A Tiered Approach to Life Stages Testing for Agricultural Chemical Safety Assessment
Cooper R, Lamb J, Barlow S, Bentley K, Brady A, Doerrer N, Eisenbrandt D, Fenner-Crisp P, Hines R, Irvine L, Kimmel C, Koeter H, Li A, Makris S, Sheets L, Speijers G, Whitby K. A Tiered Approach to Life Stages Testing for Agricultural Chemical Safety Assessment. Critical Reviews In Toxicology 2006, 36: 69-98. PMID: 16708695, DOI: 10.1080/10408440500541367.Peer-Reviewed Original ResearchConceptsAgricultural Chemical Safety Assessment (ACSA) Technical CommitteeRat reproductionInterpretation of studiesCompound potentialsGuideline studiesAdverse effectsSeverity of effectsHuman exposure potentialEnvironmental Sciences InstituteYoung animalsADME dataILSI HealthTiered approachEndpointExposure durationTask ForceExtent of testingTesting strategiesExposure potentialToxicity informationToxicological endpointsAnimalsChemical safety assessment