Efficacy and safety of ketamine-assisted electroconvulsive therapy in major depressive episode: a systematic review and network meta-analysis
Rhee T, Shim S, Popp J, Trikalinos T, Rosenheck R, Kellner C, Seiner S, Espinoza R, Forester B, McIntyre R. Efficacy and safety of ketamine-assisted electroconvulsive therapy in major depressive episode: a systematic review and network meta-analysis. Molecular Psychiatry 2023, 29: 750-759. PMID: 38123725, DOI: 10.1038/s41380-023-02366-8.Peer-Reviewed Original ResearchMajor depressive episodeStandardized mean differenceElectroconvulsive therapyAnesthetic agentsDepressive symptomsDepressive episodeRelative riskDiagnosis of MDESystematic reviewKetamine-treated patientsSafety of ketamineSerious adverse eventsResultsTwenty-two studiesMethodsPubMed/MEDLINEImportant clinical considerationsRandom-effects modelCognitive performanceAdverse eventsAntidepressant efficacyECT useTrials RegistryClinical efficacyCochrane LibraryWorse outcomesPatient profilesReceipt of Electroconvulsive Therapy in Outpatient Settings in a National Sample of Privately Insured Patients With Mood Disorders
Agbese E, Leslie D, Rosenheck R. Receipt of Electroconvulsive Therapy in Outpatient Settings in a National Sample of Privately Insured Patients With Mood Disorders. Journal Of Ect 2023, 40: 31-36. PMID: 37530796, DOI: 10.1097/yct.0000000000000950.Peer-Reviewed Original ResearchConceptsElectroconvulsive therapyReduce cost barriersMood disordersHealth care costsOutpatient settingPrivately insured patientsCare costsNational sample of privately insured patientsProportion of privately insured patientsReceipt of electroconvulsive therapyInpatient electroconvulsive therapyCost barriersOutpatient electroconvulsive therapyMarketScan Commercial DatabaseDepressive disorderCompared 4 groupsGroup differencesInpatient settingMoodNational sampleEffective treatmentPatientsDisordersOutpatientsHealth