2019
Syphilis associated with recreational drug use, depression and high-risk sexual behaviour in men who have sex with men: a case–control study in China
Wu H, Xiu C, Fu X, Li M, Wang Z, Li X, Wu J, Vermund SH, Hu Y. Syphilis associated with recreational drug use, depression and high-risk sexual behaviour in men who have sex with men: a case–control study in China. Sexually Transmitted Infections 2019, 95: 267-272. PMID: 30842346, PMCID: PMC11093516, DOI: 10.1136/sextrans-2018-053878.Peer-Reviewed Original ResearchConceptsRecreational drug useHigh-risk sexual behaviorCase-control studyDrug useSyphilis infectionToluidine red unheated serum testUnmatched case-control studyRed unheated serum testMultivariable logistic regressionPotential risk factorsMultiple drug useSexual behaviorPrior STIFrequent methamphetamine useSyphilis prevalenceSyphilis testingRisk factorsSerum testHealth workersDepression scoresSelf-administrated questionnaireRecreational drugsLogistic regressionSyphilisMethamphetamine use
2018
Risk Prediction Score for HIV Infection: Development and Internal Validation with Cross-Sectional Data from Men Who Have Sex with Men in China
Yin L, Zhao Y, Peratikos MB, Song L, Zhang X, Xin R, Sun Z, Xu Y, Zhang L, Hu Y, Hao C, Ruan Y, Shao Y, Vermund SH, Qian HZ. Risk Prediction Score for HIV Infection: Development and Internal Validation with Cross-Sectional Data from Men Who Have Sex with Men in China. AIDS And Behavior 2018, 22: 2267-2276. PMID: 29786768, PMCID: PMC7024582, DOI: 10.1007/s10461-018-2129-y.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAlcohol DrinkingChinaCondomsCross-Sectional StudiesHIV InfectionsHomosexuality, MaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisPrevalenceRisk AssessmentRisk FactorsRisk-TakingSafe SexSexual and Gender MinoritiesSexual BehaviorSexual PartnersSurveys and QuestionnairesSyphilisUnsafe SexYoung AdultConceptsHIV infectionRisk scoreHuman immunodeficiency virus (HIV) riskMultivariable logistic regression modelingBootstrap-corrected C-indexMultiple male sexual partnersValid risk scoreVaccine clinical trialsHigh-risk MSMHigh-risk personsRisk prediction scoreReceptive anal intercourseReceptive anal sexInconsistent condom useMale sexual partnersHIV prevention programmingLogistic regression modelingDrug/alcohol addictionHIV acquisitionRisk reduction programsSyphilis infectionHIV prevalenceClinical trialsC-indexIllegal drug use
2017
HIV testing and sexual risks among migrant men who have sex with men: findings from a large cross-sectional study in Beijing, China
Liu Y, Vermund SH, Ruan Y, Liu H, Zhang C, Yin L, Shao Y, Qian HZ. HIV testing and sexual risks among migrant men who have sex with men: findings from a large cross-sectional study in Beijing, China. AIDS Care 2017, 30: 86-94. PMID: 28944685, PMCID: PMC6088860, DOI: 10.1080/09540121.2017.1381331.Peer-Reviewed Original ResearchConceptsLifetime male sexual partnersCondomless receptive anal sexHIV testingMigrant MSMHIV perceptionAnal sexHIV/syphilis infectionOlder ageLarge cross-sectional studyHIV/STI riskLikelihood of syphilisHIV/syphilisInsertive anal sexReceptive anal sexCross-sectional studyMale sexual partnersSyphilis infectionHIV transmissionLocal MSMSTI riskChinese MSMLower oddsEpidemiological studiesSexual partnersRisk profile
2016
Alcohol misuse, risky sexual behaviors, and HIV or syphilis infections among Chinese men who have sex with men
