2001
Tsetse immune responses and trypanosome transmission: Implications for the development of tsetse-based strategies to reduce trypanosomiasis
Hao Z, Kasumba I, Lehane M, Gibson W, Kwon J, Aksoy S. Tsetse immune responses and trypanosome transmission: Implications for the development of tsetse-based strategies to reduce trypanosomiasis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2001, 98: 12648-12653. PMID: 11592981, PMCID: PMC60108, DOI: 10.1073/pnas.221363798.Peer-Reviewed Original ResearchConceptsFat bodyInsect immune systemAntimicrobial peptide genesFat body tissueImmune responsive genesDifferent life stagesTransgenic approachesResponsive genesAntimicrobial genesImmune responseSubtractive cloningPeptide genesAfrican trypanosomesMolecular signalsImmune systemDifferential regulationInfection processLife stagesTrypanosome transmissionParasite transmissionGenesImportant vectorEscherichia coliBiochemical natureDiptericin
1997
Prevention of insect-borne disease: An approach using transgenic symbiotic bacteria
Durvasula R, Gumbs A, Panackal A, Kruglov O, Aksoy S, Merrifield R, Richards F, Beard C. Prevention of insect-borne disease: An approach using transgenic symbiotic bacteria. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 3274-3278. PMID: 9096383, PMCID: PMC20359, DOI: 10.1073/pnas.94.7.3274.Peer-Reviewed Original ResearchConceptsSymbiotic bacteriaDisease-transmitting insectsChagas disease vectorsSymbiont acquisitionTransgenic bacteriaInsect-borne diseaseR. prolixusDisease vectorsCertain arthropodsRhodnius prolixusT. cruziTrypanosoma cruziCecropin AExpression of moleculesInsectsBacteriaPowerful approachProlixusCruziExpressionEndosymbiontsArthropodsCecropinAntiparasitic activityParasites