1993
Effects of timing of methylprednisolone or naloxone administration on recovery of segmental and long-tract neurological function in NASCIS 2.
Bracken M, Holford T. Effects of timing of methylprednisolone or naloxone administration on recovery of segmental and long-tract neurological function in NASCIS 2. Journal Of Neurosurgery 1993, 79: 500-7. PMID: 8410217, DOI: 10.3171/jns.1993.79.4.0500.Peer-Reviewed Original ResearchMeSH KeywordsDrug Administration ScheduleHumansInjury Severity ScoreMethylprednisoloneNaloxoneNervous SystemSpinal Cord InjuriesConceptsNational Acute Spinal Cord Injury StudyNeurological recoveryIncomplete injuriesNeurological functionNaloxone administrationClinical managementAcute Spinal Cord Injury StudySpinal Cord Injury StudyHigh-dose methylprednisoloneLong spinal tractsHours of injuryUltimate therapeutic goalInjury levelConsiderable clinical significanceNarrow treatment windowMethylprednisolone treatmentSpinal tractClinical significanceSegmental functionInjury studiesTherapeutic goalsTreatment windowMethylprednisoloneHigh dosesInjury
1992
A model for estimating level and net severity of spinal cord injuries
Holford T, Bracken M. A model for estimating level and net severity of spinal cord injuries. Statistics In Medicine 1992, 11: 1171-1186. PMID: 1509218, DOI: 10.1002/sim.4780110904.Peer-Reviewed Case Reports and Technical NotesMeSH KeywordsEvaluation Studies as TopicHumansInjury Severity ScoreMotor ActivityNeurologic ExaminationRegression AnalysisReproducibility of ResultsSpinal Cord InjuriesConceptsSpinal cord injuryCord injuryNational Acute Spinal Cord Injury StudyAcute Spinal Cord Injury StudyAcute spinal cord injurySpinal Cord Injury StudyDetailed neurological assessmentNeurologic functionNeurological assessmentMotor assessmentInjury studiesOverall severityInjurySeverityScoresLevelsEpidemiology