Liu Y, Ruan Y, Strauss SM, Yin L, Liu H, Amico KR, Zhang C, Shao Y, Qian HZ, Vermund SH. Alcohol misuse, risky sexual behaviors, and HIV or syphilis infections among Chinese men who have sex with men. Drug And Alcohol Dependence 2016, 168: 239-246. PMID: 27723554, PMCID: PMC5523945, DOI: 10.1016/j.drugalcdep.2016.09.020.Peer-Reviewed Original ResearchConceptsAlcohol Use Disorders Identification Test-ConsumptionSyphilis infectionBinge drinkersChinese menAlcohol misuseCondomless insertive anal intercourseHIV/syphilis infectionRecent alcohol misuseAlcohol risk reduction programCross-sectional studyInsertive anal intercourseAUDIT-C scoresCurrent alcohol dependenceInterviewer-administered surveyHigh-risk behaviorsRisk reduction programsRisky sexual behaviorMisuse MeasureHIV riskChinese MSMAnal intercourseHigh riskSyphilis riskBinge drinkingHazardous drinkersSexual Behaviors Linked to Drug and Alcohol Use Among Men Who Have Sex With Men in China
Zhang C, Qian HZ, Yin L, Liu Y, Strauss SM, Ruan Y, Shao Y, Lu H, Vermund SH. Sexual Behaviors Linked to Drug and Alcohol Use Among Men Who Have Sex With Men in China. Substance Use & Misuse 2016, 51: 1821-1830. PMID: 27608264, PMCID: PMC5423713, DOI: 10.1080/10826084.2016.1197264.Peer-Reviewed Original ResearchConceptsAlcohol useHigher oddsAlcohol consumptionSexual behaviorDrug useHigh-risk sexual behaviorFemale partnersHistory of alcoholSexual risk behaviorsHigh-risk behaviorsEffects of drugsSelf-administered questionnaireSyphilis infectionHIV infectionSyphilis prevalenceMean ageSyphilis testingClinical trialsHIV epidemicHIV interventionsBlood samplesHIVHan ethnicityRisk behaviorsMSM
2014
A-101 New Evidence that Circumcision Might Protect MSM from HIV
Vermund S, Qian H, Ruan Y, Shao Y, Liu Y, Milam D, Spiegel H, Li D, Yin L. A-101 New Evidence that Circumcision Might Protect MSM from HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2014, 67: 37. DOI: 10.1097/01.qai.0000456053.93927.60.Peer-Reviewed Original ResearchInsertive anal sexAnal sexUncircumcised menCircumcision statusMale circumcisionMultivariate logistic regression analysisOdds of HIVUnknown HIV statusHIV prevention strategiesCross-sectional studyInsertive anal intercourseLogistic regression analysisAnal sex rolesAdjusted riskHIV clinicSyphilis infectionHIV statusClinical trialsCircumcision ratesGenital examinationAnal intercourseLower oddsGenital examHIVPrevention strategiesHIV and syphilis prevalence trends among men who have sex with men in Guangxi, China: yearly cross-sectional surveys, 2008–2012
Wang X, Lan G, Shen Z, Vermund SH, Zhu Q, Chen Y, Khoshnood K, Wu Z, Tang Z. HIV and syphilis prevalence trends among men who have sex with men in Guangxi, China: yearly cross-sectional surveys, 2008–2012. BMC Infectious Diseases 2014, 14: 367. PMID: 24993252, PMCID: PMC4091643, DOI: 10.1186/1471-2334-14-367.Peer-Reviewed Original ResearchConceptsYears of ageSyphilis prevalenceCross-sectional surveyCurrent syphilisHIV prevalencePrevalence trendsSexual intercourseIncident HIV casesAnnual cross-sectional surveyRisk factor dataSignificant predictorsRisk of HIVNational sentinel surveillanceYearly cross-sectional surveysHIV/AIDSSyphilis infectionHIV infectionHIV casesSentinel surveillanceRisk factorsBlood samplesHIVKey populationsMSMPrevalence
2013
Effectiveness of HIV Risk Reduction Interventions among Men who have Sex with Men in China: A Systematic Review and Meta-Analysis
Lu H, Liu Y, Dahiya K, Qian HZ, Fan W, Zhang L, Ma J, Ruan Y, Shao Y, Vermund SH, Yin L. Effectiveness of HIV Risk Reduction Interventions among Men who have Sex with Men in China: A Systematic Review and Meta-Analysis. PLOS ONE 2013, 8: e72747. PMID: 24137497, PMCID: PMC3796948, DOI: 10.1371/journal.pone.0072747.Peer-Reviewed Original ResearchConceptsRisk reduction interventionsHIV risk reduction interventionsPrevalence of HIVRandomized clinical trialsStandardized mean differenceReduction interventionsIntervention studiesSexual partnersChinese MSMSystematic reviewHIV/AIDS-related knowledgeCross-sectional intervention studyEffect sizeRegular sexual partnersPost-intervention studyMale sexual partnersConsistent condom useRandom-effects modelPost-intervention assessmentCasual sexual partnersSyphilis infectionHIV testingStudy armsHIV knowledgeClinical trialsSex with Women Among Men Who Have Sex with Men in China: Prevalence and Sexual Practices
