2024
Pulsed nicotine infusions as a model for smoking: validating a tool to explore nicotine thresholds in humans
Parida S, MacLean R, Gueorguieva R, Sofuoglu M. Pulsed nicotine infusions as a model for smoking: validating a tool to explore nicotine thresholds in humans. Psychopharmacology 2024, 241: 1915-1922. PMID: 38970644, DOI: 10.1007/s00213-024-06609-6.Peer-Reviewed Original ResearchDiscriminative stimulus effectsAddiction thresholdNicotine doseDiscriminative stimulus effects of nicotineStimulus effects of nicotineNicotine deliveryEffects of nicotineOvernight abstinenceStimulus effectsNicotine infusionSubjective effectsTest sessionsNicotineMethodsEleven participantsInfusion procedureLow dosesParticipantsThreshold doseConclusionsTheseAbstinenceDoseHeart rateInfusionSmokingObjectivesToSmartband-based smoking detection and real-time brief mindfulness intervention: findings from a feasibility clinical trial
Horvath M, Pittman B, O’Malley S, Grutman A, Khan N, Gueorguieva R, Brewer J, Garrison K. Smartband-based smoking detection and real-time brief mindfulness intervention: findings from a feasibility clinical trial. Annals Of Medicine 2024, 56: 2352803. PMID: 38823419, PMCID: PMC11146247, DOI: 10.1080/07853890.2024.2352803.Peer-Reviewed Original ResearchConceptsBrief mindfulness interventionsMindfulness exercisesTreatment startersMindfulness interventionSmoking interventionsOnline mindfulness trainingWhite non-HispanicMindfulness trainingTreatment fidelityFeasibility measuresHelpfulness ratingsNon-HispanicDaily smokersPredicting smokingReduce smokingExerciseSmokingCigarette smokingInterventionLow completenessAdherenceParticipantsSmartbandAcceptanceMindfulness
2023
Randomized Trial of Mindfulness- and Reappraisal-Based Regulation of Craving Training Among Daily Cigarette Smokers
Roos C, Harp N, Vafaie N, Gueorguieva R, Frankforter T, Carroll K, Kober H. Randomized Trial of Mindfulness- and Reappraisal-Based Regulation of Craving Training Among Daily Cigarette Smokers. Psychology Of Addictive Behaviors 2023, 37: 829-840. PMID: 37535555, PMCID: PMC10834831, DOI: 10.1037/adb0000940.Peer-Reviewed Original ResearchCue-induced cravingDaily cigarette smokersGreater reductionSmoking-related imagesRandomized trialsCigarette smokersDaily smokersQuit ratesSmokingLarge effect sizesIntervention phaseIntervention controlCravingSmokersComputerized interventionSignificant increaseCBTEffect sizeEntire studyInterventionControlPostinterventionROCRegulationTrials
2021
The effect of varenicline on smoking and drinking outcomes among Black and White adults with alcohol use disorder and co-occurring cigarette smoking: A secondary analysis of two clinical trials
Haeny AM, Gueorguieva R, Montgomery L, Bold KW, Fucito LM, Wu R, Muvvala SB, Zweben A, O'Malley SS. The effect of varenicline on smoking and drinking outcomes among Black and White adults with alcohol use disorder and co-occurring cigarette smoking: A secondary analysis of two clinical trials. Addictive Behaviors 2021, 122: 106970. PMID: 34216871, PMCID: PMC9426655, DOI: 10.1016/j.addbeh.2021.106970.Peer-Reviewed Original ResearchConceptsEffects of vareniclineAlcohol use disorderCigarette smokingClinical trialsUse disordersWhite adultsEfficacy of vareniclineNumber of drinksVareniclineSmokingPrimary analysisAlcohol treatmentSecondary analysisAlcohol useTrialsBlack participantsDrinking outcomesLinear mixed modelsAdultsWhite peopleWhite participantsMixed modelingCigarettesDisordersTreatment
2020
An integrated behavioural intervention combined with varenicline for heavy-drinking smokers: a randomized pilot study.
Fucito LM, Wu R, O'Malley SS, Hanrahan TH, Ikomi JT, Muvvala S, Carroll KM, Gueorguieva R. An integrated behavioural intervention combined with varenicline for heavy-drinking smokers: a randomized pilot study. The Journal Of Smoking Cessation 2020, 15: 119-127. PMID: 33312238, PMCID: PMC7731353, DOI: 10.1017/jsc.2020.13.Peer-Reviewed Original ResearchFeasibility/acceptabilityHeavy drinking smokersAlcohol counsellingHeavy drinkingBehavioral interventionsPilot studyOpen-label vareniclineRandomized pilot studySignificant health burdenComputer-generated tableTobacco pharmacotherapyHealth burdenQuit ratesPilot trialResearch clinicDrinking reductionsVareniclineBehavioural counsellingAlcohol treatmentCombined smokingMedium effect sizeSmokingSmokersCounsellingDrinking
2018
Craving to Quit: A Randomized Controlled Trial of Smartphone App–Based Mindfulness Training for Smoking Cessation
Garrison KA, Pal P, O’Malley S, Pittman BP, Gueorguieva R, Rojiani R, Scheinost D, Dallery J, Brewer JA. Craving to Quit: A Randomized Controlled Trial of Smartphone App–Based Mindfulness Training for Smoking Cessation. Nicotine & Tobacco Research 2018, 22: 324-331. PMID: 29917096, PMCID: PMC7297096, DOI: 10.1093/ntr/nty126.Peer-Reviewed Original ResearchConceptsMindfulness trainingExperience samplingPreliminary evidenceSmartphone appPoint prevalence abstinence ratesMindfulnessSmoking cessationTreatment startersSmoking ratesGroup differencesGroup interactionCravingStrong positive associationAbstinence ratesTrainingTreatment completionPositive associationControlled TrialsTreat approachSmokingTrialsCigarettesMonthsAppsAssociation
2012
Cigarette Smoking Predicts Differential Benefit from Naltrexone for Alcohol Dependence
Fucito LM, Park A, Gulliver SB, Mattson ME, Gueorguieva RV, O'Malley SS. Cigarette Smoking Predicts Differential Benefit from Naltrexone for Alcohol Dependence. Biological Psychiatry 2012, 72: 832-838. PMID: 22541040, PMCID: PMC3410039, DOI: 10.1016/j.biopsych.2012.03.023.Peer-Reviewed Original ResearchConceptsCigarette smokingAlcohol dependenceBehavioral interventionsAlcohol-dependent smokersCombination of medicationsBaseline demographic differencesPoor treatment outcomesPoor treatment responseDrinking outcomesBetter drinking outcomesSevere alcohol dependenceAlcohol-dependent individualsCigarette intakeAlcohol use outcomesMedical managementPharmacological treatmentTreatment outcomesTreatment responseSmokingSmokersCOMBINE StudyAlcoholism typologyDrinking-related variablesTreatment assignmentNonsmokers