Ambient particulate matter oxidative potential: Chemical determinants, associated health effects, and strategies for risk management
Gao D, Ripley S, Weichenthal S, Godri Pollitt KJ. Ambient particulate matter oxidative potential: Chemical determinants, associated health effects, and strategies for risk management. Free Radical Biology And Medicine 2020, 151: 7-25. PMID: 32430137, DOI: 10.1016/j.freeradbiomed.2020.04.028.Peer-Reviewed Original ResearchConceptsOxidative potentialRedox-active metalsRedox propertiesPM chemical constituentsOrganic speciesPM oxidative potentialTarget moleculesFine PM massOP assaysChemical constituentsChemical determinantsParticulate matter toxicityOP responseMass concentrationAssociated health effectsPM speciesAir pollution exposure assessmentMetalsEpidemiological studiesHealth outcomesEpidemiologic literaturePollution exposure assessmentHealth effectsRedoxExposure assessmentCharacterization and comparison of PM2.5 oxidative potential assessed by two acellular assays
Gao D, Pollitt K, Mulholland J, Russell A, Weber R. Characterization and comparison of PM2.5 oxidative potential assessed by two acellular assays. Atmospheric Chemistry And Physics 2020, 20: 5197-5210. DOI: 10.5194/acp-20-5197-2020.Peer-Reviewed Original ResearchWater-soluble CuOP assaysMetal ionsOxidative potentialMetal-metal interactionsChemical componentsHumic-like substancesAscorbic acidSynthetic respiratory tract lining fluidDepletion of dithiothreitolMetal speciesOrganic compoundsPM2.5 oxidative potentialBrown carbonMajor chemical componentsOPGSHIonsRespiratory tract lining fluidAcellular assaysParticle composition dataElemental carbonCuCarbonOPAAOPDTT