2013
Effect of Exercise on Metabolic Syndrome Variables in Breast Cancer Survivors
Thomas GA, Alvarez-Reeves M, Lu L, Yu H, Irwin ML. Effect of Exercise on Metabolic Syndrome Variables in Breast Cancer Survivors. International Journal Of Endocrinology 2013, 2013: 168797. PMID: 24319454, PMCID: PMC3844242, DOI: 10.1155/2013/168797.Peer-Reviewed Original ResearchBreast cancer survivorsMetabolic syndromeCancer survivorsExercise interventionUsual careChronic diseasesMetabolic syndrome Z-scoreObese breast cancer survivorsPostmenopausal breast cancer survivorsOverall metabolic syndromeMetabolic syndrome prevalenceComorbid chronic diseasesAerobic exercise interventionMetabolic syndrome variablesUsual care interventionsEffects of exerciseLifestyle interventionSyndrome prevalenceAerobic exerciseCare interventionsHigh prevalenceExercise adherenceTotal womenSyndromeZ-score
2011
Physical activity and breast cancer survival: an epigenetic link through reduced methylation of a tumor suppressor gene L3MBTL1
Zeng H, Irwin ML, Lu L, Risch H, Mayne S, Mu L, Deng Q, Scarampi L, Mitidieri M, Katsaros D, Yu H. Physical activity and breast cancer survival: an epigenetic link through reduced methylation of a tumor suppressor gene L3MBTL1. Breast Cancer Research And Treatment 2011, 133: 127-135. PMID: 21837478, DOI: 10.1007/s10549-011-1716-7.Peer-Reviewed Original ResearchMeSH KeywordsBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, LobularChromosomal Proteins, Non-HistoneDNA MethylationEpigenesis, GeneticFemaleGene ExpressionGene Expression ProfilingGene Expression Regulation, NeoplasticGenes, Tumor SuppressorHumansKaplan-Meier EstimateMotor ActivityRepressor ProteinsTumor Suppressor ProteinsConceptsBreast cancer patientsBreast cancer survivalCancer patientsPhysical activityOverall survivalSurvival outcomesTumor suppressor geneCancer survivalHormone receptor-positive tumorsModerate-intensity aerobic exerciseHigh expressionBreast cancer deathsReceptor-positive tumorsRandomized clinical trialsExercise-related changesSuppressor genePeripheral blood leukocytesBreast cancer diagnosisGene expressionDisease recurrenceAerobic exerciseCancer deathClinical trialsTumor featuresBlood leukocytes