenv.2020.137274.Peer-Reviewed Original ResearchConceptsHospital admissionAttributable riskMental disordersEconomic burdenSignificant risk increaseMental health statusEffects of PMSubstantial morbidityStratified analysisElderly individualsHealth statusMedical expensesStudy periodAir quality guidelinesRisk increaseAdmissionTime trendsRiskEconomic costsDisordersPossible correlationBurdenAerodynamic diameterExposureDaily increaseLinking early life risk factors to frailty in old age: evidence from the China Health and Retirement Longitudinal Study
Li Y, Xue QL, Odden MC, Chen X, Wu C. Linking early life risk factors to frailty in old age: evidence from the China Health and Retirement Longitudinal Study. Age And Ageing 2020, 49: 208-217. PMID: 31957780, PMCID: PMC7047816, DOI: 10.1093/ageing/afz160.Peer-Reviewed Original ResearchConceptsEarly life risk factorsLife risk factorsRisk factorsChildhood health statusRetirement Longitudinal StudyRisk differenceHealth statusChina HealthOlder ageOlder adultsAbsolute risk differenceCross-sectional studyLongitudinal studyUnfavorable socioeconomic statusLate-life frailtyWorse health conditionsChinese older adultsMiddle-income countriesDevelopment of diseaseHigh riskLower riskRepresentative cohortMultinomial regression modelsHealth conditionsFrailty
2019
Depression in the house: The effects of household air pollution from solid fuel use among the middle-aged and older population in China
Liu Y, Chen X, Yan Z. Depression in the house: The effects of household air pollution from solid fuel use among the middle-aged and older population in China. The Science Of The Total Environment 2019, 703: 134706. PMID: 31731156, PMCID: PMC9420076, DOI: 10.1016/j.scitotenv.2019.134706.Peer-Reviewed Original ResearchConceptsHigher CES-D scoresHousehold air pollutionSolid fuel usersCES-D scoresDepression riskPotential confoundersSolid fuel useEpidemiologic Studies Depression Scale scoreHAP exposureOlder populationFuel usersChronic lung diseaseClean fuel usersDepression Scale scoresPublic health effortsAmbient air pollutionHousehold solid fuel useAdverse health effectsLung diseaseDepression outcomesChronic diseasesCardiovascular diseaseHealth effortsScale scoreHealth statusAssociations of genetics, behaviors, and life course circumstances with a novel aging and healthspan measure: Evidence from the Health and Retirement Study
Liu Z, Chen X, Gill TM, Ma C, Crimmins EM, Levine ME. Associations of genetics, behaviors, and life course circumstances with a novel aging and healthspan measure: Evidence from the Health and Retirement Study. PLOS Medicine 2019, 16: e1002827. PMID: 31211779, PMCID: PMC6581243, DOI: 10.1371/journal.pmed.1002827.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseArtery diseasePhenotypic agingUS older adultsSelf-reported circumstancesRetirement StudyLife course circumstancesAssociation of geneticMorbidity riskMultivariable associationsPotential policy targetsRetrospective natureAdulthood circumstancesPhenotypic AgeAdulthood adversityGenetic predispositionHealth behaviorsSocioenvironmental circumstancesUS populationOlder adultsPotential interventionsDisadvantaged subpopulationsGenetic riskGenetic scoreUS HealthDecomposing inequality in catastrophic health expenditure for self-reported hypertension household in Urban Shaanxi, China from 2008 to 2013: two waves’ cross-sectional study
Si Y, Zhou Z, Su M, Wang X, Lan X, Wang D, Gong S, Xiao X, Shen C, Ren Y, Zhao D, Hong Z, Bian Y, Chen X. Decomposing inequality in catastrophic health expenditure for self-reported hypertension household in Urban Shaanxi, China from 2008 to 2013: two waves’ cross-sectional study. BMJ Open 2019, 9: e023033. PMID: 31076467, PMCID: PMC6528006, DOI: 10.1136/bmjopen-2018-023033.Peer-Reviewed Original ResearchConceptsCatastrophic health expenditurePro-poor inequalityMixed householdsHealth expenditureIncome-related inequalitiesNational Health Services SurveyPocket healthcare expenditureHousehold economic statusFifth National Health Service SurveysHealthcare reformHealth Services SurveyCHE occurrenceHousehold capacityObserved inequalitiesProbit regressionUrban ChinaConcentration indexHouseholdsHealthcare expendituresEconomic statusChina's healthcare reformElderly membersExpenditureInequalityServices Survey
2018
Socio-Economic Inequalities in Tobacco Consumption of the Older Adults in China: A Decomposition Method
Si Y, Zhou Z, Su M, Wang X, Li D, Wang D, He S, Hong Z, Chen X. Socio-Economic Inequalities in Tobacco Consumption of the Older Adults in China: A Decomposition Method. International Journal Of Environmental Research And Public Health 2018, 15: 1466. PMID: 29997376, PMCID: PMC6069145, DOI: 10.3390/ijerph15071466.Peer-Reviewed Original ResearchConceptsTobacco consumptionConcentration indexNon-communicable diseasesTobacco use prevalenceRetirement Longitudinal StudySocio-economic inequalitiesPublic health policyPublic health controlRisk factorsLow educational attainmentHealth controlsChina HealthUse prevalenceHealth policyEducational attainmentOlder AdultsUse quantityLongitudinal studyStrongest predictorPrevalenceAgeGenderSmokersIndexDisease