Comparison of Airway Responses Induced in a Mouse Model by the Gas and Particulate Fractions of Gasoline Direct Injection Engine Exhaust
Maikawa CL, Zimmerman N, Ramos M, Shah M, Wallace JS, Pollitt KJG. Comparison of Airway Responses Induced in a Mouse Model by the Gas and Particulate Fractions of Gasoline Direct Injection Engine Exhaust. International Journal Of Environmental Research And Public Health 2018, 15: 429. PMID: 29494515, PMCID: PMC5876974, DOI: 10.3390/ijerph15030429.Peer-Reviewed Original ResearchConceptsAirway hyperresponsivenessAllergic asthma murine modelAsthma murine modelNon-allergic miceMethacholine responsivenessAirway responsesPulmonary responsePeripheral tissuesMurine modelMouse modelShort-term exposureAcute exposureGDI engine exhaustPolycyclic aromatic hydrocarbon metabolismUpregulation of genesHyperresponsivenessParticulate fractionHealth impactsAromatic hydrocarbon metabolismPrevalenceMiceExposureDiesel exhaustAnimalsResponse