2020
Impact of Gut Bacteria on the Infection and Transmission of Pathogenic Arboviruses by Biting Midges and Mosquitoes
Möhlmann TWR, Vogels CBF, Göertz GP, Pijlman GP, ter Braak CJF, te Beest DE, Hendriks M, Nijhuis EH, Warris S, Drolet BS, van Overbeek L, Koenraadt CJM. Impact of Gut Bacteria on the Infection and Transmission of Pathogenic Arboviruses by Biting Midges and Mosquitoes. Microbial Ecology 2020, 80: 703-717. PMID: 32462391, PMCID: PMC7476999, DOI: 10.1007/s00248-020-01517-6.Peer-Reviewed Original ResearchConceptsAntibiotic treatmentGut bacteriaChikungunya virusInfection ratePathogenic arbovirusesInfectious blood mealAegypti mosquitoesGut bacterial communitiesResident gut bacteriaGut bacterial compositionSchmallenberg virusAedes aegypti mosquitoesArbovirus infectionViral pathogensVirusTreatmentBlood mealInfectionMidgut bacteriaArbovirus transmissionHealth of animalsMosquitoesArbovirusesZikaBacterial composition
2018
Vector competence of biting midges and mosquitoes for Shuni virus
Möhlmann TWR, Oymans J, Schreur P, Koenraadt CJM, Kortekaas J, Vogels CBF. Vector competence of biting midges and mosquitoes for Shuni virus. PLOS Neglected Tropical Diseases 2018, 12: e0006993. PMID: 30532189, PMCID: PMC6285265, DOI: 10.1371/journal.pntd.0006993.Peer-Reviewed Original ResearchConceptsShuni virusInfection rateInfectious blood mealEvidence of transmissionHigher infection rateFebrile childrenCongenital malformationsNeurological diseasesPotential transmissionPotential involvementHigh pathogenicityZoonotic potentialSimbu serogroupBlood mealVector competenceVirusMosquitoesRiskBroad tropismArthropod vectorsAedes aegyptiAnimalsCulex pipiens pipiensFurther researchFuture epizootics
2017
Transmission of Rift Valley fever virus from European-breed lambs to Culex pipiens mosquitoes
Vloet RPM, Vogels CBF, Koenraadt CJM, Pijlman GP, Eiden M, Gonzales JL, van Keulen LJM, Schreur P, Kortekaas J. Transmission of Rift Valley fever virus from European-breed lambs to Culex pipiens mosquitoes. PLOS Neglected Tropical Diseases 2017, 11: e0006145. PMID: 29281642, PMCID: PMC5760105, DOI: 10.1371/journal.pntd.0006145.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCulexDisease SusceptibilityFemaleInsect VectorsRift Valley FeverRift Valley fever virusSheepSheep DiseasesConceptsRift Valley fever virusWild-type Rift Valley fever virusVector competenceNatural target speciesTarget cellsFever virusLaboratory-reared mosquitoesSkin samplesClone 13 strainPipiens mosquitoesPeak viremiaViremic periodVector competence experimentsTransmission of RVFVLocal mosquitoesInfected animalsClone 13Artificial blood feedingArtificial feeding experimentsGenus PhlebovirusSusceptible ruminantsVirusBlood feedingField-collected eggsCompetent vectorsVirus interferes with host-seeking behaviour of mosquito
Vogels CBF, Fros JJ, Pijlman GP, van Loon JJA, Gort G, Koenraadt CJM. Virus interferes with host-seeking behaviour of mosquito. Journal Of Experimental Biology 2017, 220: 3598-3603. PMID: 28978641, DOI: 10.1242/jeb.164186.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBirdsCulexFemaleHost-Seeking BehaviorInsect VectorsOlfactometrySensillaWest Nile virusVector competence of northern and southern European Culex pipiens pipiens mosquitoes for West Nile virus across a gradient of temperatures
