2014
Age-Specific Risks of Tuberculosis Infection From Household and Community Exposures and Opportunities for Interventions in a High-Burden Setting
Zelner JL, Murray MB, Becerra MC, Galea J, Lecca L, Calderon R, Yataco R, Contreras C, Zhang Z, Grenfell BT, Cohen T. Age-Specific Risks of Tuberculosis Infection From Household and Community Exposures and Opportunities for Interventions in a High-Burden Setting. American Journal Of Epidemiology 2014, 180: 853-861. PMID: 25190676, PMCID: PMC4188339, DOI: 10.1093/aje/kwu192.Peer-Reviewed Original ResearchConceptsLatent tuberculosis infectionHousehold contactsAge-specific riskYears of ageTuberculosis infectionLarge population-based prospective cohort studyPopulation-based prospective cohort studyHousehold exposureBacillus Calmette-Guérin (BCG) vaccineIncident pulmonary tuberculosisCommunity exposureProspective cohort studyCalmette-Guérin vaccineHigh-burden settingsPublic Health CenterCommunity-based transmissionRisk of infectionCohort studyLTBI prevalencePreventive therapyPulmonary tuberculosisTuberculosis patientsTuberculosis casesHousehold transmissionExcess risk
2013
The Effect of HIV-Related Immunosuppression on the Risk of Tuberculosis Transmission to Household Contacts
Huang CC, Tchetgen ET, Becerra MC, Cohen T, Hughes KC, Zhang Z, Calderon R, Yataco R, Contreras C, Galea J, Lecca L, Murray M. The Effect of HIV-Related Immunosuppression on the Risk of Tuberculosis Transmission to Household Contacts. Clinical Infectious Diseases 2013, 58: 765-774. PMID: 24368620, PMCID: PMC3935504, DOI: 10.1093/cid/cit948.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusHousehold contactsIndex patientsCD4 countTuberculosis patientsTuberculosis transmissionHIV-negative tuberculosis patientsHIV-negative patientsHIV-positive patientsDrug-sensitive tuberculosisTuberculin skin testingTuberculosis infection statusRisk of infectionCoinfected PatientsActive tuberculosisTuberculosis infectionHIV statusSkin testingImmunodeficiency virusRisk factorsRelative riskPatientsTuberculosisInfection statusInfection