Variation in Induction of Human Placental CYP2E1: Possible Role in Susceptibility to Fetal Alcohol Syndrome?
Rasheed A, Hines R, McCarver-May D. Variation in Induction of Human Placental CYP2E1: Possible Role in Susceptibility to Fetal Alcohol Syndrome? Toxicology And Applied Pharmacology 1997, 144: 396-400. PMID: 9194424, DOI: 10.1006/taap.1997.8152.Peer-Reviewed Original ResearchConceptsFetal alcohol syndromeAlcohol syndromeIntersubject variationHeavy drinking womenSmall birth weightAbsolute alcohol intakeWestern blot analysisBirth lengthAlcohol intakeDrinking womenHepatic CYP2E1Birth weightTerm placentaHeavy drinkersAlcohol metabolismCYP2E1Placental microsomesHuman placentaHeavy drinkingPlacentaTime pointsPotential mechanismsEnvironmental agentsWomenPregnancy