2024
Dehydration and Suboptimal Sleep Aggravate Early Renal Impairment in Children: Longitudinal Findings from the PROC Study
Li M, Xiao H, Amaerjiang N, Thapa B, Shu W, Asihaer Y, Guan M, Vermund S, Zou Z, Huang D, Hu Y. Dehydration and Suboptimal Sleep Aggravate Early Renal Impairment in Children: Longitudinal Findings from the PROC Study. Nutrients 2024, 16: 3472. PMID: 39458467, PMCID: PMC11510355, DOI: 10.3390/nu16203472.Peer-Reviewed Original ResearchConceptsTransient renal impairmentRenal impairmentSystolic blood pressure z-scoreBody mass index z-scoreLong sleepBlood pressure z-scoreZ-scoreEarly renal impairmentOptimal sleepAssessment of sleep durationHealthy primary school childrenShort sleepMediterranean diet adherenceHydration statusAssociation of sleep durationSleep durationKidney healthMixed-effects modelsLinear mixed-effects modelsAssess longitudinal associationsMicroalbumin excretionGlomerular impairmentCohort studyDiet adherenceScreen time
2023
Risk of death and readmission among individuals with heart failure and HIV: A systematic review and meta-analysis
Zhou Y, Zhang X, Gao Y, Alvi R, Erqou S, Chen Y, Wang H, Wang W, Li X, Zanni M, Neilan T, Vermund S, Qian H, Qian F. Risk of death and readmission among individuals with heart failure and HIV: A systematic review and meta-analysis. Journal Of Infection And Public Health 2023, 17: 70-75. PMID: 37992436, DOI: 10.1016/j.jiph.2023.11.004.Peer-Reviewed Original ResearchConceptsHeart failureHF patientsRisk of HFHuman immunodeficiency virus statusPoor HF outcomesRisk of deathWeb of ScienceCause deathCause readmissionHF outcomesAdult patientsCohort studyHIV infectionHIV statusCochrane LibraryIndependent associationVirus statusHigh riskDeath outcomesHIVReadmissionPatientsSystematic reviewSystematic searchRiskValidation of “Life's Essential 8” Metrics With Cardiovascular Structural Status in Children: The PROC Study in China
Shu W, Li M, Xiao H, Amaerjiang N, Khattab N, Zunong J, Guan M, Vermund S, Hu Y. Validation of “Life's Essential 8” Metrics With Cardiovascular Structural Status in Children: The PROC Study in China. Journal Of The American Heart Association 2023, 12: e029077. PMID: 37301752, PMCID: PMC10356051, DOI: 10.1161/jaha.122.029077.Peer-Reviewed Original ResearchConceptsCarotid intima-media thicknessIntima-media thicknessCVH scoreCardiovascular healthLVM indexAbnormal sleep durationChildren's cardiovascular healthOverweight/obesityMin/wkWorse cardiovascular healthChild Cohort StudyM-mode echocardiographyAge/sexLower CVH scoreFollow-up (12- and 24-month) assessmentLipid scoreNormal BPCohort studyFasting GlucosePrimordial preventionNicotine exposureVentricular massPhysical activitySleep durationUS population
2022
Risk of SARS-CoV-2 reinfection: a systematic review and meta-analysis
Deng L, Li P, Zhang X, Jiang Q, Turner D, Zhou C, Gao Y, Qian F, Zhang C, Lu H, Zou H, Vermund S, Qian H. Risk of SARS-CoV-2 reinfection: a systematic review and meta-analysis. Scientific Reports 2022, 12: 20763. PMID: 36456577, PMCID: PMC9714387, DOI: 10.1038/s41598-022-24220-7.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 reinfectionSystematic reviewReinfection incidenceHazard ratioCase reportIncidence ratePrior SARS-CoV-2 infectionSARS-CoV-2 infectionIncidence of reinfectionInfection-naïve individualsRisk of reinfectionSARS-CoV-2 variantsRandom-effects modelSARS-CoV-2Web of ScienceCohort studyReinfection riskReinfection casesPrior infectionLower riskNew infectionsOmicron variantReinfectionInfection incidenceIncidencePassive Smoking Exposure Modifies Cardiovascular Structure and Function: Beijing Child Growth and Health Cohort (PROC) Study
Xiao H, Li M, Li A, Amaerjiang N, Zunong J, Vermund SH, Pérez-Escamilla R, Song M, Hu Y, Jiang G. Passive Smoking Exposure Modifies Cardiovascular Structure and Function: Beijing Child Growth and Health Cohort (PROC) Study. Environmental Science And Technology 2022, 56: 14585-14593. PMID: 36094430, DOI: 10.1021/acs.est.2c00991.Peer-Reviewed Original ResearchConceptsVentricular mass indexSecondhand smokeCardiovascular healthSHS exposureMass indexLow left ventricular mass indexVentricular end-diastolic volume indexVentricular end-systolic volume indexEnd-diastolic volume indexEnd-systolic volume indexLeft ventricular mass indexVentricular end-systolic diameterVolume indexChildren's cardiovascular healthPassive smoking exposureSystolic volume indexEnd-systolic diameterHealth Cohort StudyDiastolic volume indexInterventricular septum thicknessSystemic toxinsSmoking exposureCohort studySystolic diameterAorta diameterInteraction of Hydration Status and Physical Activity Level on Early Renal Damage in Children: A Longitudinal Study
