2014
Current drug use and lack of HIV virologic suppression: point-of-care urine drug screen versus self-report
Qian HZ, Mitchell VJ, Bebawy S, Cassell H, Perez G, McGowan CC, Sterling TR, Vermund SH, D’Aquila R, Hulgan T. Current drug use and lack of HIV virologic suppression: point-of-care urine drug screen versus self-report. BMC Infectious Diseases 2014, 14: 508. PMID: 25234368, PMCID: PMC4175271, DOI: 10.1186/1471-2334-14-508.Peer-Reviewed Original ResearchConceptsUrine drug screensCurrent drug usePositive urine drug screenComputer Assisted Self-InterviewVirologic suppressionDrug useAntiretroviral therapyDrug screensNegative urine drug screensHigher CD4 countsHIV disease progressionRoutine clinic visitsHIV virologic suppressionCross-sectional studyLower self-reported ratesSelf-reported ratesCD4 countClinic visitsPrognostic informationDisease progressionCaucasian raceART usersLower likelihoodResultsAbout halfSelf interview
2009
Predictors of Suboptimal Virologic Response to Highly Active Antiretroviral Therapy Among Human Immunodeficiency Virus–Infected Adolescents: Analyses of the Reaching for Excellence in Adolescent Care and Health (REACH) Project
Ding H, Wilson CM, Modjarrad K, McGwin G, Tang J, Vermund SH. Predictors of Suboptimal Virologic Response to Highly Active Antiretroviral Therapy Among Human Immunodeficiency Virus–Infected Adolescents: Analyses of the Reaching for Excellence in Adolescent Care and Health (REACH) Project. JAMA Pediatrics 2009, 163: 1100-1105. PMID: 19996046, PMCID: PMC3739292, DOI: 10.1001/archpediatrics.2009.204.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAntiretroviral Therapy, Highly ActiveCD4 Lymphocyte CountChi-Square DistributionFemaleHIV InfectionsHumansInterviews as TopicLogistic ModelsMalePatient CompliancePredictive Value of TestsPrevalenceProspective StudiesStatistics, NonparametricTreatment OutcomeUnited StatesViral LoadYoung AdultConceptsHuman immunodeficiency virus-infected adolescentsSuboptimal virologic responsePoor virologic responseVirologic responseActive antiretroviral therapyAntiretroviral therapyVirologic suppressionMultivariable logistic regression modelDual antiretroviral therapyInitiation of HAARTSuboptimal antiretroviral therapyAge-specific interventionsAcademic medical centerLogistic regression modelsCohort studyLymphocyte countViral loadEcho findingsAdequate adherenceTherapeutic failureBiopsychosocial predictorsHAARTMedical CenterAdolescent careConsecutive visitsAdult combination antiretroviral therapy in sub-Saharan Africa: lessons from Botswana and future challenges
Wester CW, Bussmann H, Koethe J, Moffat C, Vermund S, Essex M, Marlink RG. Adult combination antiretroviral therapy in sub-Saharan Africa: lessons from Botswana and future challenges. HIV Therapy 2009, 3: 501-526. PMID: 20161344, PMCID: PMC2774911, DOI: 10.2217/hiv.09.35.Peer-Reviewed Original ResearchCombination antiretroviral therapyAntiretroviral therapyUse of cARTFirst-line combination antiretroviral therapyHIV-1-infected adultsPrimary HIV-1 infectionMonths of treatmentHIV-1 infectionResource-rich settingsHigh mortality rateImmunologic recoveryVirologic suppressionHIV infectionHealthcare utilizationSaharan AfricaAdherence ratesLifelong monitoringPROGRESS trialTreatment outcomesMortality rateCART programClinical servicesImpressive declineTherapyInfection