2016
Fine Particulate Matter and Emergency Room Visits for Respiratory Illness. Effect Modification by Oxidative Potential
Weichenthal SA, Lavigne E, Evans GJ, Pollitt K, Burnett RT. Fine Particulate Matter and Emergency Room Visits for Respiratory Illness. Effect Modification by Oxidative Potential. American Journal Of Respiratory And Critical Care Medicine 2016, 194: 577-86. PMID: 26963193, DOI: 10.1164/rccm.201512-2434oc.Peer-Reviewed Original ResearchConceptsEmergency room visitsAcute respiratory morbidityRespiratory illnessRoom visitsImpact of PM2.5Respiratory morbidityChronic obstructive pulmonary diseaseAcute respiratory illnessObstructive pulmonary diseaseFine particulate air pollutionCases of asthmaConditional logistic regressionCase-crossover studyParticulate air pollutionRespiratory outcomesPulmonary diseaseEmergency roomEffect modificationRespiratory tractDaily air pollution dataInterquartile changeTime-varying covariatesOxidative burdenIllnessLogistic regressionParticulate Oxidative Burden as a Predictor of Exhaled Nitric Oxide in Children with Asthma
Maikawa CL, Weichenthal S, Wheeler AJ, Dobbin NA, Smargiassi A, Evans G, Liu L, Goldberg MS, Pollitt KJ. Particulate Oxidative Burden as a Predictor of Exhaled Nitric Oxide in Children with Asthma. Environmental Health Perspectives 2016, 124: 1616-1622. PMID: 27152705, PMCID: PMC5047770, DOI: 10.1289/ehp175.Peer-Reviewed Original ResearchOxidative burdenAirway inflammationNitric oxideAsthmatic school-aged childrenExhaled Nitric OxideReactive oxygen speciesPM2.5 personal exposureFeNO levelsFeNO responseCorticosteroid useAsthmatic symptomsAsthmatic childrenSchool-aged childrenRespiratory tractOxygen speciesEpidemiological studiesFeNOFluid liningConsecutive daysPersonal exposurePersonal exposure samplesAsthmaBurdenAllergyChildren
2015
Oxidative burden of fine particulate air pollution and risk of cause-specific mortality in the Canadian Census Health and Environment Cohort (CanCHEC)
Weichenthal S, Crouse DL, Pinault L, Godri-Pollitt K, Lavigne E, Evans G, van Donkelaar A, Martin RV, Burnett RT. Oxidative burden of fine particulate air pollution and risk of cause-specific mortality in the Canadian Census Health and Environment Cohort (CanCHEC). Environmental Research 2015, 146: 92-99. PMID: 26745732, DOI: 10.1016/j.envres.2015.12.013.Peer-Reviewed Original ResearchConceptsCause-specific mortalityFine particulate air pollutionOxidative burdenParticulate air pollutionHazard ratioLung cancer hazard ratiosLong-term mortality riskCox proportional hazards modelCanadian Census HealthCancer hazard ratioLung cancer mortalityRisk of mortalityProportional hazards modelRespiratory tract lining fluidCanadian Long Form CensusEnvironment CohortSynthetic respiratory tract lining fluidCancer mortalityLung cancerLining fluidMortality riskHazards modelIndividual-level covariatesInterquartile changeLong-form census