Li M, Shu W, Amaerjiang N, Xiao H, Zunong J, Vermund SH, Huang D, Hu Y. Interaction of Hydration Status and Physical Activity Level on Early Renal Damage in Children: A Longitudinal Study. Frontiers In Nutrition 2022, 9: 910291. PMID: 35811990, PMCID: PMC9260418, DOI: 10.3389/fnut.2022.910291.Peer-Reviewed Original ResearchRenal tubular damageInsufficient physical activityEarly renal damageGlomerular damageRenal damageTubular damagePhysical activityPA levelsHydration statusRenal functionPrimary school childrenBMI z-scorePhysical activity levelsSufficient physical activityChild Cohort StudyPrevalence of dehydrationUrinary specific gravitySchool childrenWave 1Microalbumin excretionCohort studyRenal healthVegetable intakeSleep durationMultivariate analysisInsufficient Fruit and Vegetable Intake and Low Potassium Intake Aggravate Early Renal Damage in Children: A Longitudinal Study
Li M, Amaerjiang N, Li Z, Xiao H, Zunong J, Gao L, Vermund SH, Hu Y. Insufficient Fruit and Vegetable Intake and Low Potassium Intake Aggravate Early Renal Damage in Children: A Longitudinal Study. Nutrients 2022, 14: 1228. PMID: 35334885, PMCID: PMC8951514, DOI: 10.3390/nu14061228.Peer-Reviewed Original ResearchConceptsEarly renal damageDaily potassium intakePotassium intakeRenal damageMA excretionVegetable intakeInsufficient fruitΒ2-MGSleep durationScreen timeHigh β2-MGUrinary MA excretionUrinary β2-MGGeneral pediatric populationLow potassium intakeChild Cohort StudyShort sleep durationNon-communicable diseasesLonger screen timeMicroalbumin excretionCohort studyUrinary potassiumPediatric populationPhysical activityLifestyle statusTreatment outcomes of HIV patients with hepatitis B and C virus co-infections in Southwest China: an observational cohort study
Jia J, Zhu Q, Deng L, Lan G, Johnson A, Chen H, Shen Z, Li J, Xing H, Ruan Y, Li J, Lu H, Vermund SH, Zhu J, Qian HZ. Treatment outcomes of HIV patients with hepatitis B and C virus co-infections in Southwest China: an observational cohort study. Infectious Diseases Of Poverty 2022, 11: 7. PMID: 34986877, PMCID: PMC8734096, DOI: 10.1186/s40249-021-00921-5.Peer-Reviewed Original ResearchConceptsHepatitis B virusHepatitis C virusAntiretroviral therapyHigh mortalityHCV coinfectionC virusNational Free Antiretroviral Treatment ProgramHBV co-infected patientsHBV/HCV coinfectionRetrospective cohort study analysisEffect of ARTCohort study analysisObservational cohort studyAntiretroviral treatment programOverall mortality rateProportional hazards modelTreatment attrition rateCause deathHCV-coHIV patientsBaseline infectionCohort studyHBV-HCVHepatitis BHepatitis treatment
2021
Poor retention and care-related sex disparities among youth living with HIV in rural Mozambique
Ahonkhai AA, Aliyu MH, Audet CM, Bravo M, Simmons M, Claquin G, Memiah P, Fernando AN, Carlucci JG, Shepherd BE, Van Rompaey S, Yu Z, Gong W, Vermund SH, Wester CW. Poor retention and care-related sex disparities among youth living with HIV in rural Mozambique. PLOS ONE 2021, 16: e0250921. PMID: 34019582, PMCID: PMC8139489, DOI: 10.1371/journal.pone.0250921.Peer-Reviewed Original ResearchConceptsHigher oddsCombination antiretroviral therapy (cART) initiationCox proportional hazards modelCare continuum outcomesComprehensive HIV programsPost-ART initiationYoung adults 15Antiretroviral therapy initiationRetrospective cohort studySex-related disparitiesMultivariable logistic regressionOne-year followProportional hazards modelYears of agePL femalesSex-related differencesART initiationAYA cohortTherapy initiationCohort studyContinuum outcomesHIV outcomesClinical visitsAdults 15HIV programs
2020
HIV Seroconversion and Types of Relationships Among Men Who Have Sex With Men: A Cohort Study in China.
