2020
Clinical, Epidemiological and Experimental Approaches to Assess Adverse Health Outcomes of Indoor Biomass Smoke Exposure: Conclusions from An Indo-Swedish Workshop in Mysuru, January 2020
Anand M, Larsson K, Johanson G, Phuleria HC, Ravindra PV, Ernstgård L, Mabalirajan U, Krishna M, Palmberg L, Pollitt KJG, Upadhyay S, Ganguly K. Clinical, Epidemiological and Experimental Approaches to Assess Adverse Health Outcomes of Indoor Biomass Smoke Exposure: Conclusions from An Indo-Swedish Workshop in Mysuru, January 2020. Toxics 2020, 8: 68. PMID: 32899560, PMCID: PMC7560295, DOI: 10.3390/toxics8030068.Peer-Reviewed Original ResearchAdverse health effectsHealth effectsBiomass smoke exposureAdverse health outcomesPotential protective mechanismDeterminants of healthSmoke exposureEpidemiological field studiesHealth outcomesAdult cohortDietary exposureVivo modelProtective mechanismPersonalized exposure assessmentExposure assessmentStudy objectiveNew screening methodExposureMysuruMulti-disciplinary approachFuture studiesOutcomesSpecific aimScreening methodPlausible strategy
2016
Murine precision-cut lung slices exhibit acute responses following exposure to gasoline direct injection engine emissions
Maikawa CL, Zimmerman N, Rais K, Shah M, Hawley B, Pant P, Jeong CH, Delgado-Saborit JM, Volckens J, Evans G, Wallace JS, Pollitt K. Murine precision-cut lung slices exhibit acute responses following exposure to gasoline direct injection engine emissions. The Science Of The Total Environment 2016, 568: 1102-1109. PMID: 27369091, DOI: 10.1016/j.scitotenv.2016.06.173.Peer-Reviewed Original ResearchConceptsLung slicesPulmonary responseBALB/c miceMurine precision-cut lung slicesOxidative stressPrecision-cut lung slicesOxidative stress markersOne-hour exposurePulmonary effectsC miceGDI engine exhaustAcute responseCYP1B1 expressionStress markersVivo modelPolycyclic aromatic hydrocarbon metabolismUpregulation of genesElectrostatic aerosolParticulate fractionAromatic hydrocarbon metabolismExposureUpregulated genesMRNA productionMetabolismAir-liquid interface