2016
Effectiveness of Albendazole for Hookworm Varies Widely by Community and Correlates with Nutritional Factors: A Cross-Sectional Study of School-Age Children in Ghana.
Humphries D, Nguyen S, Kumar S, Quagraine JE, Otchere J, Harrison LM, Wilson M, Cappello M. Effectiveness of Albendazole for Hookworm Varies Widely by Community and Correlates with Nutritional Factors: A Cross-Sectional Study of School-Age Children in Ghana. American Journal Of Tropical Medicine And Hygiene 2016, 96: 347-354. PMID: 27895280, PMCID: PMC5303035, DOI: 10.4269/ajtmh.16-0682.Peer-Reviewed Original ResearchConceptsEgg reduction rateCross-sectional studyMass drug administrationSchool-aged childrenEffectiveness of albendazoleCure rateDrug AdministrationMid-upper arm circumferenceSoil-transmitted helminth infectionsHost factorsNutritional factorsSingle-dose albendazoleOverall cure rateBlood hemoglobin levelsKintampo North MunicipalitySignificant community-level variationIndividual host factorsWorld Health OrganizationCommon STHHemoglobin levelsArm circumferenceHookworm infectionHelminth infectionsDeworming programsHookworm prevalence
2012
The promise and pitfalls of mass drug administration to control intestinal helminth infections
Humphries D, Nguyen S, Boakye D, Wilson M, Cappello M. The promise and pitfalls of mass drug administration to control intestinal helminth infections. Current Opinion In Infectious Diseases 2012, 25: 584-589. PMID: 22903231, DOI: 10.1097/qco.0b013e328357e4cf.Peer-Reviewed Original ResearchConceptsMass drug administrationIntestinal helminth infectionsHelminth infectionsDrug AdministrationSoil-transmitted nematode infectionsIntensity of schistosomiasisHigh-risk groupResource-limited settingsLong-term controlSignificant morbidityPregnant womenLong-term benefitsNew drug developmentIntensity of infectionIntestinal helminthsEndemic areasConsistent benefitInfectionChemotherapeutic interventionCertain populationsDrug developmentBenzimidazole anthelminthicsIntensive monitoringPrevalenceAdministration