2013
Can Combination Prevention Strategies Reduce HIV Transmission in Generalized Epidemic Settings in Africa? The HPTN 071 (PopART) Study Plan in South Africa and Zambia
Vermund SH, Fidler SJ, Ayles H, Beyers N, Hayes RJ. Can Combination Prevention Strategies Reduce HIV Transmission in Generalized Epidemic Settings in Africa? The HPTN 071 (PopART) Study Plan in South Africa and Zambia. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2013, 63: s221-s227. PMID: 23764639, PMCID: PMC3739051, DOI: 10.1097/qai.0b013e318299c3f4.Peer-Reviewed Original ResearchConceptsHIV Prevention Trials NetworkHPTN 071 (PopART) studyHPTN 071HIV incidenceHIV transmissionHome-based HIV testingVoluntary medical male circumcisionGeneralized epidemic settingsLinkage of HIVUniversal antiretroviral therapyChild HIV transmissionPrevention of motherHIV viral loadCommunity health workersMedical male circumcisionCommunity-randomized trialIntervention strategiesCombination prevention strategiesAntiretroviral therapyHIV acquisitionSeropositive personsTuberculosis servicesHIV testingViral loadTuberculosis transmission
2008
Impact of small reductions in plasma HIV RNA levels on the risk of heterosexual transmission and disease progression
Modjarrad K, Chamot E, Vermund SH. Impact of small reductions in plasma HIV RNA levels on the risk of heterosexual transmission and disease progression. AIDS 2008, 22: 2179-2185. PMID: 18832881, PMCID: PMC2661869, DOI: 10.1097/qad.0b013e328312c756.Peer-Reviewed Original ResearchConceptsRisk of progressionHeterosexual transmissionDisease progressionHIV RNALog10 incrementAntiretroviral therapyPlasma HIV RNA levelsGreater riskTreatment of coinfectionHIV RNA levelsHIV viral loadViral load changesHIV-1 RNARelative risk estimatesHIV loadAdjunctive careViral loadPlasma levelsHeterosexual contactWorld's HIVAnnual riskHIVAdult populationViral transmissionRisk estimates
2007
Influence of body mass index on pregnancy outcomes among HIV‐infected and HIV‐uninfected Zambian women
Banda Y, Chapman V, Goldenberg RL, H. B, Vermund SH, Stringer JS. Influence of body mass index on pregnancy outcomes among HIV‐infected and HIV‐uninfected Zambian women. Tropical Medicine And International Health 2007, 12: 856-861. PMID: 17596253, PMCID: PMC2570322, DOI: 10.1111/j.1365-3156.2007.01857.x.Peer-Reviewed Original ResearchConceptsBody mass indexPregnancy outcomesBirth weightInfant weightMass indexZambian womenBMI unitsLower body mass indexChild transmission ratePerinatal HIV transmissionPrevention of motherHIV viral loadInfant birth weightMean birth weightTransmission of HIVNevirapine administrationPrior stillbirthBMI quartilesCD4 countChild transmissionViral loadHIV transmissionMaternal parityUnivariate analysisClinical trials