Tao J, Ruan Y, Yin L, Vermund SH, Shepherd BE, Shao Y, Qian HZ. Sex with Women Among Men Who Have Sex with Men in China: Prevalence and Sexual Practices. AIDS Patient Care And STDs 2013, 27: 524-528. PMID: 23931683, PMCID: PMC3760059, DOI: 10.1089/apc.2013.0161.Peer-Reviewed Original ResearchConceptsPotential bridge populationPrevalence of HIVSubgroup of menPrevention intervention programsHIV prevention intervention programsSyphilis infectionEligible MSMHIV transmissionAlcohol drinkingAnal sexOlder ageLower educationInsertive roleWomenIntervention programsSexMenBisexual behaviorHIVSignificant differencesStrongest predictorBisexual orientationSexual practicesBridge populationInfection
2012
Prevention, Detection, and Treatment of Coinfections: A Priority in Human Immunodeficiency Virus–Infected Persons to Reduce Viral Load and Consequent Disease Progression and Transmission : Comment on “Effect of Early Syphilis Infection on Plasma Viral Load and CD4 Cell Count in Human Immunodeficiency Virus–Infected Men”
Vermund SH. Prevention, Detection, and Treatment of Coinfections: A Priority in Human Immunodeficiency Virus–Infected Persons to Reduce Viral Load and Consequent Disease Progression and Transmission : Comment on “Effect of Early Syphilis Infection on Plasma Viral Load and CD4 Cell Count in Human Immunodeficiency Virus–Infected Men”. JAMA Internal Medicine 2012, 172: 1243-1244. PMID: 22824925, DOI: 10.1001/archinternmed.2012.3770.Peer-Reviewed Original ResearchPredictors of HIV and Syphilis among Men Who Have Sex with Men in a Chinese Metropolitan City: Comparison of Risks among Students and Non-Students
Zhang L, Ding X, Lu R, Feng L, Li X, Xiao Y, Ruan Y, Vermund SH, Shao Y, Qian HZ. Predictors of HIV and Syphilis among Men Who Have Sex with Men in a Chinese Metropolitan City: Comparison of Risks among Students and Non-Students. PLOS ONE 2012, 7: e37211. PMID: 22623994, PMCID: PMC3356386, DOI: 10.1371/journal.pone.0037211.Peer-Reviewed Original ResearchConceptsSyphilis infectionRisky sexual behaviorHIV prevalenceStudent MSMMultivariable logistic regression analysisSexual behaviorPredictors of HIVLow HIV prevalencePrevalence of syphilisRisk of HIVLogistic regression analysisRisk sexual behaviourLow HIVHIV infectionSyphilis prevalenceComparison of risksSyphilis testingAdjusted prevalenceHigh prevalenceHIV riskBlood specimensHIVMSM participantsMultivariate analysisSexual partners
2010
Prevalence and Correlates of HIV and Syphilis Infections Among Men Who Have Sex With Men in Seven Provinces in China With Historically Low HIV Prevalence
Xiao Y, Sun J, Li C, Lu F, Allen KL, Vermund SH, Jia Y. Prevalence and Correlates of HIV and Syphilis Infections Among Men Who Have Sex With Men in Seven Provinces in China With Historically Low HIV Prevalence. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2010, 53: s66-s73. PMID: 20104113, DOI: 10.1097/qai.0b013e3181c7db43.Peer-Reviewed Original ResearchConceptsLow HIV prevalenceSyphilis infectionInconsistent condom useHIV prevalenceMSM populationAnal sexCondom usePassive particle agglutination testOlder ageCorrelates of HIVLess educationBehavioral risk factorsRapid plasma reaginParticle agglutination testWestern blot confirmationDetection of TreponemaEnzyme-linked immunosorbentCross-sectional surveyHIV infectionRisk factorsBlood samplesMSM participantsHIVAgglutination testInfection
2009
Prevalence of HIV infection and predictors for syphilis infection among female sex workers in southern China.
