2009
Exercise and quality of life during and after treatment for breast cancer: results of two randomized controlled trials
Cadmus LA, Salovey P, Yu H, Chung G, Kasl S, Irwin ML. Exercise and quality of life during and after treatment for breast cancer: results of two randomized controlled trials. Psycho-Oncology 2009, 18: 343-352. PMID: 19242918, PMCID: PMC4221990, DOI: 10.1002/pon.1525.Peer-Reviewed Original ResearchConceptsPost-treatment survivorsBreast cancer survivorsQuality of lifeCancer survivorsPost-treatment breast cancer survivorsHospital-based tumor registryHome-based exercise programTrial of exerciseUsual care groupEffects of exerciseSocial functioningLower social functioningAdjuvant therapyUsual careExercise interventionTumor RegistryExercise programCare groupLife impairmentBreast cancerDepressive symptomsSurvivor subgroupsHigher baselineReduced qualityLife benefitsRandomized Controlled Trial of Aerobic Exercise on Insulin and Insulin-like Growth Factors in Breast Cancer Survivors: The Yale Exercise and Survivorship Study
Irwin ML, Varma K, Alvarez-Reeves M, Cadmus L, Wiley A, Chung GG, DiPietro L, Mayne ST, Yu H. Randomized Controlled Trial of Aerobic Exercise on Insulin and Insulin-like Growth Factors in Breast Cancer Survivors: The Yale Exercise and Survivorship Study. Cancer Epidemiology Biomarkers & Prevention 2009, 18: 306-313. PMID: 19124513, PMCID: PMC2841479, DOI: 10.1158/1055-9965.epi-08-0531.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsPostmenopausal breast cancer survivorsModerate-intensity aerobic exerciseUsual care groupBreast cancer riskAerobic exerciseIGFBP-3Cancer survivorsUsual careCare groupCancer riskYale-New Haven Hospital Tumor RegistryCurrent physical activity levelsInsulin-like growth factorHospital tumor registryUsual care participantsAerobic exercise interventionExercise-induced decreasePhysical activity levelsInsulin-like growthExercise groupExercise interventionControlled TrialsTumor RegistryBrisk walking
2007
Energy balance, insulin resistance biomarkers, and breast cancer risk
Fair A, Dai Q, Shu X, Matthews C, Yu H, Jin F, Gao Y, Zheng W. Energy balance, insulin resistance biomarkers, and breast cancer risk. Cancer Epidemiology 2007, 31: 214-219. PMID: 17646056, PMCID: PMC1994998, DOI: 10.1016/j.cdp.2007.04.003.Peer-Reviewed Original ResearchMeSH KeywordsAdultAsian PeopleBiomarkersBody Mass IndexBreast NeoplasmsC-PeptideCase-Control StudiesChinaEnergy IntakeEnergy MetabolismExerciseFemaleHumansInsulin ResistanceInsulin-Like Growth Factor Binding Protein 3Insulin-Like Growth Factor IInsulin-Like Growth Factor IIMiddle AgedMotor ActivityRisk AssessmentRisk FactorsWaist-Hip RatioConceptsInsulin-like growth factorBreast cancer riskExercise/sports activitiesShanghai Breast Cancer StudyBody mass indexInsulin resistance biomarkersC-peptideCancer riskIGFBP-3Breast cancerLevels of IGFEnergy intakeInsulin growth factor binding protein 3Growth factor binding protein 3Chinese womenResistance biomarkersInsulin-like growth factor-1C-peptide levelsBreast cancer preventionPhysical activity statusSports activitiesTotal energy intakeBody fat distributionCase-control studyBreast cancer cases
2000
Role of the Insulin-Like Growth Factor Family in Cancer Development and Progression
Yu H, Rohan T. Role of the Insulin-Like Growth Factor Family in Cancer Development and Progression. Journal Of The National Cancer Institute 2000, 92: 1472-1489. PMID: 10995803, DOI: 10.1093/jnci/92.18.1472.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAlcohol DrinkingAnimalsApoptosisCase-Control StudiesCell DivisionDisease ProgressionEnergy IntakeEpidemiologic StudiesExerciseFeeding BehaviorHumansInsulin-Like Growth Factor Binding ProteinsLife StyleNeoplasmsPredictive Value of TestsPrognosisReceptors, SomatomedinSex FactorsSmokingSomatomedinsConceptsInsulin-like growth factorIGF-binding proteinsRole of IGFsEffects of IGFActions of IGFsCancer growthInsulin-like growth factor (IGF) familyGrowth factorIGF-I levelsCell proliferationIGF-I receptorHigher energy intakeGrowth factor familyIGFBP proteasesIGFBP-3Etiology of cancerMitogenic growth factorsCommon cancerCancer preventionEpidemiologic studiesHigh-energy dietCancer riskEnergy restrictionEnergy intakeCancer development