2004
Reproductive History and Endometriosis Among Premenopausal Women
Missmer SA, Hankinson SE, Spiegelman D, Barbieri RL, Malspeis S, Willett WC, Hunter DJ. Reproductive History and Endometriosis Among Premenopausal Women. Obstetrics And Gynecology 2004, 104: 965-974. PMID: 15516386, DOI: 10.1097/01.aog.0000142714.54857.f8.Peer-Reviewed Original ResearchConceptsHealth Study II cohortParous womenNurses' Health Study II cohortShorter menstrual cyclesProportional hazards modelLifetime durationEarly ageShorter cycle lengthsPast infertilityPremenopausal womenNulliparous womenProspective dataMenstrual cycleReproductive factorsLiveborn childrenHazards modelLast birthEndometriosisGreater incidenceReproductive historyCycle regularityWomenAnatomical changesCalendar timeCycle lengthEarly life menstrual characteristics and pregnancy experiences among women with and without major depression: the Harvard study of moods and cycles
Harlow BL, Cohen LS, Otto MW, Spiegelman D, Cramer DW. Early life menstrual characteristics and pregnancy experiences among women with and without major depression: the Harvard study of moods and cycles. Journal Of Affective Disorders 2004, 79: 167-176. PMID: 15023491, DOI: 10.1016/s0165-0327(02)00459-7.Peer-Reviewed Original ResearchConceptsRisk of depressionMajor depressionHeavy menstrual flowMenstrual cycle characteristicsMonths of breastfeedingNumber of livebirthsYears of menstruationCurrent major depressionHistory of depressionMost risk estimatesPopulation-based sampleYears of ageWomen 36Menstrual characteristicsGynecological careStudy enrollmentDecreased riskMenstrual flowMenstrual cyclePostpartum periodCycle irregularityPsychiatric sequelaePregnancy experiencePremenstrual dysphoriaMultiple abortionsPlasma Lipid and Lipoprotein Levels during the Follicular and Luteal Phases of the Menstrual Cycle
Barnett JB, Woods MN, Lamon-Fava S, Schaefer EJ, McNamara JR, Spiegelman D, Hertzmark E, Goldin B, Longcope C, Gorbach SL. Plasma Lipid and Lipoprotein Levels during the Follicular and Luteal Phases of the Menstrual Cycle. The Journal Of Clinical Endocrinology & Metabolism 2004, 89: 776-782. PMID: 14764796, DOI: 10.1210/jc.2003-030506.Peer-Reviewed Original ResearchConceptsMenstrual cycle phaseLuteal phasePremenopausal womenFollicular phaseMenstrual cycleTotal cholesterol/high-density lipoprotein cholesterolLow-density lipoprotein cholesterol levelsHigh-density lipoprotein cholesterolCoronary heart disease riskTotal cholesterol/HDLPremenopausal Caucasian womenLipoprotein cholesterol levelsHeart disease riskBody mass indexCholesterol/HDLLevels of LDLSex hormone levelsLevels of estradiolLipoprotein cholesterolLipoprotein levelsMass indexEstrogen levelsLipoprotein profilePlasma lipidsCholesterol levels
1999
Reproducibility of plasma and urinary sex hormone levels in premenopausal women over a one-year period.