Vogels CBF, Göertz GP, Pijlman GP, Koenraadt CJM. Vector competence of northern and southern European Culex pipiens pipiens mosquitoes for West Nile virus across a gradient of temperatures. Medical And Veterinary Entomology 2017, 31: 358-364. PMID: 28752627, DOI: 10.1111/mve.12251.Peer-Reviewed Original ResearchMosquito co-infection with Zika and chikungunya virus allows simultaneous transmission without affecting vector competence of Aedes aegypti
Göertz GP, Vogels CBF, Geertsema C, Koenraadt CJM, Pijlman GP. Mosquito co-infection with Zika and chikungunya virus allows simultaneous transmission without affecting vector competence of Aedes aegypti. PLOS Neglected Tropical Diseases 2017, 11: e0005654. PMID: 28570693, PMCID: PMC5469501, DOI: 10.1371/journal.pntd.0005654.Peer-Reviewed Original ResearchConceptsChikungunya virusZika virusAegypti mosquitoesIntrathoracic injectionPresence of ZIKVVector competenceInfectious blood mealSerious health burdenDual-color immunofluorescenceBlood mealMultiple mosquito bitesArthropod-borne virusZIKV productionSalivary gland barrierCase reportAedes aegypti mosquitoesHealth burdenOral exposureMosquito bitesViral titersPositive mosquitoesMosquito cellsBiteProfound barrierVirus
2016
Noncoding Subgenomic Flavivirus RNA Is Processed by the Mosquito RNA Interference Machinery and Determines West Nile Virus Transmission by Culex pipiens Mosquitoes
Göertz GP, Fros JJ, Miesen P, Vogels CB, van der Bent ML, Geertsema C, Koenraadt CJ, van Rij RP, van Oers MM, Pijlman GP. Noncoding Subgenomic Flavivirus RNA Is Processed by the Mosquito RNA Interference Machinery and Determines West Nile Virus Transmission by Culex pipiens Mosquitoes. Journal Of Virology 2016, 90: 10145-10159. PMID: 27581979, PMCID: PMC5105652, DOI: 10.1128/jvi.00930-16.Peer-Reviewed Original ResearchConceptsSubgenomic flavivirus RNARNA interference machineryCulex pipiens mosquitoesWest Nile virusInterference machinerySfRNA productionPipiens mosquitoesBiological functionsUntranslated regionNile virusPivotal biological functionsIntrathoracic injectionWild-type WNVRNA deep sequencingKey biological functionsBlood mealFlavivirus RNAMosquito cell linesFlavivirus West Nile virusViral genomic RNAMosquito midgut barrierMutant West Nile virusTick-borne flavivirusesWNV-infected mosquitoesMammalian cells
2015
Winter Activity and Aboveground Hybridization Between the Two Biotypes of the West Nile Virus Vector Culex pipiens
Vogels CB, van de Peppel LJ, van Vliet AJ, Westenberg M, Ibañez-Justicia A, Stroo A, Buijs JA, Visser TM, Koenraadt CJ. Winter Activity and Aboveground Hybridization Between the Two Biotypes of the West Nile Virus Vector Culex pipiens. Vector-Borne And Zoonotic Diseases 2015, 15: 619-626. PMID: 26394124, DOI: 10.1089/vbz.2015.1820.Peer-Reviewed Original Research
2014
Fitness consequences of larval exposure to Beauveria bassiana on adults of the malaria vector Anopheles stephensi
Vogels CB, Bukhari T, Koenraadt CJ. Fitness consequences of larval exposure to Beauveria bassiana on adults of the malaria vector Anopheles stephensi. Journal Of Invertebrate Pathology 2014, 119: 19-24. PMID: 24694552, DOI: 10.1016/j.jip.2014.03.003.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnophelesBeauveriaFemaleGenetic FitnessInsect VectorsLarvaMalariaMaleMosquito ControlPest Control, BiologicalConceptsAdult stageLarval stagesB. bassianaMalaria mosquitoesLarval exposureBeauveria bassianaSex ratioEntomopathogenic fungus Beauveria bassianaFungus Beauveria bassianaNon-exposed femalesMalaria vector AnophelesFitness consequencesReproductive successBiological controlEntomopathogenic fungiLarvalEqual survivalVector AnophelesBassianaLarval treatmentFungiFitnessAnopheles stephensi femalesLarvaeMosquitoes