2018
All-cause mortality among people with HIV released from an integrated system of jails and prisons in Connecticut, USA, 2007–14: a retrospective observational cohort study
Loeliger KB, Altice FL, Ciarleglio MM, Rich KM, Chandra DK, Gallagher C, Desai MM, Meyer JP. All-cause mortality among people with HIV released from an integrated system of jails and prisons in Connecticut, USA, 2007–14: a retrospective observational cohort study. The Lancet HIV 2018, 5: e617-e628. PMID: 30197101, PMCID: PMC6279524, DOI: 10.1016/s2352-3018(18)30175-9.Peer-Reviewed Original ResearchConceptsIndex releaseCause mortalityMortality rateRetrospective observational cohort studyCox proportional hazards modelLow CD4 countObservational cohort studyHIV surveillance dataCrude mortality rateGeneral US populationProportional hazards modelStandardised mortality ratiosSubstance use disordersSystems of careHIV/AIDSSurvival of peopleVirological failureAntiretroviral therapyCD4 countMedical comorbiditiesCohort studyRetrospective cohortMedian ageLiver diseaseViral load
2015
National Trends in Pulmonary Embolism Hospitalization Rates and Outcomes for Adults Aged ≥65 Years in the United States (1999 to 2010)
Minges KE, Bikdeli B, Wang Y, Kim N, Curtis JP, Desai MM, Krumholz HM. National Trends in Pulmonary Embolism Hospitalization Rates and Outcomes for Adults Aged ≥65 Years in the United States (1999 to 2010). The American Journal Of Cardiology 2015, 116: 1436-1442. PMID: 26409636, PMCID: PMC4841688, DOI: 10.1016/j.amjcard.2015.07.068.Peer-Reviewed Original ResearchConceptsHospitalization ratesMortality rateReadmission ratesBlack patientsPrincipal discharge diagnosis codeOlder adultsCause readmission rateHospital mortality rateProportion of patientsRetrospective cohort studyDischarge diagnosis codesSkilled nursing facilitiesNational trendsSignificant racial differencesHigh rateHome health careHospital stayAdults AgedCohort studyMore patientsTherapeutic advancesDiagnosis codesMedicare feeNursing facilitiesSignificant burden
2014
Trends in Aortic Dissection Hospitalizations, Interventions, and Outcomes Among Medicare Beneficiaries in the United States, 2000–2011
Mody PS, Wang Y, Geirsson A, Kim N, Desai MM, Gupta A, Dodson JA, Krumholz HM. Trends in Aortic Dissection Hospitalizations, Interventions, and Outcomes Among Medicare Beneficiaries in the United States, 2000–2011. Circulation Cardiovascular Quality And Outcomes 2014, 7: 920-928. PMID: 25336626, PMCID: PMC4380171, DOI: 10.1161/circoutcomes.114.001140.Peer-Reviewed Original ResearchTrends in left ventricular assist device use and outcomes among Medicare beneficiaries, 2004–2011
Lampropulos JF, Kim N, Wang Y, Desai MM, Barreto-Filho JA, Dodson JA, Dries DL, Mangi AA, Krumholz HM. Trends in left ventricular assist device use and outcomes among Medicare beneficiaries, 2004–2011. Open Heart 2014, 1: e000109. PMID: 25332817, PMCID: PMC4189322, DOI: 10.1136/openhrt-2014-000109.Peer-Reviewed Original ResearchDischarge dispositionLVAD implantationMortality rateRehospitalisation ratesIndex hospitalisationImplantation rateLeft ventricular assist device useVentricular assist device useMedicaid Services paymentsProportion of patientsLong-term outcomesPost-procedure lengthUse of LVADsDevice implantation ratesHospital daysHospitalisation costsHeartMate IILVAD useMedicare feeMedicare populationMedicare beneficiariesService beneficiariesHospitalisationDevice useStayUsual Source of Care and Outcomes Following Acute Myocardial Infarction