Michaud DS, Manson JE, Spiegelman D, Barbieri RL, Sepkovic DW, Bradlow HL, Hankinson SE. Reproducibility of plasma and urinary sex hormone levels in premenopausal women over a one-year period. Cancer Epidemiology Biomarkers & Prevention 1999, 8: 1059-64. PMID: 10613337.Peer-Reviewed Original ResearchConceptsPremenopausal womenIntraclass correlation coefficientLuteal phaseHormone levelsBlood samplesEndogenous sex steroid hormonesUrinary sex hormone levelsUrinary sex hormonesUrinary estrogen metabolitesSex hormone levelsSex steroid hormonesSets of bloodSingle blood sampleHigh intraclass correlation coefficientsLuteal phase samplesPlasma estrogenMenstrual cycleSex hormonesPlasma estradiolBreast cancerEstrogen metabolitesEstrone sulfateUrinary 2One-year periodSteroid hormones
1998
Menstrual Cycle Characteristics and History of Ovulatory Infertility in Relation to Breast Cancer Risk in a Large Cohort of US Women
Garland M, Hunter D, Colditz G, Manson J, Stampfer M, Spiegelman D, Speizer F, Willett W. Menstrual Cycle Characteristics and History of Ovulatory Infertility in Relation to Breast Cancer Risk in a Large Cohort of US Women. American Journal Of Epidemiology 1998, 147: 636-643. PMID: 9554602, DOI: 10.1093/oxfordjournals.aje.a009504.Peer-Reviewed Original ResearchConceptsMultivariate relative riskHealth Study IIMenstrual cycle characteristicsBreast cancer riskRelative riskOvulatory infertilityBreast cancerCancer riskLonger menstrual cycle lengthNurses' Health Study IICycle lengthUsual cycle lengthProspective cohort studyMenstrual cycle lengthOvulatory menstrual cyclesCohort studyBaseline questionnaireMenstrual cycleLarge cohortProtective effectUS womenAge 18Study IIInfertilityCycle characteristics
1996
Hormone Levels During Dietary Changes in Premenopausal African-American Women
Woods M, Barnett J, Spiegelman D, Trail N, Hertzmark E, Longcope C, Gorbach S. Hormone Levels During Dietary Changes in Premenopausal African-American Women. Journal Of The National Cancer Institute 1996, 88: 1369-1374. PMID: 8827014, DOI: 10.1093/jnci/88.19.1369.Peer-Reviewed Original ResearchConceptsSerum hormone levelsSex hormone-binding globulinAfrican American womenCaucasian womenHormone levelsControl dietFree E2Menstrual cycleSurvival ratePremenopausal African American womenClinical study unitSerum hormone valuesTwo-sided statistical testsEndogenous sex hormonesHormone-binding globulinTypical North American dietSame control dietSignificant lower levelsTypes of cancerNorth American dietHigh-fiber dietConcentrations of estroneSHBG levelsSerum estrogenAndrostenedione levels
1995
Changes in plasma lipoprotein concentrations and composition in response to a low-fat, high-fiber diet are associated with changes in serum estrogen concentrations in premenopausal women
Schaefer E, Lamon-Fava S, Spiegelman D, Dwyer J, Lichtenstein A, McNamara J, Goldin B, Woods M, Morrill-LaBrode A, Hertzmark E, Longcope C, Gorbach S. Changes in plasma lipoprotein concentrations and composition in response to a low-fat, high-fiber diet are associated with changes in serum estrogen concentrations in premenopausal women. Metabolism 1995, 44: 749-756. PMID: 7783659, DOI: 10.1016/0026-0495(95)90188-4.Peer-Reviewed Original ResearchConceptsHigh-fiber dietLuteal phasePremenopausal womenTotal cholesterolPlasma lipidsBaseline dietFollicular phaseHigh-density lipoprotein cholesterol concentrationsSerum sex hormone concentrationsLow-density lipoprotein cholesterolNormal premenopausal womenLipoprotein cholesterol concentrationsSex hormone concentrationsSerum estrogen concentrationsPlasma lipoprotein concentrationsSerum estrone sulphate concentrationsEstrone sulfate concentrationsLow-density lipoproteinLipoprotein cholesterolLipoprotein levelsSerum hormonesLipoprotein concentrationsMenstrual cyclePlasma triglyceridesTG concentrations
1994
The effect of dietary fat and fiber on serum estrogen concentrations in premenopausal women under controlled dietary conditions
Goldin B, Woods M, Spiegelman D, Longcope C, Morrill‐LaBrode A, Dwyer J, Gualtieri L, Hertzmark E, Gorbach S. The effect of dietary fat and fiber on serum estrogen concentrations in premenopausal women under controlled dietary conditions. Cancer 1994, 74: 1125-1131. PMID: 8039147, DOI: 10.1002/1097-0142(19940801)74:3+<1125::aid-cncr2820741521>3.0.co;2-5.Peer-Reviewed Original ResearchConceptsPremenopausal womenSerum concentrationsSex hormonesDietary fatEstrone sulfateSerum sex hormonesSerum estrogen concentrationsSignificant decreaseInitial control periodDietary fiberMetabolic kitchenFollicular phaseMenstrual cycleFree estradiolAmount of fatEstrogen concentrationsHigh fiberDietary conditionsControl periodEstradiolIndependent effectsWomenAndrostenedioneFatHormone