2023
A user-centred implementation strategy for tuberculosis contact investigation in Uganda: protocol for a stepped-wedge, cluster-randomised trial
Katamba A, Gupta A, Turimumahoro P, Ochom E, Ggita J, Nakasendwa S, Nanziri L, Musinguzi J, Hennein R, Sekadde M, Hanrahan C, Byaruhanga R, Yoeli E, Turyahabwe S, Cattamanchi A, Dowdy D, Haberer J, Armstrong-Hough M, Kiwanuka N, Davis J. A user-centred implementation strategy for tuberculosis contact investigation in Uganda: protocol for a stepped-wedge, cluster-randomised trial. BMC Public Health 2023, 23: 1568. PMID: 37592314, PMCID: PMC10436440, DOI: 10.1186/s12889-023-16510-0.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsCognitionContact TracingHumansRandomized Controlled Trials as TopicTuberculosisUgandaConceptsContact investigationClinical effectiveness outcomesPrimary implementation outcomeTB contact investigationTB preventative therapyTB treatment initiationTimely TB diagnosisTrial registrationThe trialTuberculosis contact investigationCluster-randomised trialHigh-burden settingsImplementation-effectiveness trialEvidence-based interventionsUganda National CouncilWorld Health OrganizationProportion of contactsTB evaluationPeer-reviewed journalsMiddle-income countriesTreatment initiationTB diagnosisPreventative therapyUndiagnosed personsInfectious deathSputum samples
2018
Association of Rapid Molecular Testing With Duration of Respiratory Isolation for Patients With Possible Tuberculosis in a US Hospital
Chaisson LH, Duong D, Cattamanchi A, Roemer M, Handley MA, Schillinger D, Sur M, Pham P, Lin MA, Goldman LE, Quan J, Perez S, Healy M, Higashi J, Winston L, Haller B, Luetkemeyer AF, Davis JL. Association of Rapid Molecular Testing With Duration of Respiratory Isolation for Patients With Possible Tuberculosis in a US Hospital. JAMA Internal Medicine 2018, 178: 1380-1388. PMID: 30178007, PMCID: PMC6368387, DOI: 10.1001/jamainternmed.2018.3638.Peer-Reviewed Original ResearchConceptsDiscontinuation of isolationMolecular testing algorithmRespiratory isolationMolecular testingPossible tuberculosisActive tuberculosisPreimplementation periodUS hospitalsZuckerberg San Francisco General HospitalSan Francisco General HospitalGeneXpert MTB/RIFCulture-confirmed tuberculosisPatient-centered evaluationActive pulmonary tuberculosisProportion of patientsProspective cohort studyLength of stayMTB/RIFRapid test resultsRapid molecular testingSputum smear microscopyMolecular testing strategiesHealth care settingsCulture-negative resultsTB-negative patients