Lu F, Jia Y, Sun X, Wang L, Liu W, Xiao Y, Zeng G, Li C, Liu J, Cassell H, Chen HT, Vermund SH. Prevalence of HIV infection and predictors for syphilis infection among female sex workers in southern China. The Southeast Asian Journal Of Tropical Medicine And Public Health 2009, 40: 263-72. PMID: 19323011, PMCID: PMC2745968.Peer-Reviewed Original ResearchConceptsFemale sex workersInconsistent condom useSyphilis infectionHIV infectionCondom usePast monthSex workersCross-sectional studyRegular sex partnersVenue-based methodsHalf of participantsEligible participantsRisk factorsSTD symptomsPrevalence ratesDrug usersSex partnersInfectionLess educationPrevalenceMinority ethnic groupsMonthsLiuzhou CityEthnic groupsNon-local residents
2008
Risk Factors for Syphilis and Prevalence of HIV, Hepatitis B and C among Men Who Have Sex with Men in Beijing, China: Implications for HIV Prevention
Ruan Y, Luo F, Jia Y, Li X, Li Q, Liang H, Zhang X, Li D, Shi W, Freeman JM, Vermund SH, Shao Y. Risk Factors for Syphilis and Prevalence of HIV, Hepatitis B and C among Men Who Have Sex with Men in Beijing, China: Implications for HIV Prevention. AIDS And Behavior 2008, 13: 663-670. PMID: 19082879, PMCID: PMC2747785, DOI: 10.1007/s10461-008-9503-0.Peer-Reviewed Original ResearchConceptsMale sex partnersSex partnersHepatitis BHIV prevalenceLifetime male sex partnersCasual male sex partnersPrevalence of HIVUnprotected anal intercourseAlcohol-related interventionsHepatitis CSyphilis infectionCondom promotionRisk factorsHIV preventionBeijing MSMMedian numberSTD controlDrank alcoholAnal intercourseRisk behaviorsPast monthAlcohol usePrevalencePrevention effortsSyphilisPredictors of HIV infection and prevalence for syphilis infection among injection drug users in China: Community-based surveys along major drug trafficking routes
Jia Y, Lu F, Zeng G, Sun X, Xiao Y, Lu L, Liu W, Ni M, Qu S, Li C, Liu J, Wu P, Vermund SH. Predictors of HIV infection and prevalence for syphilis infection among injection drug users in China: Community-based surveys along major drug trafficking routes. Harm Reduction Journal 2008, 5: 29. PMID: 18724872, PMCID: PMC2556669, DOI: 10.1186/1477-7517-5-29.Peer-Reviewed Original ResearchMajor drug trafficking routesIndependent risk factorInjection drug usersHIV transmission routesHIV infectionRisk factorsHIV seropositivityLonger durationDrug usersCommunity-based VCTFrequent drug injectionHIV preventive servicesDrug trafficking routesHigh-risk personsSexual behavior informationTransmission routesCommunity-based surveyPopulation-level interventionsSpread of HIVCommunity-level interventionsSyphilis seropositivitySyphilis infectionIndependent predictorsMultivariable analysisNeedle sharingPredictors of unprotected sex among men who have sex with men in Beijing, China.
Li X, Shi W, Li D, Ruan Y, Jia Y, Vermund SH, Zhang X, Wang C, Liu Y, Yu M, Xing H, Hong K, Shao Y. Predictors of unprotected sex among men who have sex with men in Beijing, China. The Southeast Asian Journal Of Tropical Medicine And Public Health 2008, 39: 99-108. PMID: 18567448, PMCID: PMC2730761.Peer-Reviewed Original ResearchConceptsUnprotected anal intercourseMale sex partnersSex partnersAnal intercourseMore male sex partnersMale partnersPrevalence of HIVReceptive anal intercourseCasual male partnersRegular male partnersCommunity-based surveyLow monthly incomeCasual sex partnersMale sex workersSyphilis infectionCondom promotionHIV epidemicUnprotected sexHIVSex workersPeer referralMenSexMonthly incomeInfection
1994
Sexually Transmitted Diseases, Sexual Behavior, and Cocaine Use in Inner-city Women
DeHovitz J, Kelly P, Feldman J, Sierra M, Clarke L, Bromberg J, Wan J, Vermund S, Landesman S. Sexually Transmitted Diseases, Sexual Behavior, and Cocaine Use in Inner-city Women. American Journal Of Epidemiology 1994, 140: 1125-1134. PMID: 7998594, DOI: 10.1093/oxfordjournals.aje.a117212.Peer-Reviewed Original ResearchConceptsInner-city womenDrug useCocaine useSTD/HIV prevention programsPresence of STDsRecent crack cocaine useHIV-positive womenInjection drug useCocaine usersHIV prevention programsDrug use historyForeign-born womenCrack cocaine useSyphilis infectionMedical historyHigh riskLaboratory confirmationSerologic analysisTransmitted DiseasesPrevention programsToxicologic analysisUrine samplesWomenCrack cocaineSexual behavior