Sun X, Wang C, Zhao K, Zhang L, Li M, Sun D, Shu W, Ruan Y, Zhang J, Vermund SH, Li D, Hu Y. HIV Seroconversion and Types of Relationships Among Men Who Have Sex With Men: A Cohort Study in China. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2020, 83: 365-372. PMID: 31913999, PMCID: PMC7055498, DOI: 10.1097/qai.0000000000002264.Peer-Reviewed Original ResearchConceptsHIV seroconversionSeroconversion riskHIV seroconversion ratesHIV seroconversion riskMultivariable Cox regressionHIV-negative menIncident HIV infectionRegular sexual partnersRelative excess riskUnprotected anal sexSexual behaviorLast sexual encounterUnsafe sexual behaviorSafer sex educationSeroconversion ratesCohort studyHIV infectionRisky sexual behaviorHIV statusCox regressionExcess riskRisk factorsRegular partnersLow educational attainmentCasual partnersBuilding Partnerships and Stakeholder Relationships for HIV Prevention: Longitudinal Cohort Study Focuses on Community Engagement
DeShields R, Lucas J, Turner M, Amola K, Hunter V, Lykes S, Rompalo A, Vermund S, Fischer S, Haley D. Building Partnerships and Stakeholder Relationships for HIV Prevention: Longitudinal Cohort Study Focuses on Community Engagement. Progress In Community Health Partnerships Research Education And Action 2020, 14: 3-4. DOI: 10.1353/cpr.2020.0001.Peer-Reviewed Original ResearchBuilding Partnerships and Stakeholder Relationships for HIV Prevention: Longitudinal Cohort Study Focuses on Community Engagement.
DeShields RD, Lucas JP, Turner M, Amola K, Hunter V, Lykes S, Rompalo AM, Vermund SH, Fischer S, Haley DF. Building Partnerships and Stakeholder Relationships for HIV Prevention: Longitudinal Cohort Study Focuses on Community Engagement. Progress In Community Health Partnerships Research Education And Action 2020, 14: 29-42. PMID: 32280121, PMCID: PMC7228022, DOI: 10.1353/cpr.2020.0006.Peer-Reviewed Original ResearchConceptsCommunity engagementAfrican American womenCommunity engagement frameworkHIV Prevention Trials Network 064Human immunodeficiency virus (HIV) burdenHIV incidence studyLongitudinal cohort studyAmerican womenHPTN 064Community organizationsNew partnershipsVenue-based samplingBuilding partnershipsCommunity stakeholdersEngagement approachStakeholder relationshipsResearch mistrustCohort studyCommunity partnersEngagement activitiesVirus burdenHIV incidenceHIV preventionHigh prevalenceEngagement framework
2018
Severe outcomes associated with respiratory viruses in newborns and infants: a prospective viral surveillance study in Jordan
Khuri-Bulos N, Lawrence L, Piya B, Wang L, Fonnesbeck C, Faouri S, Shehabi A, Vermund SH, Williams JV, Halasa NB. Severe outcomes associated with respiratory viruses in newborns and infants: a prospective viral surveillance study in Jordan. BMJ Open 2018, 8: e021898. PMID: 29780032, PMCID: PMC5961648, DOI: 10.1136/bmjopen-2018-021898.Peer-Reviewed Original ResearchMeSH KeywordsAdenoviridaeAntiviral AgentsFemaleHumansInfantIntensive Care UnitsJordanLength of StayMaleOxygen Inhalation TherapyPalivizumabParainfluenza Virus 1, HumanProspective StudiesRespiratory Syncytial Virus InfectionsRespiratory Syncytial Virus VaccinesRespiratory Syncytial Virus, HumanRespiratory Tract InfectionsRhinovirusRisk FactorsConceptsLonger LOSLength of stayAcute respiratory infectionsIntensive care unitRespiratory syncytial virusOxygen therapyMechanical ventilationHospitalisation ratesICU admissionIllness severityRespiratory virusesMedical conditionsExtended breast feedingRSV vaccine developmentProspective cohort studyUnderlying medical conditionsChemotherapy-associated neutropeniaHuman parainfluenza virusesYears of ageCohort studyRespiratory symptomsBreast feedingRespiratory infectionsCare unitSyncytial virus
