Ronald Hines
Professor Adjunct of Epidemiology (Environmental Health)Cards
About
Research
Publications
2020
Physiologically Based Pharmacokinetic Modeling in Risk Assessment: Case Study With Pyrethroids
Mallick P, Song G, Efremenko A, Pendse S, Creek M, Osimitz T, Hines R, Hinderliter P, Clewell H, Lake B, Yoon M, Moreau M. Physiologically Based Pharmacokinetic Modeling in Risk Assessment: Case Study With Pyrethroids. Toxicological Sciences 2020, 176: 460-469. PMID: 32421774, PMCID: PMC7416317, DOI: 10.1093/toxsci/kfaa070.Peer-Reviewed Original ResearchBringing Big Data to Bear in Environmental Public Health: Challenges and Recommendations
Comess S, Akbay A, Vasiliou M, Hines RN, Joppa L, Vasiliou V. Bringing Big Data to Bear in Environmental Public Health: Challenges and Recommendations. Frontiers In Artificial Intelligence 2020, 3: 31. PMID: 33184612, PMCID: PMC7654840, DOI: 10.3389/frai.2020.00031.Peer-Reviewed Original Research
2019
Development and Application of a Life-Stage Physiologically Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in Humans
Mallick P, Moreau M, Song G, Efremenko A, Pendse S, Creek M, Osimitz T, Hines R, Hinderliter P, Clewell H, Lake B, Yoon M. Development and Application of a Life-Stage Physiologically Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in Humans. Toxicological Sciences 2019, 173: 86-99. PMID: 31593217, PMCID: PMC6944222, DOI: 10.1093/toxsci/kfz211.Peer-Reviewed Original ResearchA Time-Embedding Network Models the Ontogeny of 23 Hepatic Drug Metabolizing Enzymes
Matlock M, Tambe A, Elliott-Higgins J, Hines R, Miller G, Swamidass S. A Time-Embedding Network Models the Ontogeny of 23 Hepatic Drug Metabolizing Enzymes. Chemical Research In Toxicology 2019, 32: 1707-1721. PMID: 31304741, PMCID: PMC6933754, DOI: 10.1021/acs.chemrestox.9b00223.Peer-Reviewed Original ResearchDevelopmental Expression of the Cytosolic Sulfotransferases in Human Liver
Dubaisi S, Caruso J, Gaedigk R, Vyhlidal C, Smith P, Hines R, Kocarek T, Runge-Morris M. Developmental Expression of the Cytosolic Sulfotransferases in Human Liver. Drug Metabolism And Disposition 2019, 47: 592-600. PMID: 30885913, PMCID: PMC6505379, DOI: 10.1124/dmd.119.086363.Peer-Reviewed Original ResearchA Chemical Category-Based Prioritization Approach for Selecting 75 Per- and Polyfluoroalkyl Substances (PFAS) for Tiered Toxicity and Toxicokinetic Testing
Patlewicz G, Richard A, Williams A, Grulke C, Sams R, Lambert J, Noyes P, DeVito M, Hines R, Strynar M, Guiseppi-Elie A, Thomas R. A Chemical Category-Based Prioritization Approach for Selecting 75 Per- and Polyfluoroalkyl Substances (PFAS) for Tiered Toxicity and Toxicokinetic Testing. Environmental Health Perspectives 2019, 127: 014501. PMID: 30632786, PMCID: PMC6378680, DOI: 10.1289/ehp4555.Peer-Reviewed Original Research
2018
The Impact of Scaling Factor Variability on Risk-Relevant Pharmacokinetic Outcomes in Children: A Case Study Using Bromodichloromethane (BDCM)
Kenyon E, Lipscomb J, Pegram R, George B, Hines R. The Impact of Scaling Factor Variability on Risk-Relevant Pharmacokinetic Outcomes in Children: A Case Study Using Bromodichloromethane (BDCM). Toxicological Sciences 2018, 167: 347-359. PMID: 30252107, PMCID: PMC10448349, DOI: 10.1093/toxsci/kfy236.Peer-Reviewed Original Research
2017
Application of epigenetic data in human health risk assessment
Cote I, McCullough S, Hines R, Vandenberg J. Application of epigenetic data in human health risk assessment. Current Opinion In Toxicology 2017, 6: 71-78. PMID: 29333520, PMCID: PMC5759783, DOI: 10.1016/j.cotox.2017.09.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsDetermination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages
Song G, Sun X, Hines R, McCarver D, Lake B, Osimitz T, Creek M, Clewell H, Yoon M. Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages. Drug Metabolism And Disposition 2017, 45: 468-475. PMID: 28228413, DOI: 10.1124/dmd.116.074583.Peer-Reviewed Original Research
2016
FutureTox III: Bridges for Translation
Juberg D, Knudsen T, Sander M, Beck N, Faustman E, Mendrick D, Fowle J, Hartung T, Tice R, Lemazurier E, Becker R, Fitzpatrick S, Daston G, Harrill A, Hines R, Keller D, Lipscomb J, Watson D, Bahadori T, Crofton K. FutureTox III: Bridges for Translation. Toxicological Sciences 2016, 155: 22-31. PMID: 27780885, PMCID: PMC6080854, DOI: 10.1093/toxsci/kfw194.Peer-Reviewed Original Research