Spatz ES, Sheth SD, Gosch KL, Desai MM, Spertus JA, Krumholz HM, Ross JS. Usual Source of Care and Outcomes Following Acute Myocardial Infarction. Journal Of General Internal Medicine 2014, 29: 862-869. PMID: 24553957, PMCID: PMC4026492, DOI: 10.1007/s11606-014-2794-0.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionUsual sourceMyocardial infarctionMortality rateBaseline risk factorsAcute clinical eventsMain outcome measuresAMI severityAMI patientsMultivariable analysisKey ResultsAmongClinical eventsSocio-demographic characteristicsRisk factorsOutcome measuresReadmissionHigh mortalityPatientsMortalityCareMonthsInfarctionAdultsOutcomesAssociation
2013
Trends in Intracranial Stenting Among Medicare Beneficiaries in the United States, 2006–2010
Gupta A, Desai MM, Kim N, Bulsara KR, Wang Y, Krumholz HM. Trends in Intracranial Stenting Among Medicare Beneficiaries in the United States, 2006–2010. Journal Of The American Heart Association 2013, 2: e000084. PMID: 23588099, PMCID: PMC3647283, DOI: 10.1161/jaha.113.000084.Peer-Reviewed Original ResearchConceptsIntracranial stentingMortality rateService beneficiariesICD-9-CM procedure codesPrincipal discharge diagnosis codeOverall hospitalization rateDischarge diagnosis codesHumanitarian Device Exemption approvalAcute care hospitalsHumanitarian Device ExemptionCare hospitalIntracranial angioplastyHospitalization ratesICS useSubarachnoid hemorrhageDiagnosis codesOperative rateProcedure ratesMedicare feeMedicare beneficiariesInsufficient evidenceICS procedureDrug AdministrationCerebral aneurysmsMedicaid Services
2012
Hospital-Level Outcomes Associated with Laparoscopic Colectomy for Cancer in the Minimally Invasive Era
Fox JP, Desai MM, Krumholz HM, Gross CP. Hospital-Level Outcomes Associated with Laparoscopic Colectomy for Cancer in the Minimally Invasive Era. Journal Of Gastrointestinal Surgery 2012, 16: 2112-2119. PMID: 22948842, PMCID: PMC3670114, DOI: 10.1007/s11605-012-2018-z.Peer-Reviewed Original ResearchConceptsLaparoscopy rateLaparoscopic colectomyShorter hospitalizationColon resectionHospital mortalityPostoperative morbidityLow postoperative morbidity rateHigher laparoscopy ratePostoperative morbidity rateRisk-standardized outcomesLow postoperative morbidityShorter hospital stayNationwide Inpatient SampleShort-term outcomesHigher procedure volumeHospital stayComparable morbidityRandomized trialsMorbidity rateInvasive eraInpatient SampleOutcomes AssociatedColectomyMortality rateProcedure volumeCorrelations among risk‐standardized mortality rates and among risk‐standardized readmission rates within hospitals
Horwitz LI, Wang Y, Desai MM, Curry LA, Bradley EH, Drye EE, Krumholz HM. Correlations among risk‐standardized mortality rates and among risk‐standardized readmission rates within hospitals. Journal Of Hospital Medicine 2012, 7: 690-696. PMID: 22865546, PMCID: PMC3535010, DOI: 10.1002/jhm.1965.Peer-Reviewed Original ResearchConceptsRisk-standardized mortality ratesAcute myocardial infarctionRisk-standardized readmission ratesReadmission ratesRisk-standardized mortalityHeart failureMortality rateReadmission measuresUS hospitalsMortality measuresCross-sectional studyMortality cohortReadmission cohortHospital outcomesSame hospitalMyocardial infarctionMedicare patientsMedicare feeService beneficiariesTeaching hospital membersHospitalSame quartileHospital membersPneumoniaCohortOutcomes for Mitral Valve Surgery Among Medicare Fee-for-Service Beneficiaries, 1999 to 2008