2017
Mobility and Clinic Switching Among Postpartum Women Considered Lost to HIV Care in South Africa
Clouse K, Vermund SH, Maskew M, Lurie MN, MacLeod W, Malete G, Carmona S, Sherman G, Fox MP. Mobility and Clinic Switching Among Postpartum Women Considered Lost to HIV Care in South Africa. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2017, 74: 383-389. PMID: 28225717, PMCID: PMC5324708, DOI: 10.1097/qai.0000000000001284.Peer-Reviewed Original ResearchConceptsHIV careNational Health Laboratory Service databaseLow CD4 cell countsNational Antiretroviral Therapy ProgramCD4 cell countObservational cohort studyAntiretroviral therapy programsAntiretroviral therapyCohort studyPostpartum womenPublic clinicsService databaseCell countTherapy programCareWomenLTFUClinicOne-thirdDaysPatientsPregnancyTherapyMortality in Children with Human Immunodeficiency Virus Initiating Treatment: A Six-Cohort Study in Latin America
Luque MT, Jenkins CA, Shepherd BE, Padgett D, Rouzier V, Succi RCM, Machado DM, McGowan CC, Vermund SH, Pinto JA. Mortality in Children with Human Immunodeficiency Virus Initiating Treatment: A Six-Cohort Study in Latin America. The Journal Of Pediatrics 2017, 182: 245-252.e1. PMID: 28081884, PMCID: PMC5328796, DOI: 10.1016/j.jpeds.2016.12.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveCause of DeathChildChild, PreschoolCohort StudiesConfidence IntervalsDatabases, FactualDose-Response Relationship, DrugDrug Administration ScheduleFemaleHIV InfectionsHumansIncidenceLatin AmericaMaleProportional Hazards ModelsRetrospective StudiesRisk AssessmentSeverity of Illness IndexSurvival AnalysisConceptsCombination antiretroviral therapyYears of ageCART initiationGreater riskCox proportional hazards modelAntiretroviral therapy-naïveMedian CD4 countRetrospective cohort studyProportional hazards modelCumulative mortality incidenceSouth America networkProbability of deathInitiating treatmentMedian CD4Antiretroviral therapyCause mortalityCD4 countTherapy-naïveCohort studyCumulative incidenceHIV epidemiologyPediatric careMortality incidenceHazards modelRegimens
2016
Risk Factors for Loss to Follow-Up among People Who Inject Drugs in a Risk Reduction Program at Karachi, Pakistan. A Case-Cohort Study
Samo RN, Agha A, Shah SA, Altaf A, Memon A, Blevins M, Qian HZ, Vermund SH. Risk Factors for Loss to Follow-Up among People Who Inject Drugs in a Risk Reduction Program at Karachi, Pakistan. A Case-Cohort Study. PLOS ONE 2016, 11: e0147912. PMID: 26840414, PMCID: PMC4739707, DOI: 10.1371/journal.pone.0147912.Peer-Reviewed Original ResearchConceptsCase-cohort studyMale PWIDHarm reduction programsRisk reduction programsRisk factorsReduction programsNeedle/syringe exchangeProspective cohort studyMultivariable logistic regressionResource-limited settingsHistory of incarcerationCohort studyMedian ageIncidence rateSyringe exchangePWIDMale peopleYounger ageLogistic regressionYoung menMonthsKarachiMenActive outreachProgrammatic challenges
2015
The Effect of Cryotherapy on Human Papillomavirus Clearance Among HIV-Positive Women in Lusaka, Zambia
