2023
Disparities in stage at diagnosis for liver cancer in China
Shan T, Ran X, Li H, Feng G, Zhang S, Zhang X, Zhang L, Lu L, An L, Fu R, Sun K, Wang S, Chen R, Li L, Chen W, Wei W, Zeng H, He J. Disparities in stage at diagnosis for liver cancer in China. Journal Of The National Cancer Center 2023, 3: 7-13. PMID: 39036312, PMCID: PMC11256694, DOI: 10.1016/j.jncc.2022.12.002.Peer-Reviewed Original ResearchLiver cancerStage IIIStage distributionHospital-based studyProportion of patientsLiver Cancer stagePrimary liver cancerCancer control policiesCancer awarenessCancer stageTreatment strategiesFamily historyStudy populationStage ISocioeconomic populationsCancerLogistic regressionPatientsDiagnosisEarly detectionHigher proportionDifferent populationsPopulationProportionHospital
2021
A Circulating Exosome RNA Signature Is a Potential Diagnostic Marker for Pancreatic Cancer, a Systematic Study
Wu Y, Zeng H, Yu Q, Huang H, Fervers B, Chen ZS, Lu L. A Circulating Exosome RNA Signature Is a Potential Diagnostic Marker for Pancreatic Cancer, a Systematic Study. Cancers 2021, 13: 2565. PMID: 34073722, PMCID: PMC8197236, DOI: 10.3390/cancers13112565.Peer-Reviewed Original ResearchPancreatic cancerHealthy individualsRNA signatureChronic pancreatitisHealthy controlsExosome RNASimilar differential patternsPancreatic cancer detectionPotential diagnostic markerDisease stageTumor tissueCancerDiagnostic markerEarly detectionPancreatitisSignificant differencesCancer detectionDifferential patternsDifferential expressionExosomesExosome proteinsRNA-seq dataIndividualsRNAPatients
2016
Epithelial splicing regulatory protein 1 and 2 paralogues correlate with splice signatures and favorable outcome in human colorectal cancer
Deloria AJ, Höflmayer D, Kienzl P, Łopatecka J, Sampl S, Klimpfinger M, Braunschmid T, Bastian F, Lu L, Marian B, Stättner S, Holzmann K. Epithelial splicing regulatory protein 1 and 2 paralogues correlate with splice signatures and favorable outcome in human colorectal cancer. Oncotarget 2016, 5: 73800-73816. PMID: 27650542, PMCID: PMC5342015, DOI: 10.18632/oncotarget.12070.Peer-Reviewed Original ResearchConceptsColorectal cancerEpithelial-mesenchymal transitionPrognostic valueNon-neoplastic colorectal epitheliumPrognosis of CRCFavorable overall survivalHuman colorectal cancerRole of ESRP1Overall survivalCRC casesPathological stageCRC cellsPrognostic stratificationFavorable outcomeTumor stagingClinical dataTCGA cohortColorectal epitheliumTumor progressionMicrosatellite instabilityMicrosatellite stabilityTumor cellsEarly detectionProtein 1Tissue expressionExosomes: potential for early detection in pancreatic cancer
Lu L, Risch HA. Exosomes: potential for early detection in pancreatic cancer. Future Oncology 2016, 12: 1081-1090. PMID: 26860951, DOI: 10.2217/fon-2015-0005.Peer-Reviewed Original Research