2008
CYP3A4 regulation by DBP and E4BP4 transcription factors
Maas K, Le M, Hines R. CYP3A4 regulation by DBP and E4BP4 transcription factors. The FASEB Journal 2008, 22: 921.7-921.7. DOI: 10.1096/fasebj.22.1_supplement.921.7.Peer-Reviewed Original ResearchD-element binding proteinDose-dependent mannerCYP3A4 promoter activityPromoter activityLuciferase expressionCYP3A4 regulationPostnatal liverLuciferase reporterProtein 4Luciferase activityHepG2 cellsE4BP4Binding proteinDevelopmental expression patternsResponsive elementExpression patternsHigh affinityProximal promoterTranscription factorsExpressionActivity
2007
Regulation of CYP3A4 Expression by PAR Transcription Factors
Mantei K, Le M, Klick D, Vyhlidal C, Hines R. Regulation of CYP3A4 Expression by PAR Transcription Factors. The FASEB Journal 2007, 21: a1183-a1183. DOI: 10.1096/fasebj.21.6.a1183-a.Peer-Reviewed Original ResearchD-element binding proteinCYP3A4 expressionHepatic leukemia factorCYP3A4 promoter activityAdult human liverAbundant cytochrome P450CYP3A4 promoterHuman liverPostnatal liverProtein 4DBP expressionPAR familyEmbryonic factorsHepG2 cellsTranscription factorsCytochrome P450LiverFunctional significanceCo-transfection experimentsBinding proteinPromoter activityExpressionReporter constructsFactorsFactor family