Dodson JA, Wang Y, Desai MM, Barreto-Filho JA, Sugeng L, Hashim SW, Krumholz HM. Outcomes for Mitral Valve Surgery Among Medicare Fee-for-Service Beneficiaries, 1999 to 2008. Circulation Cardiovascular Quality And Outcomes 2012, 5: 298-307. PMID: 22576847, PMCID: PMC3400109, DOI: 10.1161/circoutcomes.112.966077.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overChi-Square DistributionFee-for-Service PlansFemaleHealthcare DisparitiesHeart Valve DiseasesHeart Valve Prosthesis ImplantationHospital MortalityHospitalizationHumansLinear ModelsMaleMedicareMitral ValveOdds RatioPatient ReadmissionQuality ImprovementRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsMitral valve surgeryValve surgeryMitral valve repairFFS patientsHospitalization ratesValve repairMedicare feeMedicare Standard Analytic FilesMedicare FFS patientsRisk-standardized ratesProportion of patientsStandard Analytic FilesVital Status filesNational surveillance dataMedicare administrative dataSubstantial morbidityMortality outcomesService patientsAnalytic FilesMortality riskMortality rateSurgeryPatientsDenominator fileReadmission
2003
Trends in Discharge Disposition, Mortality, and Service Use Among Long-Stay Psychiatric Patients in the 1990s
Desai MM, Rosenheck RA. Trends in Discharge Disposition, Mortality, and Service Use Among Long-Stay Psychiatric Patients in the 1990s. Psychiatric Services 2003, 54: 542-548. PMID: 12663843, DOI: 10.1176/appi.ps.54.4.542.Peer-Reviewed Original ResearchMeSH KeywordsAffective Disorders, PsychoticAgedBrain DiseasesCensusesCohort StudiesFemaleHealth Facility ClosureHospital MortalityHospitals, VeteransHumansLength of StayMaleMental Health ServicesMentally Ill PersonsMiddle AgedPatient DischargePsychotic DisordersUnited StatesUnited States Department of Veterans AffairsUtilization ReviewConceptsDischarge dispositionThree-year followService usePrincipal diagnosisPsychiatric patientsVA mental health servicesLong-stay psychiatric patientsLong-stay bedsLong-stay cohortsStay Psychiatric PatientsVA administrative databasesMental health bedsMental health inpatientsLong-term inpatientsVA service useMental health servicesPatient's principal diagnosisMental health systemFiscal year 1991Administrative databasesMortality ratePsychotic disordersHealth servicesPatientsCohortBurden of Illness Score for Elderly Persons
Inouye SK, Bogardus ST, Vitagliano G, Desai MM, Williams CS, Grady JN, Scinto JD. Burden of Illness Score for Elderly Persons. Medical Care 2003, 41: 70-83. PMID: 12544545, DOI: 10.1097/00005650-200301000-00010.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overCohort StudiesComorbidityCost of IllnessFemaleFollow-Up StudiesForecastingGeriatric AssessmentHealth StatusHospitalizationHospitals, TeachingHumansMaleMortalityPneumoniaProbabilityProportional Hazards ModelsRisk AdjustmentRisk FactorsSeverity of Illness IndexSex FactorsSurvival AnalysisTime FactorsConceptsGroup IHazard ratioIllness scoresOverall mortalityC-statisticElderly personsHospitalized older personsHigh-risk diagnosesRisk adjustment indexProspective cohortValidation cohortDevelopment cohortUniversity HospitalPhysiologic abnormalitiesRisk factorsFunctional impairmentRisk groupsMedicine serviceMortality predictionMortality rateGroup IICohortOlder personsFinal modelGroup III
2002
Development and Validation of a Risk‐Adjustment Index for Older Patients: The High‐Risk Diagnoses for the Elderly Scale
Desai MM, Bogardus ST, Williams CS, Vitagliano G, Inouye SK. Development and Validation of a Risk‐Adjustment Index for Older Patients: The High‐Risk Diagnoses for the Elderly Scale. Journal Of The American Geriatrics Society 2002, 50: 474-481. PMID: 11943043, DOI: 10.1046/j.1532-5415.2002.50113.x.Peer-Reviewed Original ResearchConceptsRisk adjustment indexDevelopment cohortElderly ScaleRisk diagnosisProspective cohort studyGeneral medical patientsGeneral medicine serviceUniversity Teaching HospitalCox proportional hazardsCharacteristic curve analysisComparable patientsCohort studyOlder patientsStrength of associationDischarge diagnosisMedical patientsValidation cohortRisk groupsTeaching hospitalInitial cohortMortality riskSeparate cohortMedicine serviceMortality ratePatients