Katundu K, Bateman AC, Pfaendler KS, Mwanahamuntu MH, Kapambwe S, Vermund SH, Sahasrabuddhe VV, Msadabwe SC, Stringer JS, Parham GP, Chibwesha CJ. The Effect of Cryotherapy on Human Papillomavirus Clearance Among HIV-Positive Women in Lusaka, Zambia. Journal Of Lower Genital Tract Disease 2015, 19: 301-306. PMID: 26125097, PMCID: PMC4583804, DOI: 10.1097/lgt.0000000000000131.Peer-Reviewed Original ResearchConceptsHIV-positive womenWeeks of treatmentHrHPV infectionHrHPV typesHigh-risk HPV cervical infectionHigh HIV burden settingsHIV burden settingsHPV cervical infectionHuman papillomavirus clearancePrevalence of hrHPVCommon HPV typesHuman papillomavirus infectionRoche Linear ArrayEffects of cryotherapyHPV vaccinationMedian CD4Antiretroviral therapyCervical infectionCohort studyPapillomavirus infectionBurden settingsCervical diseaseHPV typesMedian ageCervical screening
2014
Correlates of Suboptimal Entry Into Early Infant Diagnosis in Rural North Central Nigeria
Aliyu MH, Blevins M, Megazzini KM, Audet CM, Dunlap J, Sodangi IS, Gebi UI, Shepherd BE, Wester CW, Vermund SH. Correlates of Suboptimal Entry Into Early Infant Diagnosis in Rural North Central Nigeria. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2014, 67: e19-e26. PMID: 24853310, PMCID: PMC4134378, DOI: 10.1097/qai.0000000000000215.Peer-Reviewed Original ResearchConceptsEarly infant diagnosisRural North-Central NigeriaInfant diagnosisPregnant womenChild HIV transmission (PMTCT) programsHIV care/treatmentClinic of enrolmentPediatric HIV infectionPrevention of motherNorth Central NigeriaMultivariable logistic regressionCare/treatmentDate of enrollmentHIV service uptakeEID uptakeCohort studyHIV infectionLaboratory variablesClinic locationService uptakeMaternal factorsTransmission programInfantsReferral sourceLogistic regressionPediatric Malignancies, Treatment Outcomes and Abandonment of Pediatric Cancer Treatment in Zambia
Slone JS, Chunda-Liyoka C, Perez M, Mutalima N, Newton R, Chintu C, Kankasa C, Chipeta J, Heimburger DC, Vermund SH, Friedman DL. Pediatric Malignancies, Treatment Outcomes and Abandonment of Pediatric Cancer Treatment in Zambia. PLOS ONE 2014, 9: e89102. PMID: 24586527, PMCID: PMC3931678, DOI: 10.1371/journal.pone.0089102.Peer-Reviewed Original ResearchConceptsUniversity Teaching HospitalPediatric oncology wardOncology wardTreatment abandonmentRisk factorsTreatment outcomesRetrospective cohort studyAbandonment of treatmentMode of diagnosisCohort of childrenClinical medical recordsStudy time periodCohort studyOncologic treatmentTreatment regimenMultivariable analysisMedical recordsTeaching hospitalInclusion criteriaLower riskCancerChildrenTreatmentWardsDiagnosis
2013
High HIV Incidence among Persons Who Inject Drugs in Pakistan: Greater Risk with Needle Sharing and Injecting Frequently among the Homeless
Samo RN, Altaf A, Agha A, Pasha O, Rozi S, Memon A, Azam S, Blevins M, Vermund SH, Shah SA. High HIV Incidence among Persons Who Inject Drugs in Pakistan: Greater Risk with Needle Sharing and Injecting Frequently among the Homeless. PLOS ONE 2013, 8: e81715. PMID: 24358123, PMCID: PMC3864804, DOI: 10.1371/journal.pone.0081715.Peer-Reviewed Original ResearchConceptsIncidence of HIVHIV seroconversionIncidence rateMultivariable Cox regression analysisNeedle/syringe exchangeCohort of PWIDHIV-seronegative personsHigh HIV incidenceOpiate substitution therapyCox regression analysisHIV incidence ratesHIV risk reductionSharing of syringesRisk reductionSubstance abuse treatmentSeronegative personsCohort studyRisk reduction programsHIV incidencePerson yearsSubstitution therapyDaily injectionsNeedle sharingRisk factorsPrevalence rates