Associations Between Tenofovir Diphosphate in Dried Blood Spots, Impaired Physical Function, and Fracture Risk
Abdo M, Coyle RP, Seifert SM, Castillo-Mancilla JR, Jankowski CM, MaWhinney S, Anderson PL, Erlandson KM. Associations Between Tenofovir Diphosphate in Dried Blood Spots, Impaired Physical Function, and Fracture Risk. Open Forum Infectious Diseases 2020, 8: ofaa577. PMID: 33447638, PMCID: PMC7781095, DOI: 10.1093/ofid/ofaa577.Peer-Reviewed Original ResearchBone mineral densityBody mass indexHip bone mineral densityTFV-DPTotal fat massLean body massPhysical functionFat massTenofovir diphosphateFracture riskHigher oddsHigher TFV-DP levelsLow hip bone mineral densityBlood spotsImpaired physical functionTenofovir diphosphate concentrationsTFV disoproxil fumarateTFV-DP levelsPoor physical functionHuman immunodeficiency virusCross-sectional analysisLogistic regression modelsDried Blood SpotsBody massImmunodeficiency virus