Novel Hispanic American CYP2C9 Genetic Variants and Assessment of Their Impact on Gene Expression
Kramer M, Rettie A, Rieder M, Hines R. Novel Hispanic American CYP2C9 Genetic Variants and Assessment of Their Impact on Gene Expression. The FASEB Journal 2007, 21: a415-a415. DOI: 10.1096/fasebj.21.5.a415.Peer-Reviewed Original ResearchSingle nucleotide polymorphismsPromoter activityGenetic variantsSite-directed mutagenesisConstitutive promoter activityInducible promoter activityDNA samplesMultiplex single-base extensionInduced promoter activityLuciferase reporter plasmidRegulatory sequencesTransient expressionRegulatory polymorphismsGene expressionSNP frequenciesFrequency of variantsReporter plasmidDNA sequencingSingle base extensionHaplotype variantsNucleotide polymorphismsReference haplotypesHepG2 cellsDiscovery resourcesDifferent populations