2019
Mendelian randomization provides support for obesity as a risk factor for meningioma
Takahashi H, Cornish AJ, Sud A, Law PJ, Disney-Hogg L, Calvocoressi L, Lu L, Hansen HM, Smirnov I, Walsh KM, Schramm J, Hoffmann P, Nöthen MM, Jöckel KH, Schildkraut JM, Simon M, Bondy M, Wrensch M, Wiemels JL, Claus EB, Turnbull C, Houlston RS. Mendelian randomization provides support for obesity as a risk factor for meningioma. Scientific Reports 2019, 9: 309. PMID: 30670737, PMCID: PMC6343031, DOI: 10.1038/s41598-018-36186-6.Peer-Reviewed Original ResearchConceptsRisk of meningiomaMeningioma riskObesity-related traitsLipoprotein cholesterolBlood pressureRisk factorsOdds ratioLow-density lipoprotein cholesterolHigh-density lipoprotein cholesterolMendelian randomizationCause of meningiomaGenetic instrumentsDiastolic blood pressureEpidemiological observational studiesSystolic blood pressureBody mass indexBody fat percentageWaist circumferenceTotal cholesterolMass indexObservational studyMeningioma patientsMeningiomasBasal metabolic rateObesity
2014
Endogenous and exogenous hormone exposure and the risk of meningioma in men.
Schildkraut JM, Calvocoressi L, Wang F, Wrensch M, Bondy ML, Wiemels JL, Claus EB. Endogenous and exogenous hormone exposure and the risk of meningioma in men. Journal Of Neurosurgery 2014, 120: 820-6. PMID: 24484233, PMCID: PMC4386752, DOI: 10.3171/2013.12.jns131170.Peer-Reviewed Original ResearchConceptsBody mass indexMeningioma riskOdds ratioHigher body mass indexExogenous hormone exposureMultivariate logistic regressionRelated risk factorsConfidence intervalsRisk of meningiomaPrevalence of exposureConsiderable morbidityMale patientsMass indexRisk factorsEndogenous estrogensReduced riskHormonal factorsHormone exposureIntracranial meningiomasExogenous exposureMeningiomasLogistic regressionUse of soyMenRisk
2012
Exogenous hormone use, reproductive factors, and risk of intracranial meningioma in females.
Claus EB, Calvocoressi L, Bondy ML, Wrensch M, Wiemels JL, Schildkraut JM. Exogenous hormone use, reproductive factors, and risk of intracranial meningioma in females. Journal Of Neurosurgery 2012, 118: 649-56. PMID: 23101448, PMCID: PMC3756881, DOI: 10.3171/2012.9.jns12811.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge of OnsetAgedBody Mass IndexBreast FeedingConnecticutContraceptives, OralEstrogen Replacement TherapyFemaleHumansMassachusettsMenarcheMeningeal NeoplasmsMeningiomaMenopauseMiddle AgedMultivariate AnalysisNorth CarolinaOdds RatioParityRegistriesReproductive HistoryRisk AssessmentRisk FactorsSan FranciscoSmokingTexasConceptsBody mass indexMeningioma riskMass indexIntracranial meningiomasExogenous hormone useHormone replacement therapyRisk of meningiomaYears of ageCurrent useResidents of ConnecticutHormone medicationWomen 29Postmenopausal womenPremenopausal womenCurrent smokingFertility medicationsOral contraceptivesHormone useMenstrual factorsSignificant positive associationCigarette smokingReplacement therapyRisk factorsReproductive factorsSignificant elevationDental x‐rays and risk of meningioma
Claus EB, Calvocoressi L, Bondy ML, Schildkraut JM, Wiemels JL, Wrensch M. Dental x‐rays and risk of meningioma. Cancer 2012, 118: 4530-4537. PMID: 22492363, PMCID: PMC3396782, DOI: 10.1002/cncr.26625.Peer-Reviewed Original ResearchConceptsRisk of meningiomaDental X-raysModifiable risk factorsIntracranial meningiomasRisk factorsAge 20Population-based case-control studyMain outcome measuresPrimary brain tumorsCase-control studyGreater frequencyPanorex filmsTumor locationBitewing examinationOutcome measuresElevated riskBrain tumorsControl groupMeningiomasYounger ageRadiation exposureAge 10AgePatientsRisk
2011
Reduced allergy and immunoglobulin E among adults with intracranial meningioma compared to controls
Wiemels JL, Wrensch M, Sison JD, Zhou M, Bondy M, Calvocoressi L, Black PM, Yu H, Schildkraut JM, Claus EB. Reduced allergy and immunoglobulin E among adults with intracranial meningioma compared to controls. International Journal Of Cancer 2011, 129: 1932-1939. PMID: 21520030, PMCID: PMC3337969, DOI: 10.1002/ijc.25858.Peer-Reviewed Original ResearchConceptsAtopic allergyLower total serum IgEPhysician-diagnosed allergyRole of allergyTotal serum IgEHistory of allergyCentral nervous systemRandom digit dialingSerum IgESerum levelsFrequent tumorsRisk factorsIntracranial meningiomasAllergyImmune processesNervous systemMeningiomasStudy participantsNatural historyConsortium studyInverse relationshipFurther researchParticipantsIgEGeographic areas