2003
Genetic influence of CXCR6 chemokine receptor alleles on PCP-mediated AIDS progression among African Americans
Duggal P, An P, Beaty T, Strathdee S, Farzadegan H, Markham R, Johnson L, O'Brien S, Vlahov D, Winkler C. Genetic influence of CXCR6 chemokine receptor alleles on PCP-mediated AIDS progression among African Americans. Genes & Immunity 2003, 4: 245-250. PMID: 12761559, DOI: 10.1038/sj.gene.6363950.Peer-Reviewed Original ResearchConceptsPneumocystis carinii pneumoniaLate-stage HIV-1 infectionAfrican AmericansHIV-1 infectionMedian survival timeSIV infectionCarinii pneumoniaChemokine receptorsAIDS progressionPrimary coreceptorSurvival timeK polymorphismInitial infectionCXCR6Receptor allelesInfectionProgressionSingle nucleotide polymorphismsDeathK genotypesAIDSCoreceptorNucleotide polymorphismsGenetic influencesAllele frequencies
1994
Drug smoking, Pneumocystis carinii pneumonia, and immunosuppression increase risk of bacterial pneumonia in human immunodeficiency virus-seropositive injection drug users.
Caiaffa W, Vlahov D, Graham N, Astemborski J, Solomon L, Nelson K, Muñoz A. Drug smoking, Pneumocystis carinii pneumonia, and immunosuppression increase risk of bacterial pneumonia in human immunodeficiency virus-seropositive injection drug users. American Journal Of Respiratory And Critical Care Medicine 1994, 150: 1493-1498. PMID: 7952605, DOI: 10.1164/ajrccm.150.6.7952605.Peer-Reviewed Original ResearchMeSH KeywordsAdultAIDS-Related Opportunistic InfectionsCocaineCohort StudiesCrack CocaineFemaleHIV SeronegativityHIV SeropositivityHIV-1HumansImmunocompromised HostIncidenceMaleMarijuana SmokingOdds RatioPneumoniaPneumonia, PneumocystisRisk FactorsSmokingSubstance Abuse, IntravenousSubstance-Related DisordersConceptsInjection drug usersPneumocystis carinii pneumoniaHIV-seropositive injection drug usersBacterial pneumoniaOdds ratioCarinii pneumoniaCigarette smokingFirst episodeDrug usersIllicit drugsSeropositive injection drug usersCD4 lymphocyte countHIV-seronegative subjectsMedical record reviewHuman immunodeficiency virusCells/Conditional logistic regressionSeronegative subjectsCohort studyLymphocyte countRecord reviewImmunodeficiency virusControl subjectsRisk factorsUnivariate analysis