1988
Production of growth factors related to fibroblast growth factor and platelet-derived growth factor by human embryonal carcinoma cells
Tiesman J, Meyer A, Hines R, Rizzino A. Production of growth factors related to fibroblast growth factor and platelet-derived growth factor by human embryonal carcinoma cells. In Vitro Cellular & Developmental Biology 1988, 24: 1209-1216. PMID: 3209587, DOI: 10.1007/bf02624192.Peer-Reviewed Original ResearchConceptsPlatelet-derived growth factorGrowth factorSK-Hep-1 cellsEC cellsMouse EC cellsCarcinoma cellsHuman EC cell linesNT2/D1Basic fibroblast growth factorGrowth factor productionHeparin-binding growth factorsEmbryonal carcinoma cellsEC cell linesPDGF A-chainFibroblast growth factorHuman embryonal carcinoma cellsHuman EC cellsMouse embryonal carcinoma cellsFactor productionFGFbCell linesCDNA probeSimilar salt concentrationsCellsCurrent studyInduction of cytochrome P-450IA1 gene expression in human breast tumour cell lines
Pasanen M, Stacey S, Lykkesfeldt A, Briand P, Hines R, Autrup H. Induction of cytochrome P-450IA1 gene expression in human breast tumour cell lines. Chemico-Biological Interactions 1988, 66: 223-232. PMID: 2456161, DOI: 10.1016/0009-2797(88)90073-7.Peer-Reviewed Original ResearchConceptsBreast tumor cell linesHuman breast tumor cell linesTumor cell linesTCDD treatmentCell linesDifferent breast tumor cell linesConcentrations of TCDDZR-75BT-20Cytochrome P-450IA1NM TCDDCAMA-1Basal expression levelsControl cellsExpression levelsMCF-7Northern blot analysisBlot analysisTCDDTreatmentTotal RNAP-450IA1TCDD inductionDiol metabolitesInduction
1987
Structural details of the human cytochrome P-450c gene
Iversen P, Heiger W, Bresnick E, Hines R. Structural details of the human cytochrome P-450c gene. Archives Of Biochemistry And Biophysics 1987, 256: 397-401. PMID: 3606130, DOI: 10.1016/0003-9861(87)90460-7.Peer-Reviewed Original ResearchAflatoxin B1-4-hydroxylase is associated with cytochrome P3-450 in C57BL6 mouse liver
Koser P, Faletto M, Bansal S, Caballes L, Bresnick E, Hines R, Gurtoo H. Aflatoxin B1-4-hydroxylase is associated with cytochrome P3-450 in C57BL6 mouse liver. Biochemical And Biophysical Research Communications 1987, 142: 872-878. PMID: 3103616, DOI: 10.1016/0006-291x(87)91494-x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAroclorsAryl Hydrocarbon HydroxylasesBenzoflavonesBeta-NaphthoflavoneChlorodiphenyl (54% Chlorine)Cytochrome P-450 Enzyme SystemDNAEnzyme InductionFemaleLiverMethylcholanthreneMiceMice, Inbred C57BLMixed Function OxygenasesNucleic Acid HybridizationPolychlorinated BiphenylsRNA, Messenger
1985
3-Methylcholanthrene-induced expression of the cytochrome P-450c gene
Foldes R, Hines R, Ho K, Shen M, Nagel K, Bresnick E. 3-Methylcholanthrene-induced expression of the cytochrome P-450c gene. Archives Of Biochemistry And Biophysics 1985, 239: 137-146. PMID: 4004253, DOI: 10.1016/0003-9861(85)90820-3.Peer-Reviewed Original ResearchConceptsNuclear RNA speciesCytochrome P-450c mRNARNA speciesCytochrome P-450c geneP-450c geneClone 46Nuclear transcription systemNuclear RNA precursorsNuclear RNA transportRat serum albumin geneDot hybridization experimentsSerum albumin geneNorthern blot analysisTranscriptional controlRNA transportRNA precursorsNuclear RNARegulation of inductionHybridization experimentsTranscription systemM13 subclonesAlbumin geneCytochrome P-450cRNA inductionSpeciesGene structure and nucleotide sequence for rat cytochrome P-450c
Hines R, Levy J, Conrad R, Iversen P, Shen M, Renli A, Bresnick E. Gene structure and nucleotide sequence for rat cytochrome P-450c. Archives Of Biochemistry And Biophysics 1985, 237: 465-476. PMID: 3838427, DOI: 10.1016/0003-9861(85)90300-5.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceChemical PhenomenaChemistryCloning, MolecularCytochrome P-450 Enzyme SystemDNAGenesHumansNucleic Acid HybridizationRatsConceptsRat cytochrome P-450cRegulatory sequencesCDNA sequenceEntire geneSecond genomic cloneCommon ancestral geneGenomic blot analysisComplete cDNA sequenceIntron/exon junctionsPotential regulatory sequencesCytochrome P-450c mRNACytochrome P-450c genePartial cDNA cloneRat genomic libraryAmino acid sequenceCross-hybridization studiesGross structural differencesA fragmentGT/AGExon 2P-450c geneAncestral geneGene structureGenomic clonesCytochrome P3-450
1983
Molecular induction by phenobarbital of a rat hepatic form of cytochrome P-450: Expression of a 4-kilobase messenger RNA
Omiecinski C, Hines R, Foldes R, Levy J, Bresnick E. Molecular induction by phenobarbital of a rat hepatic form of cytochrome P-450: Expression of a 4-kilobase messenger RNA. Archives Of Biochemistry And Biophysics 1983, 227: 478-493. PMID: 6141764, DOI: 10.1016/0003-9861(83)90478-2.Peer-Reviewed Original Research
1981
The molecular cloning of cytochrome P-450c information
Bresnick E, Levy J, Hines R, Levin W, Thomas P. The molecular cloning of cytochrome P-450c information. Archives Of Biochemistry And Biophysics 1981, 212: 501-507. PMID: 7034652, DOI: 10.1016/0003-9861(81)90393-3.Peer-Reviewed Original Research