2003
The HRAS1 variable number of tandem repeats and risk of breast cancer.
Tamimi RM, Hankinson SE, Ding S, Gagalang V, Larson GP, Spiegelman D, Colditz GA, Krontiris TG, Hunter DJ. The HRAS1 variable number of tandem repeats and risk of breast cancer. Cancer Epidemiology Biomarkers & Prevention 2003, 12: 1528-30. PMID: 14693748.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAllelesBreast NeoplasmsCase-Control StudiesDNA, NeoplasmFemaleGenes, rasGenetic Predisposition to DiseaseGenotypeHumansLogistic ModelsMiddle AgedMinisatellite RepeatsPolymerase Chain ReactionPolymorphism, GeneticProbabilityPrognosisReference ValuesRisk AssessmentSensitivity and SpecificityTandem Repeat SequencesConceptsHealth Study cohortBreast cancer casesBreast cancerCancer casesNurses' Health Study cohortIncident breast cancer casesHRAS1 VNTRHRAS1 variable numberBreast cancer riskCase-control studyGene-dose effectRare HRAS1 allelesMenopausal statusStudy cohortCancer riskOverall associationCancerHRAS1 allelesRiskRare allelesAssociationCommon allelesAllelesVariable numberCohort
2002
The androgen receptor CAG repeat polymorphism and risk of breast cancer in the Nurses' Health Study.
Haiman CA, Brown M, Hankinson SE, Spiegelman D, Colditz GA, Willett WC, Kantoff PW, Hunter DJ. The androgen receptor CAG repeat polymorphism and risk of breast cancer in the Nurses' Health Study. Cancer Research 2002, 62: 1045-9. PMID: 11861380.Peer-Reviewed Original ResearchMeSH KeywordsAdultAllelesBreast NeoplasmsCase-Control StudiesFemaleGenetic Predisposition to DiseaseHumansMiddle AgedPolymorphism, GeneticProspective StudiesReceptors, AndrogenRepetitive Sequences, Nucleic AcidConceptsFirst-degree family historyBreast cancer riskHealth Study cohortAndrogen receptorBreast cancerCancer riskFamily historyAR genotypeCaucasian womenHormone levelsHealth StudyNurses' Health Study cohortBreast cancer risk factorsEndogenous steroid hormone levelsNurses' Health StudyCancer risk factorsPostmenopausal Caucasian womenCase-control studyAndrogen receptor genotypeAndrogen receptor CAGAndrogen receptor allelesSteroid hormone levelsShort alleleLong alleleSignificant positive association
2001
House Dust Endotoxin and Wheeze in the First Year of Life
PARK J, GOLD D, SPIEGELMAN D, BURGE H, MILTON D. House Dust Endotoxin and Wheeze in the First Year of Life. American Journal Of Respiratory And Critical Care Medicine 2001, 163: 322-328. PMID: 11179100, DOI: 10.1164/ajrccm.163.2.2002088.Peer-Reviewed Original ResearchMeSH KeywordsAllergensAsthmaCohort StudiesDustEndotoxinsFemaleGenetic Predisposition to DiseaseHumansInfantInfant, NewbornMalePregnancyRespiratory SoundsRisk FactorsConceptsElevated endotoxinEndotoxin exposureMultivariate modelLower respiratory illnessMultivariate relative riskHistory of asthmaLow birth weightSignificant univariate associationsFirst yearHouse dust endotoxinRoom dustRace/ethnicityMaternal asthmaPrimary outcomeRespiratory illnessAbove covariatesBirth weightDust endotoxinRelative riskCockroach allergensUnivariate associationsFamilial predispositionBedroom floorWheezeBirth cohort