2012
Obligate Symbionts Activate Immune System Development in the Tsetse Fly
Weiss BL, Maltz M, Aksoy S. Obligate Symbionts Activate Immune System Development in the Tsetse Fly. The Journal Of Immunology 2012, 188: 3395-3403. PMID: 22368278, PMCID: PMC3311772, DOI: 10.4049/jimmunol.1103691.Peer-Reviewed Original ResearchConceptsSymbiotic bacteriaImmune system developmentNovel evolutionary adaptationImmunity-related genesObligate symbiontsSymbiotic microbesObligate mutualistsViviparous modeProper immune system functionEvolutionary adaptationPhagocytic hemocytesMolecular mechanismsCell extractsMolecular componentsSusceptible phenotypeNonpathogenic Escherichia coliEscherichia coliTsetse fliesImmune systemFliesAtypical expressionHemocytesImmune system functionPhenotypeTsetse
2007
Refractoriness in Tsetse Flies (Diptera: Glossinidae) May be a Matter of Timing
Nayduch D, Aksoy S. Refractoriness in Tsetse Flies (Diptera: Glossinidae) May be a Matter of Timing. Journal Of Medical Entomology 2007, 51 DOI: 10.1603/0022-2585(2007)44[660:ritfdg]2.0.co;2.Peer-Reviewed Original ResearchAttacin expressionTsetse fliesReverse geneticsRNA interferenceFly speciesGene expressionAttacinCertain speciesSusceptible speciesBlood feedingSpeciesVector competenceFliesImmune challengeEfficient vectorDevastating diseaseExpressionRefractory speciesTsetseG. pallidipesAfrican trypanosomiasisHumoral immune responseSalivary glandsRepressionDisease transmissionRefractoriness in Tsetse Flies (Diptera: Glossinidae) May be a Matter of Timing
Nayduch D, Aksoy S. Refractoriness in Tsetse Flies (Diptera: Glossinidae) May be a Matter of Timing. Journal Of Medical Entomology 2007, 44: 660-665. DOI: 10.1603/0022-2585%282007%2944%5b660%3aritfdg%5d2.0.co%3b2.Peer-Reviewed Original ResearchAttacin expressionTsetse fliesReverse geneticsRNA interferenceFly speciesGene expressionAttacinCertain speciesSusceptible speciesBlood feedingSpeciesVector competenceFliesImmune challengeEfficient vectorSusceptible fliesDevastating diseaseExpressionRefractory speciesTsetseG. pallidipesAfrican trypanosomiasisHumoral immune responseSalivary glandsRepression
2002
Tsetse Vector Based Strategies for Control of African Try Panosomiasis
Aksoy S. Tsetse Vector Based Strategies for Control of African Try Panosomiasis. 2002, 1: 39-49. DOI: 10.1007/0-306-46894-8_4.Peer-Reviewed Original ResearchMolecular genetic approachesBacterial symbiontsRecombinant DNA technologySymbiotic bacteriaCytoplasmic incompatibilityWolbachia symbiontsPotential genesGenetic approachesParasite biologyForeign genesSusceptible counterpartsDNA technologySymbiontsGenesSame tissueInsectsDisease transmissionOrganismsBiologyTrypanosomesBacteriaExpressionNew strategyTsetse
2001
Prospects for control of African trypanosomiasis by tsetse vector manipulation
Aksoy S, O'Neill S, Maudlin I, Dale C, Robinson A. Prospects for control of African trypanosomiasis by tsetse vector manipulation. Trends In Parasitology 2001, 17: 29-35. PMID: 11137738, DOI: 10.1016/s1471-4922(00)01850-x.Peer-Reviewed Original ResearchConceptsArea-wide approachHuman disease managementLivestock ownersAnimal diseasesAgricultural outputMolecular genetic approachesImportant insectsInfected hostDisease managementEconomic incentivesTsetse populationsVector manipulationGenetic approachesMammalian hostsVector competenceEffective vaccineDiseases reliesHostTrypanosomiasisControl strategyInsectsAfrican trypanosomiasisTsetseLong runControl